A modular strategy for extracellular vesicle-mediated CRISPR-Cas9 delivery through aptamer-based loading and UV-activated cargo release.
通过基于适配体的装载和紫外线激活的货物释放，实现细胞外囊泡介导的 CRISPR-Cas9 递送的模块化策略。
期刊:Nature Communications
影响因子:15.7
doi:10.1038/s41467-025-65995-3
Elsharkasy Omnia M, Hegeman Charlotte V, Driedonks Tom A P, Liang Xiuming, Lansweers Ivana, Cotugno Olaf L, de Groot Ingmar Y, de Wit Zoë E M N J, Garcia-Guerra Antonio, Moorman Niels J A, Boonstra Sjoerd H, Bosman Esmeralda D C, Lefferts Juliet W, de Voogt Willemijn S, François Jerney J, van Wesel Annet C W, El Andaloussi Samir, Schiffelers Raymond M, Kooijmans Sander A A, Mastrobattista Enrico, Vader Pieter, de Jong Olivier G
