日期 影响因子
日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:
–

Randomised, sham-controlled, double-blinded, multicentre international trial to evaluate the efficacy of the Ventfree Respiratory Muscle Stimulator to assist ventilator weaning in critically ill patients: a study protocol of a randomised controlled trial

一项随机、假手术对照、双盲、多中心国际试验，旨在评估Ventfree呼吸肌刺激器辅助危重患者脱离呼吸机的疗效：一项随机对照试验的研究方案

期刊:BMJ Open
影响因子:2.3
doi:10.1136/bmjopen-2025-113540
McCaughey, Euan J; McLachlan, Angus J; Cai, Jason; Cohen Freue, Guillermo; Demoule, Alexandre; Gotur, Deepa B; Hill, Nicholas S; Dimatteo, Christopher; Oliva, Senen Pena; Patel, Mayur B; Girard, Timothy D; Heunks, Leo
发表日期：2026
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A Potent, Selective, Small-Molecule Inhibitor of DHX9 Abrogates Proliferation of Microsatellite Instable Cancers with Deficient Mismatch Repair

DHX9 的强效、选择性小分子抑制剂可抑制错配修复缺陷的微卫星不稳定癌症的增殖

期刊:Cancer Research
影响因子:12.5
doi:10.1158/0008-5472.CAN-24-0397
Jennifer Castro, Matthew H Daniels, David Brennan, Brian Johnston, Deepali Gotur, Young-Tae Lee, Kevin E Knockenhauer, Chuang Lu, Jie Wu, Sunaina Nayak, Cindy Collins, Rishabh Bansal, Shane M Buker, April Case, Julie Liu, Shihua Yao, Brian A Sparling, E Allen Sickmier, Serena J Silver, Stephen J Bla
肿瘤
发表日期：2025
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MTA-Cooperative PRMT5 Inhibitors: Mechanism Switching Through Structure-Based Design

MTA协同PRMT5抑制剂：基于结构的机制转换设计

期刊:Journal of Medicinal Chemistry
影响因子:6.8
doi:10.1021/acs.jmedchem.4c01998
Kevin M Cottrell，Douglas A Whittington，Kimberly J Briggs，Haris Jahic，Janid A Ali，Alvaro J Amor，Deepali Gotur，Matthew R Tonini，Wenhai Zhang，Alan Huang，John P Maxwell
发表日期：2025
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Discovery of ATX968: An Orally Available Allosteric Inhibitor of DHX9

ATX968 的发现：一种口服有效的 DHX9 变构抑制剂

期刊:Journal of Medicinal Chemistry
影响因子:6.8
doi:10.1021/acs.jmedchem.5c00252
Daniels, Matthew H; Castro, Jennifer; Lee, Young-Tae; Gotur, Deepali; Knockenhauer, Kevin E; Grigoriu, Simina; Lockbaum, Gordon J; Cheong, Jae Eun; Lu, Chuang; Brennan, David; Buker, Shane M; Liu, Julie; Yao, Shihua; Sparling, Brian A; Sickmier, E Allen; Ribich, Scott; Blakemore, Steve J; Silver, Serena J; Boriack-Sjodin, P Ann; Duncan, Kenneth W; Copeland, Robert A
DHX9
发表日期：2025
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Discovery of Kinesin KIF18A Inhibitor ATX020: Tactical Application of Silicon Atom Replacement

发现驱动蛋白KIF18A抑制剂ATX020：硅原子取代的战术应用

期刊:ACS Medicinal Chemistry Letters
影响因子:4
doi:10.1021/acsmedchemlett.5c00512
Sparling, Brian A; Lee, Hyelee; Zablocki, Mary-Margaret; Lynes, Maureen M; Grigoriu, Simina; Shehaj, Livia; Lockbaum, Gordon J; Khan, Sanjoy K; Hotz, Taylor; Lee, Young-Tae; Buker, Shane M; Gotur, Deepali; Lu, Chuang; Ribich, Scott; Blakemore, Stephen J; Boriack-Sjodin, P Ann; Silver, Serena J; Copeland, Robert A; Duncan, Kenneth W
发表日期：2025
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Clinical impact of idiopathic pulmonary fibrosis on SARS-CoV-2 patient outcomes: a comprehensive analysis in the pre-vaccination era

特发性肺纤维化对SARS-CoV-2患者预后的临床影响：疫苗接种前时代的一项综合分析

期刊:Frontiers in Medicine
影响因子:3
doi:10.3389/fmed.2025.1567232
Tamimi, Omar; Safdar, Zeenat; Siddiqui, Nadia; Nisar, Tariq; Gotur, Deepa
SARS-CoV-2
特发性肺纤维化
发表日期：2025
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Sialadenoma Papilliferum: An Uncommon Verruco-Papillary Lesion of the Oral Cavity

唾液腺乳头状瘤：一种罕见的口腔疣状乳头状病变

期刊:
影响因子:
doi:10.1007/s12070-024-05236-z
Gotur, Suhasini Palakshappa; Wadhwan, Vijay; Kamarthi, Nagaraju
发表日期：2025
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Discovery of TNG908: A Selective, Brain Penetrant, MTA-Cooperative PRMT5 Inhibitor That Is Synthetically Lethal with MTAP-Deleted Cancers

TNG908 的发现：一种选择性强、可穿透血脑屏障、与 MTA 协同作用的 PRMT5 抑制剂，对 MTAP 缺失的癌症具有合成致死作用

期刊:Journal of Medicinal Chemistry
影响因子:6.8
doi:10.1021/acs.jmedchem.4c00133
Kevin M Cottrell，Kimberly J Briggs，Douglas A Whittington，Haris Jahic，Janid A Ali，Charles B Davis，Shanzhong Gong，Deepali Gotur，Lina Gu，Patrick McCarren，Matthew R Tonini，Alice Tsai，Erik W Wilker，Hongling Yuan，Minjie Zhang，Wenhai Zhang，Alan Huang，John P Maxwell
血脑屏障
肿瘤
MTAP
发表日期：2024
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Cytotoxic lesion of corpus callosum secondary to phenytoin toxicity

苯妥英毒性引起的胼胝体细胞毒性损伤

期刊:Journal of Neurosciences in Rural Practice
影响因子:0.9
doi:10.25259/JNRP_468_2023
Sahib, Akhil; Gotur, Amrita
细胞生物学
毒理研究
发表日期：2024
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Ubiquitinated PCNA Drives USP1 Synthetic Lethality in Cancer

泛素化的 PCNA 驱动 USP1 在癌症中的合成致死率

期刊:Molecular Cancer Therapeutics
影响因子:5.3
doi:10.1158/1535-7163.MCT-22-0409
Antoine Simoneau #, Justin L Engel #, Madhavi Bandi #, Katherine Lazarides, Shangtao Liu, Samuel R Meier, Ashley H Choi, Hongxiang Zhang, Binzhang Shen, Lauren Martires, Deepali Gotur, Truc V Pham, Fang Li, Lina Gu, Shanzhong Gong, Minjie Zhang, Erik Wilker, Xuewen Pan, Douglas A Whittington, Scott
肿瘤
发表日期：2023
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