Retraction Note: Polymerase θ inhibition activates the cGAS-STING pathway and cooperates with immune checkpoint blockade in models of BRCA-deficient cancer
撤稿声明:聚合酶θ抑制剂可激活cGAS-STING通路,并在BRCA缺陷型癌症模型中与免疫检查点阻断剂协同作用。
期刊:Nature Communications
影响因子:15.7
doi:10.1038/s41467-023-43803-0
Patterson-Fortin, Jeffrey; Jadhav, Heta; Pantelidou, Constantia; Phan, Tin; Grochala, Carter; Mehta, Anita K; Guerriero, Jennifer L; Wulf, Gerburg M; Wolpin, Brian M; Stanger, Ben Z; Aguirre, Andrew J; Cleary, James M; D'Andrea, Alan D; Shapiro, Geoffrey I
肿瘤
肿瘤免疫
信号转导
cGAS-STING
STING
免疫/内分泌