日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Neoantigenic properties of TP53 variants influence cancer risk in individuals with Li-Fraumeni syndrome

TP53 变异体的新抗原特性影响李-弗劳梅尼综合征患者的癌症风险。

Montellier, Emilie; Manches, Olivier; Gaucher, Jonathan; Freycon, Claire; Hoyos, David; Blanchet, Sandrine; Verboom, Murielle; Dutzmann, Christina M; Coutant, Sophie; Bou, Jacqueline; Fin, Bertrand; Olaso, Robert; Deleuze, Jean-François; Frébourg, Thierry; Greenbaum, Benjamin D; Levine, Arnold J; Kratz, Christian P; Bougeard, Gaëlle; Hainaut, Pierre

POLQ-driven repair scars shape the immunogenic landscape of homologous recombination-deficient pancreatic cancer

POLQ驱动的修复瘢痕塑造了同源重组缺陷型胰腺癌的免疫原性图谱

Park, Wungki; Umeda, Shigeaki; Hilmi, Marc; O'Connor, Catherine; Sharma, Roshan; Tezcan, Nuray; Zhang, Haochen; Zhu, Yingjie; Schwartz, Carly; Yaqubie, Amin; Varghese, Anna; Soares, Kevin; Florou, Vaia; Kim, Daewon; Maron, Steven; Martinez, Guillem A; Balogun, Fiyinfolu; McIntyre, Caitlin; Kim, Daehee; Yu, Kenneth H; Chou, Joanne F; Hayashi, Akimasa; Keane, Fergus; Khalil, Danny; Chatila, Walid K; Capanu, Marinela; Chaligne, Ronan; Pishvaian, Michael J; Bandlamudi, Chaitanya; Lecomte, Nicolas; Berger, Michael; Basturk, Olca; Balachandran, Vinod; Pe'er, Dana; Rousseau, Benoit; Greenbaum, Benjamin; Sfeir, Agnel; Iacobuzio-Donahue, Christine; Riaz, Nadeem; O'Reilly, Eileen M

Mutant p53 Directs PARP to Regulate Replication Stress and Drive Breast Cancer Metastasis.

突变型 p53 指导 PARP 调节复制压力并驱动乳腺癌转移。

Xiao Gu, Annor George K, Harmon Katherine W, Chavez Valery, Levine Fayola, Ahuno Samuel, Atmane Mohamed I, St Jean Samantha, Madorsky Rowdo Florencia P, Leybengrub Pamella, Gaglio AnnMarie, Ellison Viola, Venkatesh Divya, Sun Siyu, Merghoub Taha, Greenbaum Benjamin, Elemento Olivier, Davis Melissa B, Ogunwobi Olorunseun, Bargonetti Jill

An inflammatory biomarker signature of response to CAR-T cell therapy in non-Hodgkin lymphoma

非霍奇金淋巴瘤对 CAR-T 细胞疗法反应的炎症生物标志物特征

Raj, Sandeep S; Fei, Teng; Fried, Shalev; Ip, Andrew; Fein, Joshua A; Leslie, Lori A; Alarcon Tomas, Ana; Leithner, Doris; Peled, Jonathan U; Corona, Magdalena; Dahi, Parastoo B; Danylesko, Ivetta; Epstein-Peterson, Zachary; Funnell, Tyler; Giralt, Sergio A; Jacoby, Elad; Kedmi, Meirav; Landego, Ivan; Lin, Richard J; Parascondola, Allison; Pascual, Lauren; Orozco, Natali; Park, Jae H; Palomba, M Lia; Salles, Gilles; Saldia, Amethyst; Schöder, Heiko; Sdayoor, Inbal; Shah, Gunjan L; Scordo, Michael; Shem-Tov, Noga; Shimoni, Avichai; Slingerland, John; Yerushalmi, Ronit; Nagler, Arnon; Greenbaum, Benjamin D; Vickers, Andrew J; Suh, Hyung C; Avigdor, Abraham; Perales, Miguel-Angel; van den Brink, Marcel R M; Shouval, Roni

RNA neoantigen vaccines prime long-lived CD8(+) T cells in pancreatic cancer

RNA新抗原疫苗可激活胰腺癌中的长寿命CD8(+) T细胞

Sethna, Zachary; Guasp, Pablo; Reiche, Charlotte; Milighetti, Martina; Ceglia, Nicholas; Patterson, Erin; Lihm, Jayon; Payne, George; Lyudovyk, Olga; Rojas, Luis A; Pang, Nan; Ohmoto, Akihiro; Amisaki, Masataka; Zebboudj, Abderezak; Odgerel, Zagaa; Bruno, Emmanuel M; Zhang, Siqi Linsey; Cheng, Charlotte; Elhanati, Yuval; Derhovanessian, Evelyna; Manning, Luisa; Müller, Felicitas; Rhee, Ina; Yadav, Mahesh; Merghoub, Taha; Wolchok, Jedd D; Basturk, Olca; Gönen, Mithat; Epstein, Andrew S; Momtaz, Parisa; Park, Wungki; Sugarman, Ryan; Varghese, Anna M; Won, Elizabeth; Desai, Avni; Wei, Alice C; D'Angelica, Michael I; Kingham, T Peter; Soares, Kevin C; Jarnagin, William R; Drebin, Jeffrey; O'Reilly, Eileen M; Mellman, Ira; Sahin, Ugur; Türeci, Özlem; Greenbaum, Benjamin D; Balachandran, Vinod P

IL-33-activated ILC2s induce tertiary lymphoid structures in pancreatic cancer.

