文献库，生知库 | 链接生命科学的每一步

Po-Hsien Chiu ,Kuan-Chen Lai ,Hung-Ling Wang ,Yao-Wen Chang ,Wen-Chi Wu ,Tien-Hua Chen ,Yu-Shuen Tsai ,Jie-Hong Song ,Nai-Yun Sun ,Gar-Yang Chau ,Wen-Liang Fang ,Ju-Pei Chen ,Hung-Ming Wang ,Huai-Cheng Huang ,Meng-Che Hsieh ,Chun-Hung Hua ,Ming-Yu Lien ,Yi-Fang Chang ,Hui-Ching Wang ,Chih-Yen Chien ,Tai-Lin Huang ,Chen-Chi Wang ,Yi-Chun Liu ,Jo-Pai Chen ,Wei-Chen Lu ,Ching-Yi Yiu ,Chien-Liang Lin ,Pei-Jen Lou ,Pen-Yuan Chu ,Shao-Chun Wang ,Mien-Chie Hung ,Muh-Hwa Yang

免疫/内分泌

肿瘤

STAT1

Taming Pancreatic Cancer: Ardisia virens Kurz-Derived 4-Hydroxy-2-Methoxy-6-Tridecylphenyl Acetate as a Potent Tubulin Polymerization Inhibitor for Targeted Pancreatic Ductal Adenocarcinoma Therapy

控制胰腺癌：紫金牛衍生的 4-羟基-2-甲氧基-6-十三烷基苯基乙酸酯作为有效的微管蛋白聚合抑制剂用于靶向胰腺导管腺癌治疗

期刊:International Journal of Medical Sciences

影响因子:3.2

doi:10.7150/ijms.104112

Chia-Hung Yen, Chien-Ju Lin, Peng-Yu Chen, Yi-Jin Chen, Ling-Rung Wei, Pei-Hsuan Chen, Yi-Chen Yeh, Lily Hui-Ching Wang, Hsun-Shuo Chang, Wan-Chi Tsai

The relationships among psychosocial impact, professional type, and vaccine hesitancy among healthcare workers during the COVID-19 pandemic

新冠疫情期间医护人员的心理社会影响、职业类型和疫苗犹豫之间的关系

期刊:BMC Psychology

影响因子:3

doi:10.1186/s40359-025-03452-y

Huang, Joh-Jong; Chou, Frank Huang-Chih; Hsu, Su-Ting; Hsieh, Kuan-Ying; Lin, Guei-Ging; Wu, Pei-Jhen; Liu, Chin-Lien; Wu, Hui-Ching; Wang, Wen-Chun; Li, Dian-Jeng

Hydrogen sulfide coordinates glucose metabolism switch through destabilizing tetrameric pyruvate kinase M2

硫化氢通过破坏四聚体丙酮酸激酶M2的稳定性来协调葡萄糖代谢转换。

期刊:Nature Communications

影响因子:14.7

doi:10.1038/s41467-024-51875-9

Rong-Hsuan Wang ,Pin-Ru Chen ,Yue-Ting Chen ,Yi-Chang Chen ,Yu-Hsin Chu ,Chia-Chen Chien ,Po-Chen Chien ,Shao-Yun Lo ,Zhong-Liang Wang ,Min-Chen Tsou ,Ssu-Yu Chen ,Guang-Shen Chiu ,Wen-Ling Chen ,Yi-Hsuan Wu ,Lily Hui-Ching Wang ,Wen-Ching Wang ,Shu-Yi Lin ,Hsing-Jien Kung ,Lu-Hai Wang ,Hui-Chun Cheng ,Kai-Ti Lin

Systematic Studies on the Anti-SARS-CoV-2 Mechanisms of Tea Polyphenol-Related Natural Products

茶多酚类天然产物抗新冠病毒机制的系统研究

期刊:ACS Omega

影响因子:3.7

doi:10.1021/acsomega.4c02392

Chen-Wei Li, Tai-Ling Chao, Chin-Lan Lai, Cheng-Chin Lin, Max Yu-Chen Pan, Chieh-Ling Cheng, Chih-Jung Kuo, Lily Hui-Ching Wang, Sui-Yuan Chang, Po-Huang Liang

Neuron-derived neurotensin promotes pancreatic cancer invasiveness and gemcitabine resistance via the NTSR1/Akt pathway

神经元衍生的神经降压素通过 NTSR1/Akt 通路促进胰腺癌侵袭性和吉西他滨耐药性

期刊:American Journal of Cancer Research

影响因子:3.6

doi:10.62347/UAKN9541

Yu-Hsuan Hung, Hui-Ching Wang, Shih-Han Hsu, Li-Yun Wang, Ya-Li Tsai, Yung-Yeh Su, Wen-Chun Hung, Li-Tzong Chen

Chromatin Remodeling-Related PRDM1 Increases Stomach Cancer Proliferation and Is Counteracted by Bromodomain Inhibitor

