日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Activation of osmo-sensitive LRRC8 anion channels in macrophages is important for micro-crystallin joint inflammation

巨噬细胞中渗透敏感的LRRC8阴离子通道的激活对微晶蛋白关节炎症很重要

Twinu Wilson Chirayath #, Matthias Ollivier #, Mete Kayatekin #, Isabelle Rubera, Chinh Nghia Pham, Jonas Friard, Nathalie Linck, Hélene Hirbec, Christèle Combes, Mylène Zarka, Frédéric Lioté, Pascal Richette, Francois Rassendren, Vincent Compan, Christophe Duranton, Hang Korng Ea

Renal Ischemia Tolerance Mediated by eIF5A Hypusination Inhibition Is Regulated by a Specific Modulation of the Endoplasmic Reticulum Stress

eIF5A 低肽化抑制介导的肾缺血耐受性受内质网应激的特定调节

Nicolas Melis, Isabelle Rubera, Sebastien Giraud, Marc Cougnon, Christophe Duranton, Mallorie Poet, Gisèle Jarretou, Raphaël Thuillier, Laurent Counillon, Thierry Hauet, Luc Pellerin, Michel Tauc, Didier F Pisani

Arterial Calcifications in Patients with Liver Cirrhosis Are Linked to Hepatic Deficiency of Pyrophosphate Production Restored by Liver Transplantation

肝硬化患者的动脉钙化与肝脏焦磷酸盐生成不足有关,而肝移植可以恢复这种不足。

Audrey Laurain ,Isabelle Rubera ,Micheline Razzouk-Cadet ,Stéphanie Bonnafous ,Miguel Albuquerque ,Valérie Paradis ,Stéphanie Patouraux ,Christophe Duranton ,Olivier Lesaux ,Georges Lefthériotis ,Albert Tran ,Rodolphe Anty ,Philippe Gual ,Antonio Iannelli ,Guillaume Favre

Relationships between Plasma Pyrophosphate, Vascular Calcification and Clinical Severity in Patients Affected by Pseudoxanthoma Elasticum

弹性纤维假黄瘤患者血浆焦磷酸盐和血管钙化与临床严重程度的关系

Georges Leftheriotis, Nastassia Navasiolava, Laetitia Clotaire, Christophe Duranton, Olivier Le Saux, Saïd Bendahhou, Audrey Laurain, Isabelle Rubera, Ludovic Martin

Inhibition of eIF5A hypusination reprogrammes metabolism and glucose handling in mouse kidney

抑制 eIF5A 低肽化可重新编程小鼠肾脏的代谢和葡萄糖处理

Marc Cougnon #, Romain Carcy #, Nicolas Melis, Isabelle Rubera, Christophe Duranton, Karine Dumas, Jean-François Tanti, Catherine Pons, Nicolas Soubeiran, Marina Shkreli, Thierry Hauet, Luc Pellerin, Sébastien Giraud, Nicolas Blondeau, Michel Tauc, Didier F Pisani

Proximal tubular epithelial insulin receptor mediates high-fat diet-induced kidney injury

近端肾小管上皮胰岛素受体介导高脂饮食引起的肾损伤

Hak Joo Lee ,Meenalakshmi M Mariappan ,Luke Norton ,Terry Bakewell ,Denis Feliers ,Sae Byeol Oh ,Andrew Donati ,Cherubina S Rubannelsonkumar ,Manjeri A Venkatachalam ,Stephen E Harris ,Isabelle Rubera ,Michel Tauc ,Goutam Ghosh Choudhury ,C Ronald Kahn ,Kumar Sharma ,Ralph A DeFronzo ,Balakuntalam S Kasinath

TMEM33 regulates intracellular calcium homeostasis in renal tubular epithelial cells

TMEM33 调节肾小管上皮细胞内钙稳态

Malika Arhatte, Gihan S Gunaratne, Charbel El Boustany, Ivana Y Kuo, Céline Moro, Fabrice Duprat, Magali Plaisant, Hélène Duval, Dahui Li, Nicolas Picard, Anais Couvreux, Christophe Duranton, Isabelle Rubera, Sophie Pagnotta, Sandra Lacas-Gervais, Barbara E Ehrlich, Jonathan S Marchant, Aaron M Sava

LRRC8/VRAC channels exhibit a noncanonical permeability to glutathione, which modulates epithelial-to-mesenchymal transition (EMT)

LRRC8/VRAC 通道对谷胱甘肽表现出非典型通透性,从而调节上皮-间质转化 (EMT)

Jonas Friard, Alain Corinus, Marc Cougnon, Michel Tauc, Didier F Pisani, Christophe Duranton, Isabelle Rubera

Targeting eIF5A Hypusination Prevents Anoxic Cell Death through Mitochondrial Silencing and Improves Kidney Transplant Outcome

靶向 eIF5A 低蛋白化可通过线粒体沉默防止缺氧细胞死亡并改善肾移植结果

Nicolas Melis, Isabelle Rubera, Marc Cougnon, Sébastien Giraud, Baharia Mograbi, Amine Belaid, Didier F Pisani, Stephan M Huber, Sandra Lacas-Gervais, Konstantina Fragaki, Nicolas Blondeau, Paul Vigne, Christian Frelin, Thierry Hauet, Christophe Duranton, Michel Tauc

Ablation of the Stimulatory G Protein α-Subunit in Renal Proximal Tubules Leads to Parathyroid Hormone-Resistance With Increased Renal Cyp24a1 mRNA Abundance and Reduced Serum 1,25-Dihydroxyvitamin D

肾近端小管中刺激性 G 蛋白 α 亚基的消融导致甲状旁腺激素抵抗,肾脏 CYP24A1 mRNA 丰度增加,血清 1,25-二羟基维生素 D 减少

Yan Zhu, Qing He, Cumhur Aydin, Isabelle Rubera, Michel Tauc, Min Chen, Lee S Weinstein, Vladimir Marshansky, Harald Jüppner, Murat Bastepe