日期 影响因子
日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:
–

Prevalence of Homologous Recombination Repair Mutations and Association with Clinical Outcomes in Patients with Solid Tumors: A Study Using the AACR Project GENIE Dataset

同源重组修复突变的患病率及其与实体瘤患者临床结局的关联：一项基于AACR GENIE项目数据集的研究

期刊:Cancers
影响因子:4.4
doi:10.3390/cancers17040577
Shao, Changxia; Zhou, Heng; Chen, Cai; Dettman, Elisha J; Ren, Yixin; Cristescu, Razvan; Gozman, Alexander; Jin, Fan
发表日期：2025
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Prevalence of homologous recombination biomarkers in multiple tumor types: an observational study

同源重组生物标志物在多种肿瘤类型中的流行情况：一项观察性研究

期刊:Future Oncology
影响因子:2.6
doi:10.1080/14796694.2024.2367957
Chen, Cai; Dettman, Elisha J; Zhou, Wei; Gozman, Alexander; Jin, Fan; Lee, Liam C; Ren, Yixin; Zhou, Heng; Cristescu, Razvan; Shao, Changxia
肿瘤免疫
肿瘤
发表日期：2024
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RediScore: Prospective validation of a pipeline for homologous recombination deficiency analysis

RediScore：同源重组缺陷分析流程的前瞻性验证

期刊:Oncology Letters
影响因子:2.5
doi:10.3892/ol.2023.14060
Aikaterini Tsantikidi, Konstantinos Papazisis, Theofanis Floros, Maria Gazouli, Eirini Papadopoulou, Georgios Tsaousis, Georgios Nasioulas, Andra Mester, Kubelac Paul Milan, Bogdan Gozman, Vlad Afrasanie, Dana Lucia Stanculeanu, Oana Trifanescu, Florentina Pescaru, Claudia Militaru, Christos Papadim
信号转导
发表日期：2023
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A Role of Variance in Interferon Genes to Disease Severity in COVID-19 Patients

干扰素基因变异在新冠肺炎患者疾病严重程度中的作用

期刊:Frontiers in Genetics
影响因子:2.8
doi:10.3389/fgene.2021.709388
Gozman, Leonid; Perry, Kellie; Nikogosov, Dimitri; Klabukov, Ilya; Shevlyakov, Artem; Baranova, Ancha
肺炎
新冠
微生物学
发表日期：2021
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A Hyperactive Signalosome in Acute Myeloid Leukemia Drives Addiction to a Tumor-Specific Hsp90 Species

急性髓系白血病中过度活跃的信号体导致对肿瘤特异性 Hsp90 物种的成瘾

期刊:Cell Reports
影响因子:7.5
doi:10.1016/j.celrep.2015.10.073
Hongliang Zong, Alexander Gozman, Eloisi Caldas-Lopes, Tony Taldone, Eric Sturgill, Sarah Brennan, Stefan O Ochiana, Erica M Gomes-DaGama, Siddhartha Sen, Anna Rodina, John Koren 3rd, Michael W Becker, Charles M Rudin, Ari Melnick, Ross L Levine, Gail J Roboz, Stephen D Nimer, Gabriela Chiosis, Moni
信号转导
肿瘤
白血病
发表日期：2015
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Heat shock protein 70 inhibitors. 2. 2,5'-thiodipyrimidines, 5-(phenylthio)pyrimidines, 2-(pyridin-3-ylthio)pyrimidines, and 3-(phenylthio)pyridines as reversible binders to an allosteric site on heat shock protein 70

热休克蛋白 70 抑制剂。2. 2,5'-硫代二嘧啶、5-(苯硫基)嘧啶、2-(吡啶-3-基硫基)嘧啶和 3-(苯硫基)吡啶作为热休克蛋白 70 变构位点的可逆结合剂

期刊:Journal of Medicinal Chemistry
影响因子:6.8
doi:10.1021/jm401552y
Tony Taldone, Yanlong Kang, Hardik J Patel, Maulik R Patel, Pallav D Patel, Anna Rodina, Yogita Patel, Alexander Gozman, Ronnie Maharaj, Cristina C Clement, Alvin Lu, Jason C Young, Gabriela Chiosis
发表日期：2014
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Heat shock protein 70 inhibitors. 1. 2,5'-thiodipyrimidine and 5-(phenylthio)pyrimidine acrylamides as irreversible binders to an allosteric site on heat shock protein 70

热休克蛋白 70 抑制剂。1. 2,5'-硫代二嘧啶和 5-（苯硫基）嘧啶丙烯酰胺作为热休克蛋白 70 变构位点的不可逆结合剂

期刊:Journal of Medicinal Chemistry
影响因子:6.8
doi:10.1021/jm401551n
Yanlong Kang, Tony Taldone, Hardik J Patel, Pallav D Patel, Anna Rodina, Alexander Gozman, Ronnie Maharaj, Cristina C Clement, Maulik R Patel, Jeffrey L Brodsky, Jason C Young, Gabriela Chiosis
发表日期：2014
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Affinity purification probes of potential use to investigate the endogenous Hsp70 interactome in cancer

亲和纯化探针可用于研究癌症中的内源性 Hsp70 相互作用组

期刊:ACS Chemical Biology
影响因子:3.5
doi:10.1021/cb500256u
Anna Rodina, Tony Taldone, Yanlong Kang, Pallav D Patel, John Koren 3rd, Pengrong Yan, Erica M DaGama Gomes, Chenghua Yang, Maulik R Patel, Liza Shrestha, Stefan O Ochiana, Cristina Santarossa, Ronnie Maharaj, Alexander Gozman, Marc B Cox, Hediye Erdjument-Bromage, Ronald C Hendrickson, Leandro Cerc
肿瘤
发表日期：2014
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Identification of an allosteric pocket on human hsp70 reveals a mode of inhibition of this therapeutically important protein

人 HSP70 蛋白上变构口袋的鉴定揭示了一种抑制这种具有重要治疗价值的蛋白质的机制。

期刊:
影响因子:
doi:10.1016/j.chembiol.2013.10.008
Rodina, Anna; Patel, Pallav D; Kang, Yanlong; Patel, Yogita; Baaklini, Imad; Wong, Michael J H; Taldone, Tony; Yan, Pengrong; Yang, Chenghua; Maharaj, Ronnie; Gozman, Alexander; Patel, Maulik R; Patel, Hardik J; Chirico, William; Erdjument-Bromage, Hediye; Talele, Tanaji T; Young, Jason C; Chiosis, Gabriela
SP7
HSP70
发表日期：2013
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HSP90 is a therapeutic target in JAK2-dependent myeloproliferative neoplasms in mice and humans

HSP90 是小鼠和人类 JAK2 依赖性骨髓增生性肿瘤的治疗靶点

期刊:Journal of Clinical Investigation
影响因子:13.3
doi:10.1172/JCI42442
Sachie Marubayashi, Priya Koppikar, Tony Taldone, Omar Abdel-Wahab, Nathan West, Neha Bhagwat, Eloisi Caldas-Lopes, Kenneth N Ross, Mithat Gönen, Alex Gozman, James H Ahn, Anna Rodina, Ouathek Ouerfelli, Guangbin Yang, Cyrus Hedvat, James E Bradner, Gabriela Chiosis, Ross L Levine
肿瘤
JAK/STAT
发表日期：2010
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