Targeting PLK1-CBX8-GPX4 axis overcomes BRAF/EGFR inhibitor resistance in BRAFV600E colorectal cancer via ferroptosis.
通过铁死亡靶向 PLK1-CBX8-GPX4 轴可克服 BRAFV600E 结直肠癌中的 BRAF/EGFR 抑制剂耐药性
期刊:Nature Communications
影响因子:15.7
doi:10.1038/s41467-025-58992-z
Zhao Zhan, He Jiashuai, Qiu Shenghui, Wang Lu, Huangfu Shuchen, Hu Yangzhi, Wu Qing, Yang Yabing, Li Xiaobo, Huang Maohua, Liu Shijin, Guan Hanyang, Chen Zuyang, Zhang Xiangwei, Zhang Yiran, Ding Hui, Zhao Xiaoxu, Xiao Guandi, Pan Yunlong, Liu Tongzheng, Wu Yanping, Pan Jinghua
