日期 影响因子
日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:
–

Ustekinumab therapy for moderately to severely active pediatric Crohn's disease: UNITI Jr study safety and efficacy results in patients weighing at least 40 kg

乌司奴单抗治疗中重度活动性儿童克罗恩病：UNITI Jr 研究在体重至少 40 公斤的患者中的安全性和有效性结果

期刊:Journal of Crohns & Colitis
影响因子:8.7
doi:10.1093/ecco-jcc/jjag011
De Greef, Elisabeth; Turner, Dan; Kierkuś, Jarosław; Korczowski, Bartosz; Meglicka, Monika; Cohen, Stanley A; Hyams, Jeffrey S; Griffiths, Anne M; Rosh, Joel R; Strauss, Richard; Van Limbergen, Els; Adedokun, Omoniyi J; Kim, Lilianne; Volger, Sheri
克罗恩病
发表日期：2026
文献求助 收藏

Model-Informed Deep Q-Networks to Guide Infliximab Dosing in Pediatric Crohn's Disease

基于模型的深度Q网络指导儿童克罗恩病英夫利昔单抗给药

期刊:Clinical Pharmacology & Therapeutics
影响因子:5.5
doi:10.1002/cpt.70118
Irie, Kei; Minar, Phillip; Reifenberg, Jack; Boyle, Brendan M; Noe, Joshua D; Hyams, Jeffrey S; Mizuno, Tomoyuki
克罗恩病
发表日期：2026
文献求助 收藏

Short Ileal Microvillus Length Phenotype Associates with Progression from Inflammatory to Complicated Disease Behavior in Pediatric Crohn's Disease

回肠微绒毛长度短表型与儿童克罗恩病从炎症型向复杂性疾病进展相关

期刊:Inflammatory Bowel Diseases
影响因子:4.3
doi:10.1093/ibd/izaf288
Haberman, Yael; Braun, Tzipi; Karns, Rebekah; Bartel, Courtney A; Bonkowski, Erin; Simpson, Katherine F; Walters, Thomas D; Hyams, Jeffrey S; Liu, Ta-Chiang; Kugathasan, Subra; Denson, Lee A; VanDussen, Kelli L
克罗恩病
炎症/感染
炎症
发表日期：2026
文献求助 收藏

Reshaping study design for faster extrapolation-based drug approval in pediatric inflammatory bowel diseases: An ESPGHAN-NASPGHAN position paper

重塑研究设计以加快基于外推法的儿科炎症性肠病药物审批：ESPGHAN-NASPGHAN 立场文件

期刊:Journal of Pediatric Gastroenterology and Nutrition
影响因子:2.6
doi:10.1002/jpn3.70275
Turner, Dan; Assa, Amit; Malham, Mikkel; Bar-Asher, Shira Yuval; Rayan, Carla; Hyams, Jeffrey S; Uhlig, Holm H; Pasternak, Brad; Wilson, David C; Michel, Hilary K; de Ridder, Lissy; Zuckerman, Eric; Aloi, Marina; Szitanyi, Peter; Dubinsky, Marla C; Griffiths, Anne M; Saldana, Roberto; Martín-de-Carpi, Javier; Wine, Eytan; Russell, Richard K; Adler, Jeremy; Picoraro, Joseph
炎症/感染
炎症
发表日期：2026
文献求助 收藏

Machine Learning Modeling for Predicting Infliximab Pharmacokinetics in Pediatric and Young Adult Patients With Crohn Disease: Leveraging Ensemble Modeling With Synthetic and Real-World Data

利用机器学习模型预测英夫利昔单抗在克罗恩病患儿及青少年患者中的药代动力学：结合合成数据和真实世界数据的集成建模

期刊:Therapeutic Drug Monitoring
影响因子:2.4
doi:10.1097/FTD.0000000000001348
Irie, Kei; Minar, Phillip; Reifenberg, Jack; Boyle, Brendan M; Noe, Joshua D; Hyams, Jeffrey S; Mizuno, Tomoyuki
克罗恩病
发表日期：2026
文献求助 收藏

Hybrid Population Pharmacokinetic-Machine Learning Modeling to Predict Infliximab Pharmacokinetics in Pediatric and Young Adult Patients with Crohn's Disease

采用混合群体药代动力学-机器学习模型预测克罗恩病患儿及青少年患者的英夫利昔单抗药代动力学

期刊:Clinical Pharmacokinetics
影响因子:4
doi:10.1007/s40262-025-01564-7
Irie, Kei; Minar, Phillip; Reifenberg, Jack; Boyle, Brendan M; Noe, Joshua D; Hyams, Jeffrey S; Mizuno, Tomoyuki
克罗恩病
发表日期：2025
文献求助 收藏

Baseline terminal ileal CT and MRI measurements are associated with imaging outcomes in pediatric Crohn's disease: a cohort study

基线末端回肠CT和MRI测量值与儿童克罗恩病影像学结果相关：一项队列研究

期刊:Pediatric Radiology
影响因子:2.3
doi:10.1007/s00247-025-06302-6
Ta, Allison D; Dillman, Jonathan R; Ollberding, Nicholas J; Haberman, Yael; Baldassano, Robert; Markowitz, James; Otley, Anthony; Dotson, Jennifer L; Pfefferkorn, Marian; Hyams, Jeffrey S; Heyman, Melvin B; Kim, Sandra C; Noe, Joshua; Snapper, Scott; Alazraki, Adina; Kugathasan, Subra; Denson, Lee A
克罗恩病
发表日期：2025
文献求助 收藏

Hybrid Population PK-Machine Learning Modeling to Predict Infliximab Pharmacokinetics in Pediatric and Young Adult Patients with Crohn's Disease

采用混合群体药代动力学-机器学习模型预测克罗恩病患儿及青少年患者的英夫利昔单抗药代动力学

期刊:
影响因子:
doi:10.1101/2025.05.01.651780
Irie, Kei; Minar, Phillip; Reifenberg, Jack; Boyle, Brendan M; Noe, Joshua D; Hyams, Jeffrey S; Mizuno, Tomoyuki
克罗恩病
发表日期：2025
文献求助 收藏

Progression of Pediatric Crohn's Disease Is Associated With Anti-Tumor Necrosis Factor Timing and Body Mass Index Z-Score Normalization

儿童克罗恩病进展与抗肿瘤坏死因子治疗时机和体重指数Z评分正常化相关

期刊:Clinical Gastroenterology and Hepatology
影响因子:12
doi:10.1016/j.cgh.2023.08.042
Geem, Duke; Hercules, David; Pelia, Ranjit S; Venkateswaran, Suresh; Griffiths, Anne; Noe, Joshua D; Dotson, Jennifer L; Snapper, Scott; Rabizadeh, Shervin; Rosh, Joel R; Baldassano, Robert N; Markowitz, James F; Walters, Thomas D; Ananthakrishnan, Ashwin; Sharma, Garima; Denson, Lee A; Hyams, Jeffrey S; Kugathasan, Subra
肿瘤
克罗恩病
肿瘤免疫
发表日期：2024
文献求助 收藏

Fitness-for-use of Retrospective Multicenter Electronic Health Records to Conduct Outcome Analysis for Pediatric Ulcerative Colitis

利用回顾性多中心电子健康记录进行儿童溃疡性结肠炎结局分析的适用性

期刊:Medicine
影响因子:1.4
doi:10.1097/MD.0000000000037395
Wang, Zhu; Song, Xing; Waitman, Lemuel R; Hyams, Jeffrey S; Denson, Lee A
肠炎
结肠炎
发表日期：2024
文献求助 收藏