日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Integrin β1, myosin light chain kinase and myosin IIA are required for activation of PI3K-AKT signaling following MEK inhibition in metastatic triple negative breast cancer.

在转移性三阴性乳腺癌中,MEK 抑制后,PI3K-AKT 信号通路的激活需要整合素 β1、肌球蛋白轻链激酶和肌球蛋白 IIA

Choi Cheolwon, Kwon Junyeob, Lim Sunyoung, Helfman David M

Germinal center-specific protein human germinal center associated lymphoma directly interacts with both myosin and actin and increases the binding of myosin to actin

生发中心特异性蛋白(人生发中心相关淋巴瘤)直接与肌球蛋白和肌动蛋白相互作用,并增强肌球蛋白与肌动蛋白的结合。

Lu, Xiaoqing; Kazmierczak, Katarzyna; Jiang, Xiaoyu; Jones, Michelle; Watt, James; Helfman, David M; Moore, Jeffrey R; Szczesna-Cordary, Danuta; Lossos, Izidore S

HGAL, a germinal center specific protein, decreases lymphoma cell motility by modulation of the RhoA signaling pathway.

HGAL 是一种生发中心特异性蛋白,它通过调节 RhoA 信号通路来降低淋巴瘤细胞的运动能力

Jiang Xiaoyu, Lu Xiaoqing, McNamara George, Liu Xiaofei, Cubedo Elena, Sarosiek Kristopher A, Sánchez-García Isidro, Helfman David M, Lossos Izidore S

HGAL, a lymphoma prognostic biomarker, interacts with the cytoskeleton and mediates the effects of IL-6 on cell migration

HGAL是一种淋巴瘤预后生物标志物,它与细胞骨架相互作用,并介导IL-6对细胞迁移的影响。

Lu, Xiaoqing; Chen, Jun; Malumbres, Raquel; Cubedo Gil, Elena; Helfman, David M; Lossos, Izidore S

A critical role of tropomyosins in TGF-beta regulation of the actin cytoskeleton and cell motility in epithelial cells

原肌球蛋白在TGF-β调控上皮细胞肌动蛋白细胞骨架和细胞运动中的关键作用

Bakin, Andrei V; Safina, Alfiya; Rinehart, Cammie; Daroqui, Cecilia; Darbary, Huferesh; Helfman, David M

Post-transcriptional down-regulation of ROCKI/Rho-kinase through an MEK-dependent pathway leads to cytoskeleton disruption in Ras-transformed fibroblasts

通过 MEK 依赖性通路对 ROCKI/Rho 激酶进行转录后下调,导致 Ras 转化成纤维细胞的细胞骨架破坏。

Pawlak, Geraldine; Helfman, David M