日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Palbociclib and dsRNA sensor co-operate to enhance anti-cancer effects through ER stress and modulation of immune evasion

Palbociclib 和 dsRNA 传感器协同作用,通过内质网应激和调节免疫逃逸来增强抗癌作用。

Victoria Roulstone # ,Joan Kyula-Currie # ,James Wright ,Emmanuel C Patin ,Isaac Dean ,Lu Yu ,Aida Barreiro-Alonso ,Miriam Melake ,Jyoti Choudhary ,Richard Elliott ,Christopher J Lord ,David Mansfield ,Nik Matthews ,Ritika Chauhan ,Victoria Jennings ,Charleen Chan Wah Hak ,Holly Baldock ,Francesca Butera ,Elizabeth Appleton ,Pablo Nenclares ,Malin Pedersen ,Shane Foo ,Amarin Wongariyapak ,Antonio Rullan ,Tencho Tenev ,Pascal Meier ,Richard Vile ,Hardev Pandha ,Alan Melcher ,Martin McLaughlin ,Kevin J Harrington

Solving selectivity issues in LBAs: case study using Gyrolab to quantify CB307, a bispecific Humabody in human serum

解决 LBA 中的选择性问题:使用 Gyrolab 量化人血清中的双特异性抗体 CB307 的案例研究

Thomas Wilford, Phillip D Bartlett, Anna Schlag, Lukas Jasaitis, Hardev Pandha, Andrew J Pierce, Richard Hughes

The dysfunctional immune response in renal cell carcinoma correlates with changes in the metabolic landscape of ccRCC during disease progression

肾细胞癌中的免疫反应功能障碍与疾病进展过程中 ccRCC 代谢景观的变化相关

Nicola E Annels, M Denyer, D Nicol, S Hazell, A Silvanto, M Crockett, M Hussain, Carla Moller-Levet, Hardev Pandha

Oncolytic virus-mediated expansion of dual-specific CAR T cells improves efficacy against solid tumors in mice

溶瘤病毒介导的双特异性CAR-T细胞扩增可提高小鼠实体瘤的治疗效果。

Laura Evgin ,Tim Kottke ,Jason Tonne ,Jill Thompson ,Amanda L Huff ,Jacob van Vloten ,Madelyn Moore ,Josefine Michael ,Christopher Driscoll ,Jose Pulido ,Eric Swanson ,Richard Kennedy ,Matt Coffey ,Houra Loghmani ,Luis Sanchez-Perez ,Gloria Olivier ,Kevin Harrington ,Hardev Pandha ,Alan Melcher ,Rosa Maria Diaz ,Richard G Vile

CD4 T cell dynamics shape the immune response to combination oncolytic herpes virus and BRAF inhibitor therapy for melanoma

CD4 T 细胞动力学影响溶瘤疱疹病毒和 BRAF 抑制剂联合治疗黑色素瘤的免疫反应

Galabina Bozhanova, Jehanne Hassan, Lizzie Appleton, Victoria Jennings, Shane Foo, Martin McLaughlin, Charleen Ml Chan Wah Hak, Emmanuel C Patin, Eva Crespo-Rodriguez, Gabby Baker, Edward Armstrong, Matthew Chiu, Hardev Pandha, Adel Samson, Victoria Roulstone, Joan Kyula, Richard Vile, Fiona Erringt

Oncolytic virotherapy induced CSDE1 neo-antigenesis restricts VSV replication but can be targeted by immunotherapy

溶瘤病毒疗法诱导的CSDE1新抗原生成会限制VSV复制,但可通过免疫疗法进行靶向治疗。

Timothy Kottke ,Jason Tonne ,Laura Evgin ,Christopher B Driscoll ,Jacob van Vloten ,Victoria A Jennings ,Amanda L Huff ,Brady Zell ,Jill M Thompson ,Phonphimon Wongthida ,Jose Pulido ,Matthew R Schuelke ,Adel Samson ,Peter Selby ,Elizabeth Ilett ,Mark McNiven ,Lewis R Roberts ,Mitesh J Borad ,Hardev Pandha ,Kevin Harrington ,Alan Melcher ,Richard G Vile

Antiviral antibody responses to systemic administration of an oncolytic RNA virus: the impact of standard concomitant anticancer chemotherapies

抗病毒抗体对全身施用溶瘤 RNA 病毒的反应:标准伴随抗癌化疗的影响

Victoria Roulstone, David Mansfield, Robert J Harris, Katie Twigger, Christine White, Johann de Bono, James Spicer, Sophia N Karagiannis, Richard Vile, Hardev Pandha, Alan Melcher, Kevin Harrington

The evolutionarily conserved long non-coding RNA LINC00261 drives neuroendocrine prostate cancer proliferation and metastasis via distinct nuclear and cytoplasmic mechanisms

进化保守的长链非编码 RNA LINC00261 通过独特的核和细胞质机制驱动神经内分泌前列腺癌增殖和转移

Rebecca L Mather, Abhijit Parolia, Sandra E Carson, Erik Venalainen, David Roig-Carles, Mustapha Jaber, Shih-Chun Chu, Ilaria Alborelli, Rebecca Wu, Dong Lin, Noushin Nabavi, Elena Jachetti, Mario P Colombo, Hui Xue, Perla Pucci, Xinpei Ci, Cheryl Hawkes, Yinglei Li, Hardev Pandha, Igor Ulitsky, Cry

Integration of Urinary EN2 Protein & Cell-Free RNA Data in the Development of a Multivariable Risk Model for the Detection of Prostate Cancer Prior to Biopsy

整合尿液 EN2 蛋白和游离 RNA 数据,开发活检前检测前列腺癌的多变量风险模型

Shea P Connell, Robert Mills, Hardev Pandha, Richard Morgan, Colin S Cooper, Jeremy Clark, Daniel S Brewer, The Movember Gap Urine Biomarker Consortium

APOBEC3B-mediated corruption of the tumor cell immunopeptidome induces heteroclitic neoepitopes for cancer immunotherapy

APOBEC3B 介导的肿瘤细胞免疫肽组破坏会诱导异质新表位用于癌症免疫治疗

Christopher B Driscoll #, Matthew R Schuelke #, Timothy Kottke, Jill M Thompson, Phonphimon Wongthida, Jason M Tonne, Amanda L Huff, Amber Miller, Kevin G Shim, Amy Molan, Cynthia Wetmore, Peter Selby, Adel Samson, Kevin Harrington, Hardev Pandha, Alan Melcher, Jose S Pulido, Reuben Harris, Laura Ev