Guido Sebastiani相关文献与解析，生知库 | 链接生命科学的每一步

日期影响因子

Comprehensive sequencing profile and functional analysis of IsomiRs in human pancreatic islets and beta cells

人胰岛和β细胞中异构体寡核苷酸（IsomiR）的全面测序谱和功能分析

期刊:Diabetologia

影响因子:8.4

doi:10.1007/s00125-025-06397-4

Stefano Auddino ,Elena Aiello ,Giuseppina E Grieco ,Daniela Fignani ,Giada Licata ,Marco Bruttini ,Alessia Mori ,Andrea F Berteramo ,Erika Pedace ,Laura Nigi ,Caterina Formichi ,Claudiane Guay ,Giuseppe Quero ,Vincenzo Tondolo ,Gianfranco Di Giuseppe ,Laura Soldovieri ,Gea Ciccarelli ,Andrea Mari ,Andrea Giaccari ,Teresa Mezza ,Agnese Po ,Romano Regazzi ,Francesco Dotta ,Guido Sebastiani

细胞生物学

发表日期：2025

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Pancreatic beta-cell IL-22 receptor deficiency induces age-dependent dysregulation of insulin biosynthesis and systemic glucose homeostasis

胰岛β细胞IL-22受体缺乏会导致与年龄相关的胰岛素生物合成和全身葡萄糖稳态失调。

期刊:Nature Communications

影响因子:14.7

doi:10.1038/s41467-024-48320-2

Haressh Sajiir ,Kuan Yau Wong ,Alexandra Müller ,Sahar Keshvari ,Lucy Burr ,Elena Aiello ,Teresa Mezza ,Andrea Giaccari ,Guido Sebastiani ,Francesco Dotta ,Grant A Ramm ,Graeme A Macdonald ,Michael A McGuckin ,Johannes B Prins ,Sumaira Z Hasnain

免疫/内分泌

细胞生物学

发表日期：2024

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A set of circulating microRNAs belonging to the 14q32 chromosome locus identifies two subgroups of individuals with recent-onset type 1 diabetes

一组位于14q32染色体位点的循环microRNA可识别出两组近期发病的1型糖尿病患者。

期刊:Cell Reports Medicine

影响因子:11.7

doi:10.1016/j.xcrm.2024.101591

Guido Sebastiani ，Giuseppina Emanuela Grieco ，Marco Bruttini ，Stefano Auddino ，Alessia Mori ，Mattia Toniolli ，Daniela Fignani ，Giada Licata ，Elena Aiello ，Laura Nigi ，Caterina Formichi ，Juan Fernandez-Tajes ，Alberto Pugliese ，Carmella Evans-Molina ，Lut Overbergh ，Timothy Tree ，Mark Peakman ，Chantal Mathieu ，Francesco Dotta

发表日期：2024

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Intra-islet insulin synthesis defects are associated with endoplasmic reticulum stress and loss of beta cell identity in human diabetes

胰岛内胰岛素合成缺陷与人类糖尿病中的内质网应激和β细胞特性丧失有关

期刊:Diabetologia

影响因子:8.4

doi:10.1007/s00125-022-05814-2.

Noemi Brusco ,Guido Sebastiani ,Gianfranco Di Giuseppe ,Giada Licata ,Giuseppina E Grieco ,Daniela Fignani ,Laura Nigi ,Caterina Formichi ,Elena Aiello ,Stefano Auddino ,Giuseppe Quero ,Chiara M A Cefalo ,Francesca Cinti ,Andrea Mari ,Pietro M Ferraro ,Alfredo Pontecorvi ,Sergio Alfieri ,Andrea Giaccari ,Francesco Dotta ,Teresa Mezza

发表日期：2023

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Angiotensin I-converting enzyme type 2 expression is increased in pancreatic islets of type 2 diabetic donors

