日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

The Spatial Extracellular Proteomic Tumor Microenvironment Distinguishes Molecular Subtypes of Hepatocellular Carcinoma

空间细胞外蛋白质组肿瘤微环境区分肝细胞癌的分子亚型

Jade K Macdonald, Harrison B Taylor, Mengjun Wang, Andrew Delacourt, Christin Edge, David N Lewin, Naoto Kubota, Naoto Fujiwara, Fahmida Rasha, Cesia A Marquez, Atsushi Ono, Shiro Oka, Kazuaki Chayama, Sara Lewis, Bachir Taouli, Myron Schwartz, M Isabel Fiel, Richard R Drake, Yujin Hoshida, Anand S

Intratumoral dendritic cell-CD4+ T helper cell niches enable CD8+ T cell differentiation following PD-1 blockade in hepatocellular carcinoma

肝细胞癌中,肿瘤内树突状细胞-CD4+ T辅助细胞微环境可促进PD-1阻断后CD8+ T细胞的分化。

Assaf Magen #,Pauline Hamon #,Nathalie Fiaschi,Brian Y Soong,Matthew D Park,Raphaël Mattiuz,Etienne Humblin,Leanna Troncoso,Darwin D'souza,Travis Dawson,Joel Kim,Steven Hamel,Mark Buckup,Christie Chang,Alexandra Tabachnikova,Hara Schwartz,Nausicaa Malissen,Yonit Lavin,Alessandra Soares-Schanoski,Bruno Giotti,Samarth Hegde,Giorgio Ioannou,Edgar Gonzalez-Kozlova,Clotilde Hennequin,Jessica Le Berichel,Zhen Zhao,Stephen C Ward,Isabel Fiel,Baijun Kou,Michael Dobosz,Lianjie Li,Christina Adler,Min Ni,Yi Wei,Wei Wang,Gurinder S Atwal,Kunal Kundu,Kamil J Cygan,Alexander M Tsankov,Adeeb Rahman,Colles Price,Nicolas Fernandez,Jiang He,Namita T Gupta,Seunghee Kim-Schulze,Sacha Gnjatic,Ephraim Kenigsberg,Raquel P Deering,Myron Schwartz,Thomas U Marron #,Gavin Thurston #,Alice O Kamphorst #,Miriam Merad #

Prolonged hypernutrition impairs TREM2-dependent efferocytosis to license chronic liver inflammation and NASH development

长期营养过剩会损害TREM2依赖性胞吞作用,从而导致慢性肝脏炎症和非酒精性脂肪性肝炎(NASH)的发生。

Xiaochen Wang ,Qifeng He ,Chuanli Zhou ,Yueyuan Xu ,Danhui Liu ,Naoto Fujiwara ,Naoto Kubota ,Arielle Click ,Polly Henderson ,Janiece Vancil ,Cesia Ammi Marquez ,Ganesh Gunasekaran ,Myron E Schwartz ,Parissa Tabrizian ,Umut Sarpel ,Maria Isabel Fiel ,Yarui Diao ,Beicheng Sun ,Yujin Hoshida ,Shuang Liang ,Zhenyu Zhong

The portrait of liver cancer is shaped by mitochondrial genetics

肝癌的特征受线粒体遗传学的影响

Mrittika Chattopadhyay ,Edmund Charles Jenkins ,Ana Victoria Lechuga-Vieco ,Kai Nie ,Maria Isabel Fiel ,Alexander Rialdi ,Ernesto Guccione ,Jose Antonio Enriquez ,Daniela Sia ,Amaia Lujambio ,Doris Germain

Erratum to "Giant pedunculated hepatocellular adenoma masquerading as a subdiaphragmatic mass: Diagnostic challenges of a rare tumor" [Radiology Case Reports 16 (2021) 84-89]

对“巨大带蒂肝细胞腺瘤伪装成膈下肿块:罕见肿瘤的诊断挑战”的勘误[放射学病例报告 16 (2021) 84-89]

Shafaee, Zahra; Liu, Shaojun; Isabel Fiel, Maria; Blue, Robert

N-Glycosylation Patterns Correlate with Hepatocellular Carcinoma Genetic Subtypes

N-糖基化模式与肝细胞癌基因亚型相关

Andrew DelaCourt, Alyson Black, Peggi Angel, Richard Drake, Yujin Hoshida, Amit Singal, David Lewin, Bachir Taouli, Sara Lewis, Myron Schwarz, M Isabel Fiel, Anand S Mehta

Repositioning of a novel GABA-B receptor agonist, AZD3355 (Lesogaberan), for the treatment of non-alcoholic steatohepatitis

重新定位新型 GABA-B 受体激动剂 AZD3355 (Lesogaberan),用于治疗非酒精性脂肪性肝炎

Dipankar Bhattacharya, Christine Becker, Benjamin Readhead, Nicolas Goossens, Jacqueline Novik, Maria Isabel Fiel, Leslie P Cousens, Björn Magnusson, Anna Backmark, Ryan Hicks, Joel T Dudley, Scott L Friedman0

Modeling dysbiosis of human NASH in mice: Loss of gut microbiome diversity and overgrowth of Erysipelotrichales

在小鼠中模拟人类 NASH 的菌群失调:肠道微生物群多样性丧失和丹毒丝菌过度生长

James K Carter, Dipankar Bhattacharya, Joshua N Borgerding, M Isabel Fiel, Jeremiah J Faith, Scott L Friedman

Mannose Phosphate Isomerase and Mannose Regulate Hepatic Stellate Cell Activation and Fibrosis in Zebrafish and Humans

甘露糖磷酸异构酶和甘露糖调节斑马鱼和人类肝星状细胞活化和纤维化

Charles DeRossi, Kathryn Bambino, Joshua Morrison, Isabel Sakarin, Carlos Villacorta-Martin, Changwen Zhang, Jillian L Ellis, M Isabel Fiel, Maria Ybanez, Youngmin A Lee, Kuan-Lin Huang, Chunyue Yin, Takuya F Sakaguchi, Scott L Friedman, Augusto Villanueva, Jaime Chu

HIV infection modulates IL-1β response to LPS stimulation through a TLR4-NLRP3 pathway in human liver macrophages

HIV 感染通过人类肝巨噬细胞中的 TLR4-NLRP3 通路调节 IL-1β 对 LPS 刺激的反应

Lumin Zhang, Arevik Mosoian, Myron E Schwartz, Sander S Florman, Ganesh Gunasekaran, Thomas Schiano, M Isabel Fiel, Wei Jiang, Qi Shen, Andrea D Branch, Meena B Bansal