IL-33激活的ILC2诱导胰腺癌中的三级淋巴结构

Amisaki Masataka, Zebboudj Abderezak, Yano Hiroshi, Zhang Siqi Linsey, Payne George, Chandra Adrienne Kaya, Yu Rebecca, Guasp Pablo, Sethna Zachary M, Ohmoto Akihiro, Rojas Luis A, Cheng Charlotte, Waters Theresa, Solovyov Alexander, Martis Stephen, Doane Ashley S, Reiche Charlotte, Bruno Emmanuel M, Milighetti Martina, Soares Kevin, Odgerel Zagaa, Moral John Alec, Zhao Julia N, Gönen Mithat, Gardner Rui, Tumanov Alexei V, Khan Abdul G, Vergnolle Olivia, Nyakatura Elisabeth K, Lorenz Ivo C, Baca Manuel, Patterson Erin, Greenbaum Benjamin, Artis David, Merghoub Taha, Balachandran Vinod P

Chronic Viral Mimicry Induction following p53 Loss Promotes Immune Evasion.

p53 缺失后诱导慢性病毒模拟可促进免疫逃逸。

Ishak Charles A, Marhon Sajid A, Tchrakian Naïri, Hodgson Anjelica, Loo Yau Helen, Gonzaga Isabela M, Peralta Melanie, Lungu Ilinca M, Gomez Stephanie, Liang Sheng-Ben, Shen Shu Yi, Chen Raymond, Chen Jocelyn, Chatterjee Biji, Wanniarachchi Kevin N, Lee Junwoo, Zehrbach Nicholas, Hosseini Amir, Mehdipour Parinaz, Sun Siyu, Solovyov Alexander, Ettayebi Ilias, Francis Kyle E, He Aobo, Wu Taiyi, Feng Shengrui, da Silva Medina Tiago, Campos de Almeida Felipe, Bayani Jane, Li Jason, MacDonald Spencer, Wang Yadong, Garcia Sarah S, Arthofer Elisa, Diab Noor, Srivastava Aneil, Austin Paul Tran, Sabatini Peter J B, Greenbaum Benjamin D, O'Brien Catherine A, Shepherd Trevor G, Tsao Ming Sound, Chiappinelli Katherine B, Oza Amit M, Clarke Blaise A, Rottapel Robert, Lheureux Stephanie, De Carvalho Daniel D

Restoration of the Tumor Suppressor Function of Y220C-Mutant p53 by Rezatapopt, a Small-Molecule Reactivator.

Rezatapopt(一种小分子激活剂)可恢复 Y220C 突变 p53 的肿瘤抑制功能

Puzio-Kuter Anna M, Xu Lizhong, McBrayer Mary Kate, Dominique Romyr, Li Hongju H, Fahr Bruce J, Brown Alyssa M, Wiebesiek Amy E, Russo Brandon M, Mulligan Chris L, Yang Hong, Battaglia Josh, Robell Kimberly A, Thomas Dafydd H, Huang Kuo-Sen, Solovyov Alexander, Greenbaum Benjamin D, Oliner Jonathan D, Davis Thomas W, Dumble Melissa L, Johnson Melissa L, Xiong Shunbin, Yang Peirong, Lozano Guillermina, Fellous Marc M, Vu Binh T, Schram Alison M, Levine Arnold J, Poyurovsky Masha V

Pan-cancer multi-omic model of LINE-1 activity reveals locus heterogeneity of retrotransposition efficiency

LINE-1活性泛癌多组学模型揭示逆转录转座效率的位点异质性

Solovyov, Alexander; Behr, Julie M; Hoyos, David; Banks, Eric; Drong, Alexander W; Thornlow, Bryan; Zhong, Jimmy Z; Garcia-Rivera, Enrique; McKerrow, Wilson; Chu, Chong; Arisdakessian, Cedric; Zaller, Dennis M; Kamihara, Junne; Diao, Liyang; Fromer, Menachem; Greenbaum, Benjamin D

Deciphering the Code of Viral-Host Adaptation Through Maximum-Entropy Nucleotide Bias Models

利用最大熵核苷酸偏倚模型破译病毒-宿主适应密码

Di Gioacchino, Andrea; Lecce, Ivan; Greenbaum, Benjamin D; Monasson, Rémi; Cocco, Simona