日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Bruton's tyrosine kinase drives neuroinflammation and anxiogenic behavior in mouse models of stress

布鲁顿酪氨酸激酶在小鼠应激模型中引发神经炎症和焦虑行为

Simantini Ghosh, Zaidan Mohammed, Itender Singh

STAT3 inhibitor mitigates cerebral amyloid angiopathy and parenchymal amyloid plaques while improving cognitive functions and brain networks

STAT3 抑制剂可减轻脑淀粉样血管病和实质淀粉样斑块,同时改善认知功能和大脑网络

Jogender Mehla #, Itender Singh #, Deepti Diwan, James W Nelson, Molly Lawrence, Eunjae Lee, Adam Q Bauer, David M Holtzman, Gregory J Zipfel

cAMP regulated EPAC1 supports microvascular density, angiogenic and metastatic properties in a model of triple negative breast cancer

cAMP 调节的 EPAC1 在三阴性乳腺癌模型中支持微血管密度、血管生成和转移特性

Naveen Kumar, Peeyush Prasad, Eshna Jash, Smruthi Jayasundar, Itender Singh, Neyaz Alam, Nabendu Murmu, S P Somashekhar, Aaron Goldman, Seema Sehrawat

Minocycline protects against delayed cerebral ischemia after subarachnoid hemorrhage via matrix metalloproteinase-9 inhibition

米诺环素通过抑制基质金属蛋白酶-9来预防蛛网膜下腔出血后的迟发性脑缺血。

Vellimana, Ananth K; Zhou, Meng-Liang; Singh, Itender; Aum, Diane J; Nelson, James W; Harris, Glenn R; Athiraman, Umeshkumar; Han, Byung H; Zipfel, Gregory J

A novel fluorescent imaging technique for assessment of cerebral vasospasm after experimental subarachnoid hemorrhage

一种用于评估实验性蛛网膜下腔出血后脑血管痉挛的新型荧光成像技术

Diane J Aum, Ananth K Vellimana, Itender Singh, Eric Milner, James W Nelson, Byung Hee Han, Gregory J Zipfel

Heparan sulfate proteoglycans mediate Aβ-induced oxidative stress and hypercontractility in cultured vascular smooth muscle cells

硫酸肝素蛋白聚糖介导 Aβ 诱导的培养血管平滑肌细胞氧化应激和收缩过度

Matthew R Reynolds, Itender Singh, Tej D Azad, Brandon B Holmes, Phillip B Verghese, Hans H Dietrich, Marc Diamond, Guojun Bu, Byung Hee Han, Gregory J Zipfel

Contribution of reactive oxygen species to cerebral amyloid angiopathy, vasomotor dysfunction, and microhemorrhage in aged Tg2576 mice

活性氧对老年Tg2576小鼠脑淀粉样血管病、血管舒缩功能障碍和微出血的影响

Han, Byung Hee; Zhou, Meng-Liang; Johnson, Andrew W; Singh, Itender; Liao, Fan; Vellimana, Ananth K; Nelson, James W; Milner, Eric; Cirrito, John R; Basak, Jacob; Yoo, Min; Dietrich, Hans H; Holtzman, David M; Zipfel, Gregory Joseph

Impairment of glymphatic pathway function promotes tau pathology after traumatic brain injury

脑外伤后淋巴通路功能受损会促进 tau 病理

Jeffrey J Iliff, Michael J Chen, Benjamin A Plog, Douglas M Zeppenfeld, Melissa Soltero, Lijun Yang, Itender Singh, Rashid Deane, Maiken Nedergaard

Low levels of copper disrupt brain amyloid-β homeostasis by altering its production and clearance

低铜水平会通过改变β-淀粉样蛋白的生成和清除来破坏大脑β-淀粉样蛋白的稳态。

Singh, Itender; Sagare, Abhay P; Coma, Mireia; Perlmutter, David; Gelein, Robert; Bell, Robert D; Deane, Richard J; Zhong, Elaine; Parisi, Margaret; Ciszewski, Joseph; Kasper, R Tristan; Deane, Rashid

A lipoprotein receptor cluster IV mutant preferentially binds amyloid-β and regulates its clearance from the mouse brain

脂蛋白受体簇 IV 突变体优先结合淀粉样β蛋白并调节其从小鼠脑中的清除

Abhay P Sagare, Robert D Bell, Alaka Srivastava, Jesse D Sengillo, Itender Singh, Yoichiro Nishida, Nienwen Chow, Berislav V Zlokovic