日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Genomic and immunogenomic profiling of extramedullary acute myeloid leukemia reveals actionable clonal branching and frequent immune editing

髓外急性髓系白血病的基因组和免疫基因组分析揭示了可操作的克隆分支和频繁的免疫编辑

Collignon, Clément; Hansen, Tucker; Hercus, Colin; Ruzinova, Marianna B; Roth Guepin, Gabrielle; Bonmati, Caroline; Rubio, Marie Thérèse; Feugier, Pierre; Gaudfrin, Mélanie; Sartelet, Hervé; Divoux, Marion; Muller, Marc; Heath, Sharon; Uy, Geoffrey L; Spencer, David H; Chen, David Y; Pagliuca, Simona; Ferraro, Francesca

βc receptor antagonism mitigates sarcoidosis granuloma formation by targeting inflammatory signals and aberrant lipid metabolism

βc受体拮抗剂通过靶向炎症信号和异常脂质代谢来减轻结节病肉芽肿的形成。

Wang, Hao; Tumes, Damon J; Keam, Simon; Lim, Jia Wen; Nguyen, Quynh Anh; Vlahos, Ross; McQualter, Jonathan; Quek, Adam; Whyte, Carly; Pant, Harshita; Hercus, Timothy R; Wilson, Nicholas J; Reynolds, Paul N; Owczarek, Catherine M; Lopez, Angel F; Bozinovski, Steven; Yip, Kwok Ho

Geometric Tuning of Cytokine Receptor Association Modulates Synthetic Agonist Signaling

细胞因子受体结合的几何调控调节合成激动剂信号传导

Expòsit, Marc; Abedi, Mohamad; Krishnakumar, Aditya; Jain, Shruti; Yu, Ta-Yi; Hercus, Timothy R; Mathew, Divij; Gray-Gaillard, Sophie; Chen, Zhijie; Grubbe, William S; Favor, Andrew; Kan, Winnie L; Schlichthaerle, Thomas; Chen, Wei; Parker, Michael W; Mendoza, Juan L; Lopez, Angel F; Wherry, E John; Baker, David

Roles of chromosomal and gonadal sex in the fetal and placental responses to maternal food restriction in mice

染色体和性腺性别在小鼠胎儿和胎盘对母体食物限制反应中的作用

Hercus, Jess C; Salcedo Rubio, Daniel Alejandro; Osorio Nieto, Maria Elisa; Keum, Cheayeong; Wang, Qi; Macdonald, John A; Scott, Jordan S; Lucas, Emily R J; Christians, Julian K

CBL mutations in chronic myelomonocytic leukemia often occur in the RING domain with multiple subclones per patient: Implications for targeting

慢性粒单核细胞白血病中的 CBL 突变通常发生在 RING 结构域中,每个患者有多个亚克隆:对靶向治疗的意义

Kelly Lim, Winnie L Kan, Pramod C Nair, Monika Kutyna, Angel F Lopez, Timothy Hercus, David M Ross, Steven Lane, Chun Yew Fong, Anna Brown, Agnes Yong, David Yeung, Timothy Hughes, Devendra Hiwase, Daniel Thomas

Distinct Assemblies of Heterodimeric Cytokine Receptors Govern Stemness Programs in Leukemia

异二聚体细胞因子受体的不同组装体调控白血病干细胞程序

Winnie L Kan # ,Urmi Dhagat # ,Kerstin B Kaufmann # ,Timothy R Hercus # ,Tracy L Nero # ,Andy G X Zeng # ,John Toubia # ,Emma F Barry ,Sophie E Broughton ,Guillermo A Gomez ,Brooks A Benard ,Mara Dottore ,Karen S Cheung Tung Shing ,Héléna Boutzen ,Saumya E Samaraweera ,Kaylene J Simpson ,Liqing Jin ,Gregory J Goodall ,C Glenn Begley ,Daniel Thomas ,Paul G Ekert ,Denis Tvorogov ,Richard J D'Andrea ,John E Dick ,Michael W Parker ,Angel F Lopez

Leukemia relapse via genetic immune escape after allogeneic hematopoietic cell transplantation

异基因造血干细胞移植后通过基因免疫逃逸导致白血病复发

Pagliuca, Simona; Gurnari, Carmelo; Hercus, Colin; Hergalant, Sébastien; Hong, Sanghee; Dhuyser, Adele; D'Aveni, Maud; Aarnink, Alice; Rubio, Marie Thérèse; Feugier, Pierre; Ferraro, Francesca; Carraway, Hetty E; Sobecks, Ronald; Hamilton, Betty K; Majhail, Navneet S; Visconte, Valeria; Maciejewski, Jaroslaw P

Molecular landscape of immune pressure and escape in aplastic anemia

再生障碍性贫血中免疫压力和逃逸的分子图谱

Pagliuca, Simona; Gurnari, Carmelo; Hercus, Colin; Hergalant, Sébastien; Nadarajah, Niroshan; Wahida, Adam; Terkawi, Laila; Mori, Minako; Zhou, Weiyin; Visconte, Valeria; Spellman, Stephen; Gadalla, Shahinaz M; Zhu, Caiying; Zhu, Ping; Haferlach, Torsten; Maciejewski, Jaroslaw P

Leukemia relapse via genetic immune escape after allogeneic hematopoietic cell transplantation

异基因造血干细胞移植后通过基因免疫逃逸导致白血病复发

Pagliuca, Simona; Gurnari, Carmelo; Hercus, Colin; Hergalant, Sébastien; Hong, Sanghee; Dhuyser, Adele; D'Aveni, Maud; Aarnink, Alice; Rubio, Marie Thérèse; Feugier, Pierre; Ferraro, Francesca; Carraway, Hetty E; Sobecks, Ronald; Hamilton, Betty K; Majhail, Navneet S; Visconte, Valeria; Maciejewski, Jaroslaw P

Blocking the human common beta subunit of the GM-CSF, IL-5 and IL-3 receptors markedly reduces hyperinflammation in ARDS models

阻断人类 GM-CSF、IL-5 和 IL-3 受体的共同 β 亚基可显著降低 ARDS 模型中的过度炎症

Hao Wang, Damon J Tumes, Timothy R Hercus, K H Yip, Christian Aloe, Ross Vlahos, Angel F Lopez, Nick Wilson, Catherine M Owczarek, Steven Bozinovski