日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Aβ antibodies target not only amyloid plaques but also distinct brain cells and vessels.

Aβ抗体不仅靶向淀粉样斑块,还靶向特定的脑细胞和血管。

Wen Gehua, Lindblom Nils, Zhan Xiaoni, Garcia-Ryde Megg, Deierborg Tomas, Kobro-Flatmoen Asgeir, Gouras Gunnar K

Soluble cerebral Aβ protofibrils link Aβ plaque pathology to changes in CSF Aβ(42)/Aβ(40) ratios, neurofilament light and tau in Alzheimer's disease model mice

可溶性脑Aβ原纤维将Aβ斑块病理与阿尔茨海默病模型小鼠脑脊液中Aβ(42)/Aβ(40)比值、神经丝轻链和tau蛋白的变化联系起来

Andersson, Emelie; Lindblom, Nils; Janelidze, Shorena; Salvadó, Gemma; Gkanatsiou, Eleni; Söderberg, Linda; Möller, Christer; Lannfelt, Lars; Ge, Junyue; Hanrieder, Jörg; Blennow, Kaj; Deierborg, Tomas; Mattsson-Carlgren, Niklas; Zetterberg, Henrik; Gouras, Gunnar; Hansson, Oskar

Perivascular macrophages in the central nervous system: insights into their roles in health and disease

中枢神经系统血管周围巨噬细胞:对其在健康和疾病中作用的深入了解

Zhan, Xiaoni; Wang, Shuying; Bèchet, Nicholas; Gouras, Gunnar; Wen, Gehua

Neuronal endolysosomal alterations induced by Apolipoprotein E4 emerge over time in primary neurons.

载脂蛋白 E4 诱导的神经元内溶酶体改变会在原代神经元中逐渐出现

Nyberg Emma, Konings Sabine C, Lindblom Nils, Israelsson Bodil, Klementieva Oxana, Martinsson Isak, Gouras Gunnar K

One of the binding proteins for administered amyloid-β appears to be anti-Aβ IgG antibody in amyloid plaques

其中一种与外源性β-淀粉样蛋白结合的蛋白似乎是淀粉样斑块中的抗Aβ IgG抗体。

Takahashi, Reisuke H; Yokotsuka, Mayumi; Nakamura, Ayako; Nagao, Toshitaka; Gouras, Gunnar K; Uchihara, Toshiki

Lipoprotein metabolism mediates hematopoietic stem cell responses under acute anemic conditions

脂蛋白代谢介导急性贫血条件下的造血干细胞反应

Kiyoka Saito #, Mark van der Garde #, Terumasa Umemoto, Natsumi Miharada, Julia Sjöberg, Valgardur Sigurdsson, Haruki Shirozu, Shunsuke Kamei, Visnja Radulovic, Mitsuyoshi Suzuki, Satoshi Nakano, Stefan Lang, Jenny Hansson, Martin L Olsson, Takashi Minami, Gunnar Gouras, Johan Flygare, Kenichi Mihar

Microglia degrade Alzheimer's amyloid-beta deposits extracellularly via digestive exophagy

小胶质细胞通过消化外吞噬作用将阿尔茨海默病淀粉样β蛋白沉积物降解到细胞外

Rudy G Jacquet, Fernando González Ibáñez, Katherine Picard, Lucy Funes, Mohammadparsa Khakpour, Gunnar K Gouras, Marie-Ève Tremblay, Frederick R Maxfield, Santiago Solé-Domènech

Correction: Lesion of the subiculum reduces the spread of amyloid beta pathology to interconnected brain regions in a mouse model of Alzheimer's disease

更正:在阿尔茨海默病小鼠模型中,下托损伤可减少β-淀粉样蛋白病理向相互连接的脑区的扩散。

George, Sonia; Rönnbäck, Annica; Gouras, Gunnar K; Petit, Géraldine H; Grueninger, Fiona; Winblad, Bengt; Graff, Caroline; Brundin, Patrik

Correction: Apolipoprotein E intersects with amyloid-β within neurons

更正:载脂蛋白E与神经元内的β-淀粉样蛋白相互作用

Konings, Sabine C; Nyberg, Emma; Martinsson, Isak; Torres-Garcia, Laura; Klementieva, Oxana; Guimas Almeida, Claudia; Gouras, Gunnar K

Cerebral Aβ deposition precedes reduced cerebrospinal fluid and serum Aβ42/Aβ40 ratios in the AppNL-F/NL-F knock-in mouse model of Alzheimer's disease

在阿尔茨海默病的 AppNL-F/NL-F 敲入小鼠模型中,脑内 Aβ 沉积先于脑脊液和血清 Aβ42/Aβ40 比率降低

Emelie Andersson, Nina Schultz, Takashi Saito, Takaomi C Saido, Kaj Blennow, Gunnar K Gouras, Henrik Zetterberg, Oskar Hansson3