日期 影响因子
日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:
–

Physiologically Based Pharmacokinetic Modeling of Biologic Case Studies in Monkeys and Humans Reveals the Necessity of an Additional Clearance Term

基于生理的药代动力学模型对猴子和人类生物案例研究揭示了增加清除期的必要性

期刊:Pharmaceutics
影响因子:5.5
doi:10.3390/pharmaceutics17050560
Stader, Felix; Sharma, Pradeep; Huang, Weize; Choules, Mary P; Willemin, Marie-Emilie; Zhang, Xinwen; Yau, Estelle; Derbalah, Abdallah; Zyla, Adriana; Liu, Cong; Sepp, Armin
Human
Monkey
发表日期：2025
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"Digital twins elucidate critical role of T(scm) in clinical persistence of TCR-engineered cell therapy"

“数字孪生阐明了T(scm)在TCR工程化细胞疗法的临床持久性中的关键作用”

期刊:npj Systems Biology and Applications
影响因子:3.5
doi:10.1038/s41540-024-00335-7
Joslyn, Louis R; Huang, Weize; Miles, Dale; Hosseini, Iraj; Ramanujan, Saroja
细胞生物学
发表日期：2024
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Incorporating Uremic Solute-mediated Inhibition of OAT1/3 Improves PBPK Prediction of Tenofovir Renal and Systemic Disposition in Patients with Severe Kidney Disease.

将尿毒症溶质介导的 OAT1/3 抑制纳入 PBPK 预测，可改善重度肾病患者替诺福韦肾脏和全身分布情况

期刊:Pharmaceutical Research
影响因子:4.3
doi:10.1007/s11095-023-03594-x
Chang Shih-Yu, Huang Weize, Chapron Alenka, Quiñones Antonio J López, Wang Joanne, Isoherranen Nina, Shen Danny D, Kelly Edward J, Himmelfarb Jonathan, Yeung Catherine K
信号转导
发表日期：2023
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CYP2D6 Activity Is Correlated with Changes in Plasma Concentrations of Taurocholic Acid during Pregnancy and Postpartum in CYP2D6 Extensive Metabolizers

在CYP2D6广泛代谢者中，CYP2D6活性与妊娠期和产后血浆牛磺胆酸浓度的变化相关

期刊:Drug Metabolism and Disposition
影响因子:4
doi:10.1124/dmd.123.001358
Czuba, Lindsay C; Malhotra, Karan; Enthoven, Luke; Fay, Emily E; Moreni, Sue L; Mao, Jennie; Shi, Yuanyuan; Huang, Weize; Totah, Rheem A; Isoherranen, Nina; Hebert, Mary F
代谢
发表日期：2023
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Clinical Pharmacology Perspectives for Adoptive Cell Therapies in Oncology

肿瘤过继细胞疗法的临床药理学展望

期刊:Clinical Pharmacology & Therapeutics
影响因子:5.5
doi:10.1002/cpt.2509
Huang, Weize; Li, Junyi; Liao, Michael Z; Liu, Stephanie N; Yu, Jiajie; Jing, Jing; Kotani, Naoki; Kamen, Lynn; Guelman, Sebastian; Miles, Dale R
细胞生物学
肿瘤
肿瘤免疫
发表日期：2022
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Development of a pediatric physiologically-based pharmacokinetic model to support recommended dosing of atezolizumab in children with solid tumors

建立基于儿科生理的药代动力学模型，以支持阿特珠单抗在实体瘤患儿中的推荐剂量。

期刊:Frontiers in Pharmacology
影响因子:4.8
doi:10.3389/fphar.2022.974423
Huang, Weize; Stader, Felix; Chan, Phyllis; Shemesh, Colby S; Chen, Yuan; Gill, Katherine L; Jones, Hannah M; Li, Linzhong; Rossato, Gianluca; Wu, Benjamin; Jin, Jin Y; Chanu, Pascal
发表日期：2022
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Population Pharmacokinetics and Exposure-Response Analyses for Venetoclax in Combination with R-CHOP in Relapsed/Refractory and Previously Untreated Patients with Diffuse Large B Cell Lymphoma

维奈托克联合R-CHOP方案治疗复发/难治性及既往未接受治疗的弥漫性大B细胞淋巴瘤患者的群体药代动力学和暴露-反应分析

期刊:Advances in Therapy
影响因子:4
doi:10.1007/s12325-021-01919-z
Samineni, Divya; Huang, Weize; Gibiansky, Leonid; Ding, Hao; Zhang, Rong; Li, Chunze; Sinha, Arijit; Rajwanshi, Richa; Humphrey, Kathryn; Bazeos, Alexandra; Salem, Ahmed Hamed; Miles, Dale
B细胞
HOP
淋巴瘤
CHOP
细胞生物学
免疫/内分泌
发表日期：2022
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Novel Mechanistic PBPK Model to Predict Renal Clearance in Varying Stages of CKD by Incorporating Tubular Adaptation and Dynamic Passive Reabsorption

通过整合肾小管适应和动态被动重吸收，构建预测CKD不同阶段肾清除率的新型机制性PBPK模型

期刊:Cpt-Pharmacometrics & Systems Pharmacology
影响因子:3
doi:10.1002/psp4.12553
Huang, Weize; Isoherranen, Nina
发表日期：2020
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Development of a Dynamic Physiologically Based Mechanistic Kidney Model to Predict Renal Clearance

开发基于动态生理机制的肾脏模型以预测肾清除率

期刊:Cpt-Pharmacometrics & Systems Pharmacology
影响因子:3
doi:10.1002/psp4.12321
Huang, Weize; Isoherranen, Nina
发表日期：2018
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Physiologically Based Pharmacokinetic Model of the CYP2D6 Probe Atomoxetine: Extrapolation to Special Populations and Drug-Drug Interactions

基于生理的CYP2D6探针阿托莫西汀药代动力学模型：向特殊人群和药物相互作用的推断

期刊:Drug Metabolism and Disposition
影响因子:4
doi:10.1124/dmd.117.076455
Huang, Weize; Nakano, Mariko; Sager, Jennifer; Ragueneau-Majlessi, Isabelle; Isoherranen, Nina
发表日期：2017
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