Isabelle Gerin相关文献与解析，生知库 | 链接生命科学的每一步

Jean Jacobs # ，Hristiana Lyubenova # ，Sven Potelle ，Johannes Kopp ，Isabelle Gerin ，Wing Lee Chan ，Miguel Rodriguez de Los Santos ，Wiebke Hülsemann ，Martin A Mensah ，Valérie Cormier-Daire ，Marieke Joosten ，Hennie T Bruggenwirth ，Kyra E Stuurman ，Valancy Miranda ，Philippe M Campeau ，Lars Wittler ，Julie Graff ，Stefan Mundlos ，Daniel M Ibrahim ，Emile Van Schaftingen ，Björn Fischer-Zirnsak ，Uwe Kornak ，Nadja Ehmke ，Guido T Bommer

代谢

发表日期：2025

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PPARα-mediated lipid metabolism reprogramming supports anti-EGFR therapy resistance in head and neck squamous cell carcinoma

PPARα介导的脂质代谢重编程支持头颈部鳞状细胞癌的抗EGFR治疗耐药性

期刊:Nature Communications

影响因子:14.7

doi:10.1038/s41467-025-56675-3

Valentin Van den Bossche # ，Julie Vignau # ，Engy Vigneron # ，Isabella Rizzi ，Hannah Zaryouh ，An Wouters ，Jérôme Ambroise ，Steven Van Laere ，Simon Beyaert ，Raphaël Helaers ，Cédric van Marcke ，Lionel Mignion ，Elise Y Lepicard ，Bénédicte F Jordan ，Céline Guilbaud ，Olivier Lowyck ，Hajar Dahou ，Antonella Mendola ，Manon Desgres ，Léo Aubert ，Isabelle Gerin ，Guido T Bommer ，Romain Boidot ，Perrine Vermonden ，Aurélien Warnant ，Yvan Larondelle ，Jean-Pascal Machiels ，Olivier Feron ，Sandra Schmitz ，Cyril Corbet

ACAD10 and ACAD11 allow entry of 4-hydroxy fatty acids into β-oxidation

ACAD10 和 ACAD11 允许 4-羟基脂肪酸进入 β-氧化

期刊:Cellular and Molecular Life Sciences

影响因子:6.2

doi:10.1007/s00018-024-05397-8

Stéphanie Paquay, Julia Duraffourd, Marina Bury, Isaac P Heremans, Francesco Caligiore, Isabelle Gerin, Vincent Stroobant, Jean Jacobs, Aymeric Pinon, Julie Graff, Didier Vertommen, Emile Van Schaftingen, Joseph P Dewulf, Guido T Bommer

信号转导

发表日期：2024

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SUZ domain-containing proteins have multiple effects on nonsense-mediated decay target transcripts

含有SUZ结构域的蛋白质对无义介导衰变靶转录本具有多种影响

期刊:Journal of Biological Chemistry

影响因子:4

doi:10.1016/j.jbc.2023.105095

Mathias Halbout ,Marina Bury ,Aoife Hanet ,Isabelle Gerin ,Julie Graff ,Theodore Killian ,Laurent Gatto ,Didier Vertommen ,Guido T Bommer

发表日期：2023

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Parkinson's disease protein PARK7 prevents metabolite and protein damage caused by a glycolytic metabolite

帕金森病蛋白 PARK7 可防止糖酵解代谢物引起的代谢物和蛋白质损伤

期刊:Proceedings of the National Academy of Sciences of the United States of America

影响因子:

doi:10.1073/pnas.2111338119

Isaac P Heremans, Francesco Caligiore, Isabelle Gerin, Marina Bury, Marilena Lutz, Julie Graff, Vincent Stroobant, Didier Vertommen, Aurelio A Teleman, Emile Van Schaftingen, Guido T Bommer

ISPD produces CDP-ribitol used by FKTN and FKRP to transfer ribitol phosphate onto α-dystroglycan

ISPD 产生 CDP-核糖醇，FKTN 和 FKRP 利用该核糖醇磷酸盐将核糖醇转移到 α-肌营养不良聚糖上

期刊:Nature Communications

影响因子:14.7

doi:10.1038/ncomms11534

Isabelle Gerin, Benoît Ury, Isabelle Breloy, Céline Bouchet-Seraphin, Jennifer Bolsée, Mathias Halbout, Julie Graff, Didier Vertommen, Giulio G Muccioli, Nathalie Seta, Jean-Marie Cuisset, Ivana Dabaj, Susana Quijano-Roy, Ammi Grahn, Emile Van Schaftingen, Guido T Bommer

