日期 影响因子
日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:
–

To generate functional anti-protease-activated receptor-4 (PAR4), a G protein-coupled receptor, antibodies through PAR4-mRNA-LNP immunization

为了生成功能性抗蛋白酶激活受体4 (PAR4)（一种G蛋白偶联受体）抗体，可通过PAR4-mRNA-LNP免疫接种实现。

期刊:NPJ Vaccines
影响因子:6.5
doi:10.1038/s41541-025-01283-x
Liu, En-Shuo; Ho, Kai-Wen; Wu, Chin-Chung; Fan, Hsiao-Li; Wang, Ting-Yu; Hsieh, Yuan-Chin; Huang, Bo-Cheng; Hong, Shih-Ting; Liao, Tzu-Yi; Liu, Yen-Ling; Chen, Yu-Tung; Lee, Chia-Ching; Chen, Chiao-Yun; Lin, Chih-Lung; Cheng, Tian-Lu
PAR4
信号转导
免疫/内分泌
发表日期：2025
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Spatial-hindrance-based pro-Adalimumab prevents anti-idiotypic antibody interference in pharmacokinetic and therapeutic efficacy.

基于空间阻碍的pro-Adalimumab可防止抗独特型抗体干扰药代动力学和治疗效果

期刊:Bioengineering & Translational Medicine
影响因子:5.7
doi:10.1002/btm2.70015
Huang Bo-Cheng, Chen Yu-Tung, Lu Yun-Chi, Ho Kai-Wen, Hong Shih-Ting, Liao Tzu-Yi, Wu I-Hsuan, Liu En-Shuo, Liao Jun-Min, Chen Fang-Ming, Li Chia-Ching, Chuang Chih-Hung, Chen Chiao-Yun, Cheng Tian-Lu
免疫/内分泌
发表日期：2025
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A universal in silico V(D)J recombination strategy for developing humanized monoclonal antibodies.

一种用于开发人源化单克隆抗体的通用计算机模拟V(D)J重组策略

期刊:Journal of Nanobiotechnology
影响因子:12.6
doi:10.1186/s12951-022-01259-2
Hsieh Yuan-Chin, Liao Jun-Min, Chuang Kuo-Hsiang, Ho Kai-Wen, Hong Shih-Ting, Liu Hui-Ju, Huang Bo-Cheng, Chen I-Ju, Liu Yen-Ling, Wang Jaw-Yuan, Tsai Hsiang-Lin, Su Yu-Cheng, Wang Yen-Tseng, Cheng Tian-Lu
其它
Human
发表日期：2022
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Selective activation of pro-anti-IL-1β antibody enhances specificity for autoinflammatory disorder therapy.

选择性激活促抗IL-1β抗体可增强自身炎症性疾病治疗的特异性

期刊:Scientific Reports
影响因子:3.9
doi:10.1038/s41598-021-94298-y
Lin Wen-Wei, Lu Yun-Chi, Huang Bo-Cheng, Chuang Chih-Hung, Cheng Yi-An, Chen I-Ju, Liu Hui-Ju, Ho Kai-Wen, Liao Tzu-Yi, Liu En-Shuo, Wu Ting-Yi, Chang Long-Sen, Hong Shih-Ting, Cheng Tian-Lu
免疫/内分泌
炎症
发表日期：2021
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