日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Advanced Paternal Age Impacts Common Loci in the Sperm and Placenta DNA Methylomes

父亲高龄会影响精子和胎盘DNA甲基化组中的常见位点

Barnwell, Julia; Rahimi, Sophia; Jones, Sherri Lee; Chan, Donovan; Martel, Josée; Abdessamie, Sara; Herba, Catherine M; Séguin, Jean R; Fraser, William D; Greenwood, Celia M T; Nguyen, Tuong-Vi; Montreuil, Tina C; Trasler, Jacquetta

The Association between Long-Term DDT or DDE Exposures and an Altered Sperm Epigenome-a Cross-Sectional Study of Greenlandic Inuit and South African VhaVenda Men

长期接触 DDT 或 DDE 与精子表观基因组改变之间的关系 - 格陵兰因纽特人和南非 VhaVenda 男性的横断面研究

Ariane Lismer, Xiaojian Shao, Marie-Charlotte Dumargne, Christine Lafleur, Romain Lambrot, Donovan Chan, Gunnar Toft, Jens Peter Bonde, Amanda J MacFarlane, Riana Bornman, Natalie Aneck-Hahn, Sean Patrick, Janice M Bailey, Christiaan de Jager, Vanessa Dumeaux, Jacquetta M Trasler, Sarah Kimmins

Sperm DNA methylation defects in a new mouse model of the 5,10-methylenetetrahydrofolate reductase 677C>T variant and correction with moderate dose folic acid supplementation

5,10-亚甲基四氢叶酸还原酶677C>T变异小鼠模型中精子DNA甲基化缺陷及其通过中等剂量叶酸补充的纠正

Martínez Duncker Rebolledo, Edgar; Chan, Donovan; Christensen, Karen E; Reagan, Alaina M; Howell, Gareth R; Rozen, Rima; Trasler, Jacquetta

Sperm DNA methylome abnormalities occur both pre- and post-treatment in men with Hodgkin disease and testicular cancer

霍奇金淋巴瘤和睾丸癌患者在治疗前后均会出现精子DNA甲基化异常。

Chan, Donovan; Oros Klein, Kathleen; Riera-Escamilla, Antoni; Krausz, Csilla; O'Flaherty, Cristian; Chan, Peter; Robaire, Bernard; Trasler, Jacquetta M

Capturing sex-specific and hypofertility-linked effects of assisted reproductive technologies on the cord blood DNA methylome

捕捉辅助生殖技术对脐带血DNA甲基化组的性别特异性和低生育力相关影响

Rahimi, Sophia; Shao, Xiaojian; Chan, Donovan; Martel, Josée; Bérard, Anick; Fraser, William D; Simon, Marie-Michelle; Kwan, Tony; Bourque, Guillaume; Trasler, Jacquetta

Protective and sex-specific effects of moderate dose folic acid supplementation on the placenta following assisted reproduction in mice

中等剂量叶酸补充剂对小鼠辅助生殖后胎盘的保护作用及其性别特异性

Ihirwe, Rita Gloria; Martel, Josée; Rahimi, Sophia; Trasler, Jacquetta

Higher incidence of embryonic defects in mouse offspring conceived with assisted reproduction from fathers with sperm epimutations.

通过辅助生殖技术受孕的小鼠后代,其精子表观突变父亲所生的小鼠,胚胎缺陷发生率较高

Karahan Gurbet, Martel Josée, Rahimi Sophia, Farag Mena, Matias Fernando, MacFarlane Amanda J, Chan Donovan, Trasler Jacquetta

Prenatal paternal anxiety symptoms predict child DHEA levels and internalizing symptoms during adrenarche

父亲产前焦虑症状可预测儿童肾上腺功能初现期间的脱氢表雄酮 (DHEA) 水平和内化症状

Jones, Sherri Lee; De Braga, Victoria; Caccese, Christina; Lew, Jimin; Elgbeili, Guillaume; Castellanos-Ryan, Natalie; Parent, Sophie; Muckle, Gina; Herba, Catherine M; Fraser, William D; Ducharme, Simon; Barnwell, Julia; Trasler, Jacquetta; Séguin, Jean R; Nguyen, Tuong-Vi; Montreuil, Tina C

Exposure to environmental contaminants and folic acid supplementation intergenerationally impact fetal skeleton development through the paternal lineage in a rat model

在大鼠模型中,环境污染物暴露和叶酸补充剂通过父系遗传对胎儿骨骼发育产生代际影响。

L Charest, Phanie; Tessougue, Emmanuel; Lessard, Maryse; Herst, Pauline M; Navarro, Pauline; Kimmins, Sarah; Trasler, Jacquetta M; MacFarlane, Amanda J; Benoit-Biancamano, Marie-Odile; Bailey, Janice L; Dalvai, Mathieu

5,10-Methylenetetrahydrofolate reductase becomes phosphorylated during meiotic maturation in mouse oocytes

5,10-亚甲基四氢叶酸还原酶在小鼠卵母细胞减数分裂成熟过程中被磷酸化

Kyla Young, Allison K Tscherner, Baohua Zhang, Megan Meredith, Taylor McClatchie, Jacquetta M Trasler, Jay M Baltz