日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Imaging bioactive lipid isomers in acetaminophen-induced liver injury using nano-DESI tandem MS.

利用纳米DESI串联质谱对乙酰氨基酚引起的肝损伤中的生物活性脂质异构体进行成像。

Weigand Miranda R, Akakpo Jephte Yao, Hernly Emerson, Wali Syeda Nazifa, Zheng Aiming, Ramachandran Anup, Jaeschke Hartmut, Laskin Julia

Differential effects on acetaminophen-induced nephrotoxicity and liver injury following modulation of glutathione resynthesis

调节谷胱甘肽再合成对乙酰氨基酚引起的肾毒性和肝损伤产生不同的影响

Etemadi, Yasaman; Akakpo, Jephte Y; Fields, Timothy A; Ramachandran, Anup; Jaeschke, Hartmut

Dysregulation of xenobiotic metabolism and mitochondrial dysfunction exacerbate acetaminophen-induced hepatotoxicity in human antigen R-deficient male mice

异生物质代谢紊乱和线粒体功能障碍会加剧人抗原R缺陷雄性小鼠对乙酰氨基酚诱导的肝毒性。

Eppler, Natalie; Jones, Elizabeth; Ahamed, Forkan; Raja, Naren; Akakpo, Jephte Y; Lebofsky, Margitta; He, Lily; Vats, Ira; Ghosh, Priyanka; Yu, Yifan; Thomas, Kaitlyn; McCoin, Colin; Thyfault, John; Wu, Xiaoqing; Xu, Liang; Cui, Wei; Wang, Rong; Jaeschke, Hartmut; Zhang, Yuxia

Socio-Economic Impacts of Childhood Sickle Cell Disease on Households in Lubumbashi: An Exploratory Mixed-Methods Study

儿童镰状细胞病对卢本巴希家庭的社会经济影响:一项探索性混合方法研究

Mjumbe, Criss Koba; Fataki, Deborah Mazuya; Mwanvua, Laetitia Ngongo; Kapala, Noemie Kisimba; Katumba, Virginie Mujinga; Munianji, Edouard Mbaya; Moliba, Jephte

Iron supplementation switches mode of cell death to ferroptosis during acetaminophen-induced liver injury in mice rendering it resistant to N-acetylcysteine.

在对乙酰氨基酚引起的小鼠肝损伤期间,补充铁剂可将细胞死亡方式转变为铁死亡,从而使其对 N-乙酰半胱氨酸产生抗性。

Adelusi Olamide B, Venkatraman Aparna, Akakpo Jephte Y, Ramachandran Anup, Jaeschke Hartmut

4-Methylpyrazole-mediated inhibition of cytochrome P450 2E1 protects renal epithelial cells, but not bladder cancer cells, from cisplatin toxicity.

4-甲基吡唑介导的细胞色素 P450 2E1 抑制作用可保护肾上皮细胞免受顺铂毒性,但不能保护膀胱癌细胞免受顺铂毒性

Akakpo Jephte Y, Abbott Erika, Woolbright Benjamin L, Ramachandran Anup, Schnellmann Rick G, Wallace Darren P, Taylor John A

Mixed lineage kinase domain-like protein deficiency exacerbates early injury in a mouse model of acetaminophen hepatotoxicity.

混合谱系激酶结构域样蛋白缺乏会加剧对乙酰氨基酚肝毒性小鼠模型中的早期损伤

Sanchez-Guerrero Giselle, Umbaugh David S, Smith Sawyer H, Akakpo Jephte Y, Jaeschke Hartmut, Ramachandran Anup

Clinically relevant therapeutic approaches against acetaminophen hepatotoxicity and acute liver failure

针对对乙酰氨基酚肝毒性和急性肝衰竭的临床相关治疗方法

Ramachandran, Anup; Akakpo, Jephte Y; Curry, Steven C; Rumack, Barry H; Jaeschke, Hartmut

The thrombopoietin mimetic JNJ-26366821 reduces the late injury and accelerates the onset of liver recovery after acetaminophen-induced liver injury in mice

促血小板生成素类似物JNJ-26366821可减轻对乙酰氨基酚诱导的小鼠肝损伤的后期损伤,并加速肝脏恢复。

Olamide B Adelusi ,Jephte Y Akakpo ,Gary Eichenbaum ,Ejaz Sadaff ,Anup Ramachandran ,Hartmut Jaeschke

Spatial analysis of renal acetaminophen metabolism and its modulation by 4-methylpyrazole with DESI mass spectrometry imaging

使用 DESI 质谱成像对肾脏对乙酰氨基酚代谢及其受 4-甲基吡唑调节进行空间分析

Jephte Yao Akakpo, Hernando Olivos, Bindesh Shrestha, Anthony Midey, Hartmut Jaeschke, Anup Ramachandran