日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Imaging bioactive lipid isomers in acetaminophen-induced liver injury using nano-DESI tandem MS.

利用纳米DESI串联质谱对乙酰氨基酚引起的肝损伤中的生物活性脂质异构体进行成像。

Weigand Miranda R, Akakpo Jephte Yao, Hernly Emerson, Wali Syeda Nazifa, Zheng Aiming, Ramachandran Anup, Jaeschke Hartmut, Laskin Julia

Differential effects on acetaminophen-induced nephrotoxicity and liver injury following modulation of glutathione resynthesis

调节谷胱甘肽再合成对乙酰氨基酚引起的肾毒性和肝损伤产生不同的影响

Etemadi, Yasaman; Akakpo, Jephte Y; Fields, Timothy A; Ramachandran, Anup; Jaeschke, Hartmut

Reactive oxygen species and peroxynitrite in acetaminophen-induced liver injury: Lipid peroxidation and ferroptosis-like cell death

对乙酰氨基酚诱导的肝损伤中的活性氧和过氧亚硝酸盐:脂质过氧化和铁死亡样细胞死亡

Jaeschke, Hartmut; Ramachandran, Anup

Dysregulation of xenobiotic metabolism and mitochondrial dysfunction exacerbate acetaminophen-induced hepatotoxicity in human antigen R-deficient male mice

异生物质代谢紊乱和线粒体功能障碍会加剧人抗原R缺陷雄性小鼠对乙酰氨基酚诱导的肝毒性。

Eppler, Natalie; Jones, Elizabeth; Ahamed, Forkan; Raja, Naren; Akakpo, Jephte Y; Lebofsky, Margitta; He, Lily; Vats, Ira; Ghosh, Priyanka; Yu, Yifan; Thomas, Kaitlyn; McCoin, Colin; Thyfault, John; Wu, Xiaoqing; Xu, Liang; Cui, Wei; Wang, Rong; Jaeschke, Hartmut; Zhang, Yuxia

Understanding Liver and Digestive Diseases: A Paved Road to Improve Diagnosis, Management, and Treatment

了解肝脏和消化系统疾病:改善诊断、管理和治疗的铺平道路

Bergheim, Ina; Cadranel, Jean Francois; Chen, Jian Guo; Ding, Weng Xin; Eferl, Robert; Garcia-Ruiz, Carmen; Jaeschke, Hartmut; Kazerouni, Firouzeh; Lonardo, Amedeo; Mann, Derek A; Mendez-Sanchez, Nahum; Mokhtari, Camelia; Moshage, Han; Raggi, Chiara; Strnad, Pavel; Tirosh, Oren; Zougmore, Honoré Tegwende; Fernandez-Checa, Jose C

Iron supplementation switches mode of cell death to ferroptosis during acetaminophen-induced liver injury in mice rendering it resistant to N-acetylcysteine.

在对乙酰氨基酚引起的小鼠肝损伤期间,补充铁剂可将细胞死亡方式转变为铁死亡,从而使其对 N-乙酰半胱氨酸产生抗性。

Adelusi Olamide B, Venkatraman Aparna, Akakpo Jephte Y, Ramachandran Anup, Jaeschke Hartmut

Acetaminophen should be a critical reference hepatotoxin for evaluating human-relevant in vitro models

对乙酰氨基酚应作为评估与人体相关的体外模型的重要参考肝毒素。

Jaeschke, Hartmut; Ramachandran, Anup

Are New Approach Methodologies (NAMs) the Holy Grail of toxicology?

新方法论(NAMs)是毒理学的圣杯吗?

Jaeschke, Hartmut; Ramachandran, Anup

Mixed lineage kinase domain-like protein deficiency exacerbates early injury in a mouse model of acetaminophen hepatotoxicity.

混合谱系激酶结构域样蛋白缺乏会加剧对乙酰氨基酚肝毒性小鼠模型中的早期损伤

Sanchez-Guerrero Giselle, Umbaugh David S, Smith Sawyer H, Akakpo Jephte Y, Jaeschke Hartmut, Ramachandran Anup

Special Issue "Mechanistic and Prognostic Biomarkers in Liver Diseases"

特刊“肝脏疾病的机制和预后生物标志物”

Jaeschke, Hartmut; McGill, Mitchell R