文献库，生知库 | 链接生命科学的每一步

日期影响因子

Exploration of chemical space with partial labeled noisy student self-training and self-supervised graph embedding

利用部分标记噪声学生自训练和自监督图嵌入探索化学空间

期刊:BMC Bioinformatics

影响因子:3.3

doi:10.1186/s12859-022-04681-3

Liu, Yang; Lim, Hansaim; Xie, Lei

发表日期：2022

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HMI-PRED 2.0: a biologist-oriented web application for prediction of host-microbe protein-protein interaction by interface mimicry

HMI-PRED 2.0：一款面向生物学家的网络应用程序，用于通过界面模拟预测宿主-微生物蛋白质-蛋白质相互作用

doi:10.1093/bioinformatics/btac633

Lim, Hansaim; Tsai, Chung-Jung; Keskin, Ozlem; Nussinov, Ruth; Gursoy, Attila

发表日期：2022

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MSA-Regularized Protein Sequence Transformer toward Predicting Genome-Wide Chemical-Protein Interactions: Application to GPCRome Deorphanization

基于MSA正则化的蛋白质序列转换器预测全基因组化学-蛋白质相互作用：应用于GPCR组去孤儿化

期刊:Journal of Chemical Information and Modeling

影响因子:5.3

doi:10.1021/acs.jcim.0c01285

Cai, Tian; Lim, Hansaim; Abbu, Kyra Alyssa; Qiu, Yue; Nussinov, Ruth; Xie, Lei

GPCR/Calcium/cAMP

多发性硬化症

发表日期：2021

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A Bayesian approach to accurate and robust signature detection on LINCS L1000 data

基于贝叶斯方法的LINCS L1000数据精确稳健的特征检测

doi:10.1093/bioinformatics/btaa064

Qiu, Yue; Lu, Tianhuan; Lim, Hansaim; Xie, Lei

发表日期：2020

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Rational discovery of dual-indication multi-target PDE/Kinase inhibitor for precision anti-cancer therapy using structural systems pharmacology

利用结构系统药理学合理发现用于精准抗癌治疗的双适应症多靶点PDE/激酶抑制剂

期刊:PLoS Computational Biology

影响因子:3.6

doi:10.1371/journal.pcbi.1006619

Lim, Hansaim; He, Di; Qiu, Yue; Krawczuk, Patrycja; Sun, Xiaoru; Xie, Lei

发表日期：2019

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Biological representation of chemicals using latent target interaction profile

利用潜在靶标相互作用谱对化学物质进行生物学表征

期刊:BMC Bioinformatics

影响因子:3.3

doi:10.1186/s12859-019-3241-3

Ayed, Mohamed; Lim, Hansaim; Xie, Lei

发表日期：2019

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Target Gene Prediction of Transcription Factor Using a New Neighborhood-regularized Tri-factorization One-class Collaborative Filtering Algorithm

基于新型邻域正则化三因子分解单类协同过滤算法的转录因子靶基因预测

doi:10.1145/3233547.3233551

Lim, Hansaim; Xie, Lei

发表日期：2018

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ANTENNA, a Multi-Rank, Multi-Layered Recommender System for Inferring Reliable Drug-Gene-Disease Associations: Repurposing Diazoxide as a Targeted Anti-Cancer Therapy

ANTENNA，一种用于推断可靠药物-基因-疾病关联的多级、多层推荐系统：将二氮嗪重新用于靶向抗癌疗法

期刊:Ieee-Acm Transactions on Computational Biology and Bioinformatics

doi:10.1109/TCBB.2018.2812189

Annie Wang, Hansaim Lim, Shu-Yuan Cheng, Lei Xie

发表日期：2018

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