Bispecific antibodies and CAR T cells targeting a TP53 mutation-associated neoantigen show discordant affinity requirements.
针对TP53突变相关新抗原的双特异性抗体和CAR T细胞表现出不一致的亲和力要求。
期刊:Journal of Clinical Investigation
影响因子:13.6
doi:10.1172/JCI192885
DiNapoli Sarah R, Wright Katharine M, Mog Brian J, Pearlman Alexander H, Nichakawade Tushar D, Marcou Nikita, Hsiue Emily Han-Chung, Hwang Michael S, Douglass Jacqueline, Liu Qiang, Watson Evangeline, Dal Molin Marco, Cohen Joshua D, Popoli Maria, Paul Suman, Konig Maximilian F, Wyhs Nicolas, Azurmendi P Aitana, Glavaris Stephanie, Ge Jiaxin, Awosika Tolulope O, Liu Jin, Gabrielson Kathleen L, Gabelli Sandra B, Pardoll Drew M, Bettegowda Chetan, Papadopoulos Nickolas, Kinzler Kenneth W, Zhou Shibin, Vogelstein Bert