SRA regulates adipogenesis by modulating p38/JNK phosphorylation and stimulating insulin receptor gene expression and downstream signaling

SRA 通过调节 p38/JNK 磷酸化和刺激胰岛素受体基因表达和下游信号传导来调节脂肪生成

期刊:PLoS One

影响因子:2.9

doi:10.1371/journal.pone.0095416

Shannon Liu, Ruichuan Xu, Isabelle Gerin, William P Cawthorn, Ormond A Macdougald, Xiao-Wei Chen, Alan R Saltiel, Ronald J Koenig, Bin Xu

Expression of miR-33 from an SREBP2 intron inhibits cholesterol export and fatty acid oxidation

miR-33 在 SREBP2 内含子处的表达可抑制胆固醇输出和脂肪酸氧化

期刊:Journal of Biological Chemistry

影响因子:4

doi:10.1074/jbc.M110.152090

Isabelle Gerin, Laure-Alix Clerbaux, Olivier Haumont, Nicolas Lanthier, Arun K Das, Charles F Burant, Isabelle A Leclercq, Ormond A MacDougald, Guido T Bommer

信号转导

发表日期：2010

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Multiple roles for the non-coding RNA SRA in regulation of adipogenesis and insulin sensitivity

非编码 RNA SRA 在调节脂肪生成和胰岛素敏感性中的多种作用

期刊:PLoS One

影响因子:2.9

doi:10.1371/journal.pone.0014199

Bin Xu, Isabelle Gerin, Hongzhi Miao, Dang Vu-Phan, Craig N Johnson, Ruichuan Xu, Xiao-Wei Chen, William P Cawthorn, Ormond A MacDougald, Ronald J Koenig

Dax-1 and steroid receptor RNA activator (SRA) function as transcriptional coactivators for steroidogenic factor 1 in steroidogenesis

Dax-1 和类固醇受体 RNA 激活剂 (SRA) 在类固醇生成过程中作为类固醇生成因子 1 的转录辅激活剂发挥作用

期刊:Molecular and Cellular Biology

影响因子:3.2

doi:10.1128/MCB.01010-08

Bin Xu, Wei-Hsiung Yang, Isabelle Gerin, Chang-Deng Hu, Gary D Hammer, Ronald J Koenig

信号转导

发表日期：2009

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A missing enzyme-rescue metabolite as cause of a rare skeletal dysplasia

缺失的酶拯救代谢物是导致罕见骨骼发育不良的原因

PPARα-mediated lipid metabolism reprogramming supports anti-EGFR therapy resistance in head and neck squamous cell carcinoma

PPARα介导的脂质代谢重编程支持头颈部鳞状细胞癌的抗EGFR治疗耐药性

ACAD10 and ACAD11 allow entry of 4-hydroxy fatty acids into β-oxidation

ACAD10 和 ACAD11 允许 4-羟基脂肪酸进入 β-氧化

SUZ domain-containing proteins have multiple effects on nonsense-mediated decay target transcripts

含有SUZ结构域的蛋白质对无义介导衰变靶转录本具有多种影响

Parkinson's disease protein PARK7 prevents metabolite and protein damage caused by a glycolytic metabolite

帕金森病蛋白 PARK7 可防止糖酵解代谢物引起的代谢物和蛋白质损伤

ISPD produces CDP-ribitol used by FKTN and FKRP to transfer ribitol phosphate onto α-dystroglycan

ISPD 产生 CDP-核糖醇，FKTN 和 FKRP 利用该核糖醇磷酸盐将核糖醇转移到 α-肌营养不良聚糖上

SRA regulates adipogenesis by modulating p38/JNK phosphorylation and stimulating insulin receptor gene expression and downstream signaling

SRA 通过调节 p38/JNK 磷酸化和刺激胰岛素受体基因表达和下游信号传导来调节脂肪生成

Expression of miR-33 from an SREBP2 intron inhibits cholesterol export and fatty acid oxidation

miR-33 在 SREBP2 内含子处的表达可抑制胆固醇输出和脂肪酸氧化

Multiple roles for the non-coding RNA SRA in regulation of adipogenesis and insulin sensitivity

非编码 RNA SRA 在调节脂肪生成和胰岛素敏感性中的多种作用

Dax-1 and steroid receptor RNA activator (SRA) function as transcriptional coactivators for steroidogenic factor 1 in steroidogenesis

Dax-1 和类固醇受体 RNA 激活剂 (SRA) 在类固醇生成过程中作为类固醇生成因子 1 的转录辅激活剂发挥作用