Heiner Schäfer相关文献与解析，生知库 | 链接生命科学的每一步

Claudia Geismann #, Charlotte Hauser #, Frauke Grohmann, Christian Schneeweis, Nico Bölter, Jan-Paul Gundlach, Günter Schneider, Christoph Röcken, Christian Meinhardt, Heiner Schäfer, Stefan Schreiber, Alexander Arlt

代谢

信号转导

细胞生物学

Hepatic myofibroblasts exert immunosuppressive effects independent of the immune checkpoint regulator PD-L1 in liver metastasis of pancreatic ductal adenocarcinoma

肝肌成纤维细胞在胰腺导管腺癌肝转移中发挥不依赖于免疫检查点调节因子PD-L1的免疫抑制作用

期刊:Frontiers in Oncology

影响因子:3.5

doi:10.3389/fonc.2023.1160824

Silje Beckinger ，Tina Daunke ，Leon Aldag ，Sandra Krüger ，Steffen Heckl ，Daniela Wesch ，Heiner Schäfer ，Christoph Röcken ，Sascha Rahn ，Susanne Sebens

Monocarboxylate Transporter-1 (MCT1)-Mediated Lactate Uptake Protects Pancreatic Adenocarcinoma Cells from Oxidative Stress during Glutamine Scarcity Thereby Promoting Resistance against Inhibitors of Glutamine Metabolism

单羧酸转运蛋白-1 (MCT1) 介导的乳酸摄取可在谷氨酰胺缺乏期间保护胰腺腺癌细胞免受氧化应激，从而促进对谷氨酰胺代谢抑制剂的抵抗力

期刊:Antioxidants

影响因子:

doi:10.3390/antiox12101818

Nourhane Ammar, Maya Hildebrandt, Claudia Geismann, Christian Röder, Timo Gemoll, Susanne Sebens, Ania Trauzold, Heiner Schäfer

TRAIL-receptor 2-a novel negative regulator of p53

TRAIL受体2-一种新的p53负调节剂

期刊:Cell Death & Disease

影响因子:8.1

doi:10.1038/s41419-021-04048-1

Anna Willms, Hella Schupp, Michelle Poelker, Alshaimaa Adawy, Jan Frederik Debus, Torsten Hartwig, Tim Krichel, Jürgen Fritsch, Steven Singh, Henning Walczak, Silvia von Karstedt, Heiner Schäfer, Anna Trauzold

TRAIL-receptor 2-a novel negative regulator of p53

TRAIL受体2——p53的一种新型负调控因子

期刊:

影响因子:8.1

doi:PMC8325694

Anna Willms，Hella Schupp，Michelle Poelker，Alshaimaa Adawy，Jan Frederik Debus，Torsten Hartwig，Tim Krichel，Jürgen Fritsch，Steven Singh，Henning Walczak ，Silvia von Karstedt ，Heiner Schäfer，Anna Trauzold

Programmed Death-Ligand 1 (PD-L1) Expression Is Induced by Insulin in Pancreatic Ductal Adenocarcinoma Cells Pointing to Its Role in Immune Checkpoint Control

胰岛素诱导胰腺导管腺癌细胞中的程序性死亡配体 1 (PD-L1) 表达，表明其在免疫检查点控制中发挥作用

期刊:Medical Sciences

影响因子:

doi:10.3390/medsci9030048

Steffen M Heckl, Franziska Mau, Anke Senftleben, Tina Daunke, Silje Beckinger, Samir Abdullazade, Stefan Schreiber, Christoph Röcken, Susanne Sebens, Heiner Schäfer

Impact of the Monocarboxylate Transporter-1 (MCT1)-Mediated Cellular Import of Lactate on Stemness Properties of Human Pancreatic Adenocarcinoma Cells †

单羧酸转运蛋白-1（MCT1）介导的乳酸细胞输入对人类胰腺腺癌细胞干性特性的影响†

期刊:Cancers

影响因子:

doi:10.3390/cancers12030581

Leontine Sandforth, Nourhane Ammar, Lisa Antonia Dinges, Christoph Röcken, Alexander Arlt, Susanne Sebens, Heiner Schäfer

Inflammation Associated Pancreatic Tumorigenesis: Upregulation of Succinate Dehydrogenase (Subunit B) Reduces Cell Growth of Pancreatic Ductal Epithelial Cells

