日期 影响因子
日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:
–

To generate functional anti-protease-activated receptor-4 (PAR4), a G protein-coupled receptor, antibodies through PAR4-mRNA-LNP immunization

为了生成功能性抗蛋白酶激活受体4 (PAR4)（一种G蛋白偶联受体）抗体，可通过PAR4-mRNA-LNP免疫接种实现。

期刊:NPJ Vaccines
影响因子:6.5
doi:10.1038/s41541-025-01283-x
Liu, En-Shuo; Ho, Kai-Wen; Wu, Chin-Chung; Fan, Hsiao-Li; Wang, Ting-Yu; Hsieh, Yuan-Chin; Huang, Bo-Cheng; Hong, Shih-Ting; Liao, Tzu-Yi; Liu, Yen-Ling; Chen, Yu-Tung; Lee, Chia-Ching; Chen, Chiao-Yun; Lin, Chih-Lung; Cheng, Tian-Lu
PAR4
信号转导
免疫/内分泌
发表日期：2025
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Spatial-hindrance-based pro-Adalimumab prevents anti-idiotypic antibody interference in pharmacokinetic and therapeutic efficacy.

基于空间阻碍的pro-Adalimumab可防止抗独特型抗体干扰药代动力学和治疗效果

期刊:Bioengineering & Translational Medicine
影响因子:5.7
doi:10.1002/btm2.70015
Huang Bo-Cheng, Chen Yu-Tung, Lu Yun-Chi, Ho Kai-Wen, Hong Shih-Ting, Liao Tzu-Yi, Wu I-Hsuan, Liu En-Shuo, Liao Jun-Min, Chen Fang-Ming, Li Chia-Ching, Chuang Chih-Hung, Chen Chiao-Yun, Cheng Tian-Lu
免疫/内分泌
发表日期：2025
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Ketohexokinase-dependent metabolism of cerebral endogenous fructose in microglia drives diabetes-associated cognitive dysfunction

小胶质细胞中酮己糖激酶依赖的脑内源性果糖代谢导致糖尿病相关的认知功能障碍

期刊:Experimental and Molecular Medicine
影响因子:9.5
doi:10.1038/s12276-023-01112-y
Yansong Li #, Tao Jiang #, Mengyu Du #, Shuxuan He, Ning Huang, Bo Cheng, Chaoying Yan, Wenxin Tang, Wei Gao, Hongyan Guo, Qiao Li, Qiang Wang
代谢
糖尿病
胶质细胞
发表日期：2023
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Exploring the effects of skeletal architecture and muscle properties on bipedal standing in the common chimpanzee (Pan troglodytes) from the perspective of biomechanics

从生物力学的角度探讨骨骼结构和肌肉特性对普通黑猩猩（Pan troglodytes）双足站立的影响

期刊:Frontiers in Bioengineering and Biotechnology
影响因子:4.8
doi:10.3389/fbioe.2023.1140262
Xv, Xiao-Wei; Chen, Wen-Bin; Xiong, Cai-Hua; Huang, Bo; Cheng, Long-Fei; Sun, Bai-Yang
发表日期：2023
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A universal in silico V(D)J recombination strategy for developing humanized monoclonal antibodies.

一种用于开发人源化单克隆抗体的通用计算机模拟V(D)J重组策略

期刊:Journal of Nanobiotechnology
影响因子:12.6
doi:10.1186/s12951-022-01259-2
Hsieh Yuan-Chin, Liao Jun-Min, Chuang Kuo-Hsiang, Ho Kai-Wen, Hong Shih-Ting, Liu Hui-Ju, Huang Bo-Cheng, Chen I-Ju, Liu Yen-Ling, Wang Jaw-Yuan, Tsai Hsiang-Lin, Su Yu-Cheng, Wang Yen-Tseng, Cheng Tian-Lu
其它
Human
发表日期：2022
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Selective activation of pro-anti-IL-1β antibody enhances specificity for autoinflammatory disorder therapy.

选择性激活促抗IL-1β抗体可增强自身炎症性疾病治疗的特异性

期刊:Scientific Reports
影响因子:3.9
doi:10.1038/s41598-021-94298-y
Lin Wen-Wei, Lu Yun-Chi, Huang Bo-Cheng, Chuang Chih-Hung, Cheng Yi-An, Chen I-Ju, Liu Hui-Ju, Ho Kai-Wen, Liao Tzu-Yi, Liu En-Shuo, Wu Ting-Yi, Chang Long-Sen, Hong Shih-Ting, Cheng Tian-Lu
免疫/内分泌
炎症
发表日期：2021
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Specific activation of pro-Infliximab enhances selectivity and safety of rheumatoid arthritis therapy

特异性激活前体英夫利昔单抗可增强类风湿性关节炎治疗的选择性和安全性

期刊:PLoS Biology
影响因子:7.2
doi:10.1371/journal.pbio.3000286
Lu, Yun-Chi; Chuang, Chih-Hung; Chuang, Kuo-Hsiang; Chen, I-Ju; Huang, Bo-Cheng; Lee, Wen-Han; Wang, Hsin-Ell; Li, Jia-Je; Cheng, Yi-An; Cheng, Kai-Wen; Wang, Jaw-Yuan; Hsieh, Yuan-Chin; Lin, Wen-Wei; Cheng, Tian-Lu
关节炎
发表日期：2019
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Celecoxib suppresses cutaneous squamous-cell carcinoma cell migration via inhibition of SDF1-induced endocytosis of CXCR4

塞来昔布通过抑制 SDF1 诱导的 CXCR4 内吞作用来抑制皮肤鳞状细胞癌细胞迁移

期刊:Oncotargets and Therapy
影响因子:2.7
doi:10.2147/OTT.S180472
Ting Gong, Yan Yu, Bo Yang, Min Lin, Jin-Wen Huang, Bo Cheng, Chao Ji
肿瘤
皮肤癌
肿瘤细胞
发表日期：2018
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