Viral expression of NE/PPE enhances anti-colorectal cancer efficacy of oncolytic adenovirus by promoting TAM M1 polarization to reverse insufficient effector memory/effector CD8(+) T cell infiltration.
NE/PPE 的病毒表达通过促进 TAM M1 极化来逆转效应记忆/效应 CD8(+) T 细胞浸润不足，从而增强溶瘤腺病毒的抗结直肠癌疗效
期刊:Journal of Experimental & Clinical Cancer Research
影响因子:12.8
doi:10.1186/s13046-025-03358-y
Wang Shuo, Kong Lingkai, Wang Linpei, Zhuang Yan, Guo Ciliang, Zhang Yuxin, Cui Huawei, Gu Xiaosong, Wu Junhua, Jiang Chunping
