Jerala相关文献与解析，生知库 | 链接生命科学的每一步

Self-assembling protein cages: from coiled-coil module to machine learning-driven de novo design of next-generation biomaterials

自组装蛋白质笼：从卷曲螺旋模块到机器学习驱动的下一代生物材料的从头设计

期刊:Materials Advances

影响因子:4.7

doi:10.1039/d5ma00792e

Gupta, Arvind Kumar; Esih, Hana; Gradišar, Helena; Jerala, Roman

发表日期：2026

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Beyond Dimerization: Harnessing Tetrameric Coiled-Coils for Nanostructure Assembly

超越二聚化：利用四聚体螺旋卷曲结构组装纳米结构

期刊:Angewandte Chemie-International Edition

影响因子:16.9

doi:10.1002/anie.202422075

Vidmar, Sara; Šmidlehner, Tamara; Aupič, Jana; Strmšek, Žiga; Ljubetič, Ajasja; Xiao, Fei; Hu, Guang; Liu, Chuan; Beck, Florian; Erdmann, Philipp S; Jerala, Roman

发表日期：2025

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Clustering of NLRP3 induced by membrane or protein scaffolds promotes inflammasome assembly

膜或蛋白支架诱导的NLRP3聚集促进炎症小体的组装

期刊:Nature Communications

影响因子:14.7

doi:10.1038/s41467-025-60277-4

Elvira Boršić,Taja Železnik Ramuta,Sara Orehek,Mateja Erdani Kreft,Matthias Geyer,Roman Jerala,Iva Hafner-Bratkovič

Programmable Protein-DNA Composite Nanostructures: from Nanostructure Construction to Protein-Induced Micro-Scale Material Self-Assembly and Functionalization

可编程蛋白质-DNA复合纳米结构：从纳米结构构建到蛋白质诱导的微尺度材料自组装和功能化

期刊:Small

影响因子:12.1

doi:10.1002/smll.202502060

Zhou, Weijun; Strmšek, Žiga; Snoj, Jaka; Škarabot, Miha; Jerala, Roman

发表日期：2025

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Ligand-induced assembly of antibody variable fragments for the chemical regulation of biological processes

配体诱导抗体可变片段组装用于生物过程的化学调控

期刊:Cell Chemical Biology

影响因子:6.6

doi:10.1016/j.chembiol.2025.01.007

Erik Rihtar ，Tina Fink ，Tina Lebar ，Duško Lainšček ，Živa Kolenc ，Lucija Kadunc Polajnar ，Roman Jerala

RNA trans-splicing to rescue Î²-catenin: A novel approach for treating CTNNB1-Haploinsufficiency disorder.

RNA 反式剪接拯救 β-catenin：治疗 CTNNB1 单倍体不足症的新方法

期刊:Molecular Therapy-Nucleic Acids

影响因子:6.1

doi:10.1016/j.omtn.2025.102680

Maruna Matea, SuÅ¡jan-Leite Petra, MeÅ¡ko Maja, MiroÅ¡eviÄ Å pela, Jerala Roman

发表日期：2025

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Targeting cystatin F activation enhances NK cell cytotoxicity in glioblastoma models

靶向胱抑素F激活可增强胶质母细胞瘤模型中NK细胞的细胞毒性

期刊:Frontiers in Immunology

影响因子:5.7

doi:10.3389/fimmu.2025.1708281

Emanuela Senjor ，Anamarija Habič ，Urban Švajger ，Ana Mitrović ，Matic Proj ，Andrej Porčnik ，Borut Prestor ，Miha Jerala ，Matic Bošnjak ，Stanislav Gobec ，Barbara Breznik ，Janko Kos ，Milica Perišić Nanut

Engineering chimeric PCSK9 for a vaccine against atherosclerosis.

构建嵌合型PCSK9用于抗动脉粥样硬化疫苗

期刊:Molecular Therapy-Methods & Clinical Development

影响因子:4.7

doi:10.1016/j.omtm.2025.101535

MalenÅ¡ek Å pela, LainÅ¡Äek DuÅ¡ko, Esih Hana, Orehek Sara, Fink Tina, Urbanc Anja Golob, Blinc AleÅ¡, Jerala Roman

Repurposing nuclear receptors for ligand-responsive liquid condensate formation and gene regulation

利用核受体调控配体响应性液态凝聚体的形成和基因表达

Identification and prioritisation of tumour antigen candidates from 79 glioblastoma transcriptomes

从79例胶质母细胞瘤转录组中鉴定和优先排序肿瘤抗原候选物

Self-assembling protein cages: from coiled-coil module to machine learning-driven de novo design of next-generation biomaterials

自组装蛋白质笼：从卷曲螺旋模块到机器学习驱动的下一代生物材料的从头设计

Beyond Dimerization: Harnessing Tetrameric Coiled-Coils for Nanostructure Assembly

超越二聚化：利用四聚体螺旋卷曲结构组装纳米结构

Clustering of NLRP3 induced by membrane or protein scaffolds promotes inflammasome assembly

膜或蛋白支架诱导的NLRP3聚集促进炎症小体的组装

Programmable Protein-DNA Composite Nanostructures: from Nanostructure Construction to Protein-Induced Micro-Scale Material Self-Assembly and Functionalization

可编程蛋白质-DNA复合纳米结构：从纳米结构构建到蛋白质诱导的微尺度材料自组装和功能化

Ligand-induced assembly of antibody variable fragments for the chemical regulation of biological processes

配体诱导抗体可变片段组装用于生物过程的化学调控

RNA trans-splicing to rescue Î²-catenin: A novel approach for treating CTNNB1-Haploinsufficiency disorder.

RNA 反式剪接拯救 β-catenin：治疗 CTNNB1 单倍体不足症的新方法

Targeting cystatin F activation enhances NK cell cytotoxicity in glioblastoma models

靶向胱抑素F激活可增强胶质母细胞瘤模型中NK细胞的细胞毒性

Engineering chimeric PCSK9 for a vaccine against atherosclerosis.

构建嵌合型PCSK9用于抗动脉粥样硬化疫苗