日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Combined PARP14 inhibition and PD-1 blockade promotes cytotoxic T cell quiescence and modulates macrophage polarization in relapsed melanoma

PARP14抑制剂联合PD-1阻断可促进复发性黑色素瘤中细胞毒性T细胞的静止状态并调节巨噬细胞极化。

Rotem Leshem # ,Kieran Neil Sefton # ,Chun Wai Wong ,I-Hsuan Lin ,Dervla Tamara Isaac ,Mario Niepel ,Adam Hurlstone

Systemic immunosuppression from ultraviolet radiation exposure inhibits cancer immunotherapy

紫外线辐射引起的全身免疫抑制会抑制癌症免疫疗法。

Pedro Durao ,Timothy Budden ,Karthik Mallela ,Martha Gutteridge ,Isabella Mataloni ,Shilpa Gurung ,Mirco Mastrangelo ,Luke Roberts ,Antonia Banyard ,Garry Ashton ,Graham M Lord ,Adam Hurlstone ,Sara Valpione ,Amaya Viros

Transcriptome remodelling and changes in growth and cardiometabolic phenotype result following Grb10a knockdown in the early life of the zebrafish

在斑马鱼早期生命阶段敲低 Grb10a 基因会导致转录组重塑以及生长和心血管代谢表型的改变。

Evans, Bridget L; Garner, Terence; De Leonibus, Chiara; Wright, Lily; Sharps, Megan; Wearing, Oliver H; Ripley, Daniel M; Shiels, Holly A; Hurlstone, Adam F L; Clayton, Peter E; Stevens, Adam

Threshold uncertainty, early warning signals and the prevention of dangerous climate change

阈值不确定性、预警信号和预防危险的气候变化

Hurlstone, Mark J; White, Ben; Newell, Ben R

Transitory Schwann Cell Precursor and hybrid states underpin melanoma therapy resistance and metastasis.

短暂的雪旺细胞前体和混合状态是黑色素瘤治疗耐药性和转移的基础

Gopalan Vishaka, Wong Chun Wai, Leshem Rotem, Owen Luke, Vallius Tuulia, Shi Yingxiao, Jiang Yuhong, Pérez-Guijarro Eva, Wu Emily, Chin Sung, Ebersole Jessica, Smith Cari, Sassano Antonella, Constantino Maira Alves, Haley Michael J, Livak Ferenc, Simpson R Mark, Day Chi-Ping, Hurlstone Adam, Hannenhalli Sridhar, Merlino Glenn, Marie Kerrie L

A trafficking regulatory subnetwork governs αVβ6 integrin-HER2 cross-talk to control breast cancer invasion and drug resistance

运输调节子网络控制 αVβ6 整合素-HER2 串扰以控制乳腺癌侵袭和耐药性

Horacio Maldonado, Marcel Dreger, Lara D Bedgood, Theano Kyriakou, Katarzyna I Wolanska, Megan E Rigby, Valeria E Marotta, Justine M Webster, Jun Wang, Emma V Rusilowicz-Jones, John F Marshall, Judy M Coulson, Iain R Macpherson, Adam Hurlstone, Mark R Morgan

Thinking clearly about misinformation

冷静思考错误信息

Tay, Li Qian; Lewandowsky, Stephan; Hurlstone, Mark J; Kurz, Tim; Ecker, Ullrich K H

PARP14 inhibition restores PD-1 immune checkpoint inhibitor response following IFNγ-driven acquired resistance in preclinical cancer models

在临床前癌症模型中,PARP14抑制可恢复IFNγ驱动的获得性耐药后对PD-1免疫检查点抑制剂的反应。

Chun Wai Wong ,Christos Evangelou ,Kieran N Sefton # ,Rotem Leshem # ,Wei Zhang ,Vishaka Gopalan ,Sorayut Chattrakarn ,Macarena Lucia Fernandez Carro ,Erez Uzuner ,Holly Mole ,Daniel J Wilcock ,Michael P Smith ,Kleita Sergiou ,Brian A Telfer ,Dervla T Isaac ,Chang Liu ,Nicholas R Perl ,Kerrie Marie ,Paul Lorigan ,Kaye J Williams ,Patricia E Rao ,Raghavendar T Nagaraju ,Mario Niepel ,Adam F L Hurlstone

The role of IFN-γ-signalling in response to immune checkpoint blockade therapy

IFN-γ信号通路在免疫检查点阻断疗法中的作用

Wong, Chun Wai; Huang, Yang Yu; Hurlstone, Adam

A focus shift in the evaluation of misinformation interventions

评估虚假信息干预措施的重点转变

Tay, Li Qian; Lewandowsky, Stephan; Hurlstone, Mark J; Kurz, Tim; Ecker, Ullrich K H