炎症相关的胰腺肿瘤发生：琥珀酸脱氢酶（亚基 B）的上调会降低胰腺导管上皮细胞的细胞生长

期刊:Cancers

影响因子:

doi:10.3390/cancers12010042

Sascha Rahn, Philippe Dänzer Barbosa, Julia Luisa Möller, Nourhane Ammar, Tobias Demetrowitsch, Ole Helm, Daniela Wesch, Bence Sipos, Christoph Röcken, Karin Schwarz, Heiner Schäfer, Susanne Sebens

Diabetes as risk factor for pancreatic cancer: Hyperglycemia promotes epithelial-mesenchymal-transition and stem cell properties in pancreatic ductal epithelial cells

糖尿病是胰腺癌的危险因素：高血糖促进胰腺导管上皮细胞的上皮-间质转化和干细胞特性

期刊:Cancer Letters

影响因子:9.1

doi:10.1016/j.canlet.2017.12.004

Sascha Rahn, Vivien Zimmermann, Fabrice Viol, Hendrike Knaack, Kerstin Stemmer, Lena Peters, Lennart Lenk, Hendrik Ungefroren, Dieter Saur, Heiner Schäfer, Ole Helm, Susanne Sebens

TRAIL/NF-κB/CX3CL1 Mediated Onco-Immuno Crosstalk Leading to TRAIL Resistance of Pancreatic Cancer Cell Lines

TRAIL/NF-κB/CX3CL1介导的肿瘤免疫串扰导致胰腺癌细胞系对TRAIL产生耐药性

期刊:International Journal of Molecular Sciences

影响因子:0.7

doi:10.3390/ijms19061661

Claudia Geismann, Wiebke Erhart, Frauke Grohmann, Stefan Schreiber, Günter Schneider, Heiner Schäfer, Alexander Arlt

NF-κB/RelA controlled A20 limits TRAIL-induced apoptosis in pancreatic cancer

NF-κB/RelA 控制的 A20 限制 TRAIL 诱导的胰腺癌细胞凋亡

Hepatic myofibroblasts exert immunosuppressive effects independent of the immune checkpoint regulator PD-L1 in liver metastasis of pancreatic ductal adenocarcinoma

肝肌成纤维细胞在胰腺导管腺癌肝转移中发挥不依赖于免疫检查点调节因子PD-L1的免疫抑制作用

Monocarboxylate Transporter-1 (MCT1)-Mediated Lactate Uptake Protects Pancreatic Adenocarcinoma Cells from Oxidative Stress during Glutamine Scarcity Thereby Promoting Resistance against Inhibitors of Glutamine Metabolism

单羧酸转运蛋白-1 (MCT1) 介导的乳酸摄取可在谷氨酰胺缺乏期间保护胰腺腺癌细胞免受氧化应激，从而促进对谷氨酰胺代谢抑制剂的抵抗力

TRAIL-receptor 2-a novel negative regulator of p53

TRAIL受体2-一种新的p53负调节剂

TRAIL-receptor 2-a novel negative regulator of p53

TRAIL受体2——p53的一种新型负调控因子

Programmed Death-Ligand 1 (PD-L1) Expression Is Induced by Insulin in Pancreatic Ductal Adenocarcinoma Cells Pointing to Its Role in Immune Checkpoint Control

胰岛素诱导胰腺导管腺癌细胞中的程序性死亡配体 1 (PD-L1) 表达，表明其在免疫检查点控制中发挥作用

Impact of the Monocarboxylate Transporter-1 (MCT1)-Mediated Cellular Import of Lactate on Stemness Properties of Human Pancreatic Adenocarcinoma Cells †

单羧酸转运蛋白-1（MCT1）介导的乳酸细胞输入对人类胰腺腺癌细胞干性特性的影响†

Inflammation Associated Pancreatic Tumorigenesis: Upregulation of Succinate Dehydrogenase (Subunit B) Reduces Cell Growth of Pancreatic Ductal Epithelial Cells

炎症相关的胰腺肿瘤发生：琥珀酸脱氢酶（亚基 B）的上调会降低胰腺导管上皮细胞的细胞生长

Diabetes as risk factor for pancreatic cancer: Hyperglycemia promotes epithelial-mesenchymal-transition and stem cell properties in pancreatic ductal epithelial cells

糖尿病是胰腺癌的危险因素：高血糖促进胰腺导管上皮细胞的上皮-间质转化和干细胞特性

TRAIL/NF-κB/CX3CL1 Mediated Onco-Immuno Crosstalk Leading to TRAIL Resistance of Pancreatic Cancer Cell Lines

TRAIL/NF-κB/CX3CL1介导的肿瘤免疫串扰导致胰腺癌细胞系对TRAIL产生耐药性