日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Microbiota-derived indole-3-propionic acid extends lifespan in Drosophila and improves muscle and bone health in mice

肠道菌群来源的吲哚-3-丙酸可延长果蝇的寿命,并改善小鼠的肌肉和骨骼健康。

Vyavahare, Sagar; Berger, Ford; Swint, Shelton G; Mendhe, Bharati; Shukla, Mansi; Duchesne, Ian; Zhong, Roger; Cooley, Marion A; McGee-Lawrence, Meghan E; Isales, Carlos M; Hoffman, Jessica M; Fulzele, Sadanand

Tryptophan metabolites 3-hydroxykynurenine (3HK) and 3-hydroxyanthranilic acid (3HAA) increase oxidative stress and impair osteoblastic bone formation.

色氨酸代谢产物 3-羟基犬尿氨酸 (3HK) 和 3-羟基邻氨基苯甲酸 (3HAA) 会增加氧化应激并损害成骨细胞的骨形成。

Alhamad Dima W, Bensreti Husam, Ding Kehong, Sultana Shabiha, Yearwood Christopher L, Ellingwood Ashley, Shaver Joseph, Burkhart Kyle, Tripathi Alok, Dorn Jennifer, Cushing Michaela, Nesbit Hima, Dai Caihong, Morey Eric, Gross Colby, Alhamad Miar, Taylor Dylan, Cherezova Alena, Ilatovskaya Daria V, Zhi Wenbo, Cooley Marion A, Zhong Roger, Johnson Maribeth H, Bollag Wendy B, Hamrick Mark W, Fulzele Sadanand, Hill William D, Isales Carlos M, McGee-Lawrence Meghan E

Inhibition of AhR improves cortical bone and skeletal muscle function via preservation of neuromuscular junctions.

抑制 AhR 可通过保护神经肌肉接头来改善皮质骨和骨骼肌功能

Yu Kanglun, Vyavahare Sagar, Alhamad Dima, Bensreti Husam, Ruan Ling, Tuladhar Anik, Dai Caihong, Shaver Joseph C, Tripathi Alok, Ding Kehong, Pacholczyk Rafal, Cooley Marion A, Zhong Roger, Johnson Maribeth H, Chen Jie, Bollag Wendy B, Isales Carlos M, Hill William D, Hamrick Mark W, Fulzele Sadanand, McGee-Lawrence Meghan E

Sex-specific transcriptomic profiling reveals key players in bone loss associated with Alzheimer's disease

性别特异性转录组分析揭示了与阿尔茨海默病相关的骨质流失的关键因素

Gharpure, Mohini; Vyavahare, Sagar; Asante, Diana M; Chen, Jie; Zhong, Roger; Cooley, Marion A; Deak, Ferenc; Lu, Xin-Yun; Isales, Carlos M; Fulzele, Sadanand

Predictors of Fracture in Middle-Aged and Older Adults With Type 2 Diabetes and Overweight or Obesity

中老年人2型糖尿病合并超重或肥胖患者骨折的预测因素

Elam, Rachel E; Johnson, Karen C; Xu, Hongyan; Isales, Carlos M; Dong, Yanbin; Carbone, Laura D

Musculoskeletal Complications in COVID-19: Exploring the Role of Key Biomarkers

新冠肺炎的肌肉骨骼并发症:探索关键生物标志物的作用

Patel, Sagar; Foster, Cameron; Patel, Kamal; Hunter, Monte; Isales, Carlos M; Fulzele, Sadanand

Lipid metabolism in age-related musculoskeletal disorders: insights into sarcopenia and osteoporosis

与年龄相关的肌肉骨骼疾病中的脂质代谢:对肌肉减少症和骨质疏松症的见解

Lal, Shivum; Gunji, Shreya; Ahluwalia, Pankaj; Kolhe, Ravindra; Bollag, Wendy B; Hill, William D; McGee-Lawrence, Meghan E; Isales, Carlos M; Fulzele, Sadanand

Concentrations of adrenocorticotropic hormone too low to effect cortisol enhance osteogenesis in vitro and in vivo

促肾上腺皮质激素浓度过低而无法影响皮质醇水平时,可在体外和体内促进骨生成。

Tourkova, Irina L; Rankin, Reed A; Larrouture, Quitterie C; Dobrowolski, Steven F; Isales, Carlos M; Blair, Harry C

Transcriptional Signatures of Aerobic Exercise-Induced Muscle Adaptations in Humans

人类有氧运动诱导肌肉适应的转录特征

Iyer, Pranav; Asante, Diana M; Vyavahare, Sagar; Jin, Lee Tae; Ahluwalia, Pankaj; Kolhe, Ravindra; Kashyap, Hari; Isales, Carlos; Fulzele, Sadanand

Expression of the aryl hydrocarbon receptor in Osterix-lineage cells regulates adult skeletal homeostasis in a compartment-specific manner.

Osterix 谱系细胞中芳烃受体的表达以区室特异性的方式调节成年骨骼稳态

Dorn Jennifer, Alhamad Dima W, Bensreti Husam, Yearwood Christopher L, Allen Tate J, Cushing Michaela, Shaver Joseph C, Gross Colby, Whichard William C, Dai Caihong, Yu Kanglun, Zhong Roger, Cooley Marion A, Johnson Maribeth H, Bollag Wendy B, Fulzele Sadanand, Isales Carlos M, Hamrick Mark W, Hill William D, McGee-Lawrence Meghan E