2 型糖尿病患者胰岛中血管紧张素转换酶 2 型表达增加

期刊:Diabetes-Metabolism Research and Reviews

影响因子:4.6

doi:10.1002/dmrr.3696

Daniela Fignani, Erika Pedace, Giada Licata, Giuseppina Emanuela Grieco, Elena Aiello, Carmela de Luca, Lorella Marselli, Piero Marchetti, Guido Sebastiani, Francesco Dotta

发表日期：2023

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NF-κB-inducing kinase (NIK) is activated in pancreatic β-cells but does not contribute to the development of diabetes

NF-κB诱导激酶（NIK）在胰岛β细胞中被激活，但并不参与糖尿病的发生发展。

期刊:Cell Death & Disease

影响因子:8.1

doi:10.1038/s41419-022-04931-5

Peng Xiao # ，Tatiana Takiishi # ，Natalia Moretti Violato ，Giada Licata ，Francesco Dotta ，Guido Sebastiani ，Lorella Marselli ，Sumeet Pal Singh ，Mozes Sze ，Geert Van Loo ，Emmanuel Dejardin ，Esteban Nicolas Gurzov ，Alessandra Kupper Cardozo

细胞生物学

发表日期：2022

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Reduced miR-184-3p expression protects pancreatic β-cells from lipotoxic and proinflammatory apoptosis in type 2 diabetes via CRTC1 upregulation

miR-184-3p 表达降低可通过 CRTC1 上调保护胰腺 β 细胞免于 2 型糖尿病中的脂毒性和促炎性细胞凋亡

期刊:Cell Death Discovery

影响因子:6.1

doi:10.1038/s41420-022-01142-x

Giuseppina E Grieco #, Noemi Brusco #, Daniela Fignani, Laura Nigi, Caterina Formichi, Giada Licata, Lorella Marselli, Piero Marchetti, Laura Salvini, Laura Tinti, Agnese Po, Elisabetta Ferretti, Guido Sebastiani, Francesco Dotta

细胞生物学

发表日期：2022

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Increased Expression of Viral Sensor MDA5 in Pancreatic Islets and in Hormone-Negative Endocrine Cells in Recent Onset Type 1 Diabetic Donors

近期发病的 1 型糖尿病患者胰岛和激素阴性内分泌细胞中病毒传感器 MDA5 表达增加

期刊:Frontiers in Immunology

影响因子:5.7

doi:10.3389/fimmu.2022.833141

Laura Nigi, Noemi Brusco, Giuseppina E Grieco, Daniela Fignani, Giada Licata, Caterina Formichi, Elena Aiello, Lorella Marselli, Piero Marchetti, Lars Krogvold, Knut Dahl Jorgensen, Guido Sebastiani, Francesco Dotta

发表日期：2022

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Identification and Validation of miR-222-3p and miR-409-3p as Plasma Biomarkers in Gestational Diabetes Mellitus Sharing Validated Target Genes Involved in Metabolic Homeostasis

鉴定并验证 miR-222-3p 和 miR-409-3p 作为妊娠期糖尿病血浆生物标志物，共享涉及代谢稳态的已验证靶基因

期刊:International Journal of Molecular Sciences

影响因子:0.7

doi:10.3390/ijms23084276

Tiziana Filardi, Giuseppina Catanzaro, Giuseppina Emanuela Grieco, Elena Splendiani, Sofia Trocchianesi, Carmela Santangelo, Roberto Brunelli, Elisa Guarino, Guido Sebastiani, Francesco Dotta, Susanna Morano, Elisabetta Ferretti

发表日期：2022

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Protocol to analyze circulating small non-coding RNAs by high-throughput RNA sequencing from human plasma samples

通过高通量 RNA 测序分析人类血浆样本中的循环小非编码 RNA 的方案

期刊:STAR Protocols

影响因子:1.3

doi:10.1016/j.xpro.2021.100606

Giuseppina E Grieco, Guido Sebastiani, Daniela Fignani, Noemi Brusco, Laura Nigi, Caterina Formichi, Giada Licata, Marco Bruttini, Romina D'Aurizio, Chantal Mathieu, Conny Gysemans, Francesco Dotta

发表日期：2021

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