染色质重塑相关的 PRDM1 促进胃癌增殖，并被溴结构域抑制剂所抵消

期刊:Journal of Personalized Medicine

影响因子:3

doi:10.3390/jpm14030224

Yu-Hsuan Hung, Hui-Ching Wang, Mei-Ren Pan, Li-Tzong Chen

Biomarker potential of nuclear Nrf2 activation in the ABC subtype of diffuse large B‑cell lymphoma

弥漫大 B 细胞淋巴瘤 ABC 亚型中核 Nrf2 激活的生物标志物潜力

期刊:Oncology Letters

影响因子:2.5

doi:10.3892/ol.2024.14776

Chin-Mu Hsu, Shih-Yu Kao, Chia-Hung Yen, Chi-En Hsiao, Shih-Feng Cho, Hui-Ching Wang, Tsung-Jang Yeh, Jeng-Shiun Du, Min-Hong Wang, Tzu-Yu Hsieh, Samuel Yien Hsiao, Yuhsin Tsai, Li-Chuan Hung, Yi-Chang Liu, Kung-Chao Chang, Hui-Hua Hsiao

Precise Control of Intracellular Trafficking and Receptor-Mediated Endocytosis in Living Cells and Behaving Animals

精确控制活细胞和行为动物中的细胞内运输和受体介导的内吞作用

期刊:Advanced Science

影响因子:

doi:10.1002/advs.202405568

Shiau-Chi Chen, Neng-Jie Zeng, Grace Y Liu, Hsien-Chu Wang, Tzu-Ying Lin, Yi-Ling Tai, Chiao-Yun Chen, Yin Fang, Yi-Chien Chuang, Ching-Lin Kao, Hsuan Cheng, Bing-Huang Wu, Pin-Chiao Sun, Odvogmed Bayansan, Yu-Ting Chiu, Chi-Hsuan Shih, Wen-Hong Chung, Jia-Bin Yang, Lily Hui-Ching Wang, Po-Han Chian

The Prognosis Performance of a Neutrophil- and Lymphocyte-Associated Gene Mutation Score in a Head and Neck Cancer Cohort

中性粒细胞和淋巴细胞相关基因突变评分在头颈癌队列中的预后表现

期刊:Biomedicines

影响因子:3.9

doi:10.3390/biomedicines11123113

Tsung-Jang Yeh, Hui-Ching Wang, Shih-Feng Cho, Chun-Chieh Wu, Tzu-Yu Hsieh, Chien-Tzu Huang, Min-Hong Wang, Tzer-Ming Chuang, Yuh-Ching Gau, Jeng-Shiun Du, Yi-Chang Liu, Hui-Hua Hsiao, Mei-Ren Pan, Li-Tzong Chen, Sin-Hua Moi0

Therapeutic stress triggers tumor STAT1 acetylation to disarm immunotherapy

治疗应激触发肿瘤STAT1乙酰化，从而削弱免疫疗法

Taming Pancreatic Cancer: Ardisia virens Kurz-Derived 4-Hydroxy-2-Methoxy-6-Tridecylphenyl Acetate as a Potent Tubulin Polymerization Inhibitor for Targeted Pancreatic Ductal Adenocarcinoma Therapy

控制胰腺癌：紫金牛衍生的 4-羟基-2-甲氧基-6-十三烷基苯基乙酸酯作为有效的微管蛋白聚合抑制剂用于靶向胰腺导管腺癌治疗

The relationships among psychosocial impact, professional type, and vaccine hesitancy among healthcare workers during the COVID-19 pandemic

新冠疫情期间医护人员的心理社会影响、职业类型和疫苗犹豫之间的关系

Hydrogen sulfide coordinates glucose metabolism switch through destabilizing tetrameric pyruvate kinase M2

硫化氢通过破坏四聚体丙酮酸激酶M2的稳定性来协调葡萄糖代谢转换。

Systematic Studies on the Anti-SARS-CoV-2 Mechanisms of Tea Polyphenol-Related Natural Products

茶多酚类天然产物抗新冠病毒机制的系统研究

Neuron-derived neurotensin promotes pancreatic cancer invasiveness and gemcitabine resistance via the NTSR1/Akt pathway

神经元衍生的神经降压素通过 NTSR1/Akt 通路促进胰腺癌侵袭性和吉西他滨耐药性

Chromatin Remodeling-Related PRDM1 Increases Stomach Cancer Proliferation and Is Counteracted by Bromodomain Inhibitor

染色质重塑相关的 PRDM1 促进胃癌增殖，并被溴结构域抑制剂所抵消

Biomarker potential of nuclear Nrf2 activation in the ABC subtype of diffuse large B‑cell lymphoma

弥漫大 B 细胞淋巴瘤 ABC 亚型中核 Nrf2 激活的生物标志物潜力

Precise Control of Intracellular Trafficking and Receptor-Mediated Endocytosis in Living Cells and Behaving Animals

精确控制活细胞和行为动物中的细胞内运输和受体介导的内吞作用

The Prognosis Performance of a Neutrophil- and Lymphocyte-Associated Gene Mutation Score in a Head and Neck Cancer Cohort

中性粒细胞和淋巴细胞相关基因突变评分在头颈癌队列中的预后表现