日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Limited effects of the REV-ERB agonist SR9009 after mouse spinal cord contusion: Reduced acute pathology with unaffected functional recovery and chronic white matter loss

REV-ERB激动剂SR9009对小鼠脊髓挫伤的影响有限:减轻急性病理损伤,功能恢复不受影响,但慢性白质丢失也未受影响。

Slomnicki, Lukasz P; Hodges, Emily; Armstrong, Christine; Morehouse, Johnny; Burke, Darlene; Ohri, Sujata Saraswat; Burris, Thomas P; Hetman, Michal

Mutation-specific impairment of TET2 and DNMT3A enzymatic activity predicts clonal hematopoiesis disease risk

TET2 和 DNMT3A 酶活性的突变特异性损害可预测克隆性造血疾病风险。

Pershad, Yash; Zhao, Kun; Van Amburg, Joseph C; Corty, Robert W; Parker, Alyssa C; Silver, Alexander J; Almadani, Yara; Kishtagari, Ashwin; Hodges, Emily; Savona, Michael R; Heimlich, J Brett; Bick, Alexander G

Pancreatic islet β-cell subtypes are derived from biochemically-distinct and nutritionally-regulated islet progenitors

胰岛β细胞亚型来源于生化特性不同且受营养调控的胰岛祖细胞。

Brown, Monica E; Miranda, Verda E; Nevills, Simone; Hu, Ruiying; Dadi, Prasanna K; Simmons, Alan J; Xu, Yanwen; Yang, Yilin; Yagan, Mahircan; Najam, Sadia; Sampson, Leesa L; Magnuson, Mark A; Jacobson, David A; Lau, Ken S; Hodges, Emily; Gu, Guoqiang

Human TSC2 mutant cells exhibit aberrations in early neurodevelopment accompanied by changes in the DNA Methylome.

人类 TSC2 突变细胞在早期神经发育中表现出异常,并伴有 DNA 甲基化组的变化

Chalkley Mary-Bronwen L, Guerin Lindsey N, Iyer Tenhir, Mallahan Samantha, Nelson Sydney, Sahin Mustafa, Hodges Emily, Ess Kevin C, Ihrie Rebecca A

Genomic dissection and mutation-specific target discovery for breast cancer PIK3CA hotspot mutations

乳腺癌PIK3CA热点突变的基因组解析和突变特异性靶点发现

Miranda, Adam X; Kemp, Justin; Davidson, Brad A; Bellomo, Sara Erika; Miranda, Verda E; Manoni, Alexandra; Marchiò, Caterina; Croessmann, Sarah; Park, Ben H; Hodges, Emily

Cross-tissue patterns of DNA hypomethylation reveal genetically distinct histories of cell development

不同组织中DNA低甲基化的模式揭示了细胞发育的遗传差异历史

Scott, Timothy J; Hansen, Tyler J; McArthur, Evonne; Hodges, Emily

Human gene regulatory evolution is driven by the divergence of regulatory element function in both cis and trans

人类基因调控进化是由顺式和反式调控元件功能的分化驱动的。

Hansen, Tyler; Fong, Sarah; Capra, John A; Hodges, Emily

Role of circadian rhythms in pathogenesis of acute CNS injuries: Insights from experimental studies

昼夜节律在急性中枢神经系统损伤发病机制中的作用:来自实验研究的启示

Hetman, Michal; Slomnicki, Lukasz P; Hodges, Emily R; Saraswat Ohri, Sujata; Whittemore, Scott R

ATAC-Me Captures Prolonged DNA Methylation of Dynamic Chromatin Accessibility Loci during Cell Fate Transitions.

ATAC-Me 可捕获细胞命运转变过程中动态染色质可及位点的持续 DNA 甲基化

Barnett Kelly R, Decato Benjamin E, Scott Timothy J, Hansen Tyler J, Chen Bob, Attalla Jonathan, Smith Andrew D, Hodges Emily

Neanderthal introgression reintroduced functional ancestral alleles lost in Eurasian populations

尼安德特人的基因渗入重新引入了欧亚人群中丢失的功能性祖先等位基因。

Rinker, David C; Simonti, Corinne N; McArthur, Evonne; Shaw, Douglas; Hodges, Emily; Capra, John A