日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Presenilin 1 E280A mutation induces dysfunctional astrocytic phenotype in menstrual stromal-derived astrocyte-like cells.

早老素 1 E280A 突变导致月经基质来源的星形胶质细胞样细胞出现功能障碍的星形胶质细胞表型。

Correa Natalia Quiroz, Mendivil-Perez Miguel, Velez-Pardo Carlos, Jimenez-Del-Rio Marlene, Quiroz-Correa Q

Induced Microglial-like Cells Derived from Familial and Sporadic Alzheimer's Disease Peripheral Blood Monocytes Show Abnormal Phagocytosis and Inflammatory Response to PSEN1 E280A Cholinergic-like Neurons.

源自家族性和散发性阿尔茨海默病外周血单核细胞的诱导小胶质细胞样细胞对 PSEN1 E280A 胆碱能样神经元表现出异常的吞噬作用和炎症反应

Soto-Mercado Viviana, Mendivil-Perez Miguel, Velez-Pardo Carlos, Jimenez-Del-Rio Marlene

Combination of Epigallocatechin-3-Gallate and Tramiprosate Prevent Accumulation of Intracellular Aβ and Dysfunctional Autophagy-Lysosomal Pathway at Earliest Stage of Transdifferentiation of Mesenchymal Stromal Cells into PSEN1 E280A Cholinergic-like Neurons.

表没食子儿茶素-3-没食子酸酯和曲美普罗酸酯的组合可防止间充质基质细胞向PSEN1 E280A胆碱能样神经元转分化早期阶段细胞内Aβ的积累和自噬-溶酶体途径的功能障碍

Soto-Mercado Viviana, Mendivil-Perez Miguel, Jimenez-Del-Rio Marlene, Velez-Pardo Carlos

PF-06447475 Molecule Attenuates the Neuropathology of Familial Alzheimer's and Coexistent Parkinson's Disease Markers in PSEN1 I416T Dopaminergic-like Neurons.

PF-06447475 分子可减轻 PSEN1 I416T 多巴胺能样神经元中家族性阿尔茨海默病和共存的帕金森病标志物的神经病理学

Quintero-Espinosa Diana Alejandra, Velez-Pardo Carlos, Jimenez-Del-Rio Marlene

Protective Effect of the LRRK2 Kinase Inhibition in Human Fibroblasts Bearing the Genetic Variant GBA1 K198E: Implications for Parkinson's Disease.

LRRK2激酶抑制剂对携带GBA1 K198E基因变异的人类成纤维细胞的保护作用:对帕金森病的启示

Perez-Abshana Laura Patricia, Mendivil-Perez Miguel, Velez-Pardo Carlos, Jimenez-Del-Rio Marlene

Parkinson's Disease Gene Screening in Familial Cases from Central and South America

中南美洲家族性帕金森病病例的基因筛查

Lorenzo-Betancor, Oswaldo; Mehta, Seysha; Ramchandra, Janvi; Mumuney, Sekinat; Schumacher-Schuh, Artur F; Cornejo-Olivas, Mario; Sarapura-Castro, Elison H; Torres, Luis; Inca-Martinez, Miguel A; Mazzetti, Pilar; Cosentino, Carlos; Micheli, Federico; Tumas, Vitor; Dieguez, Elena; Raggio, Victor; Borges, Vanderci; Ferraz, Henrique B; Chana-Cuevas, Pedro; Jimenez-Del-Rio, Marlene; Velez-Pardo, Carlos; Moreno, Sonia; Lopera, Francisco; Orozco-Velez, Jorge L; Muñoz-Ospina, Beatriz; Rieder, Carlos R M; Medina-Escobar, Alex; Yearout, Dora; Zabetian, Cyrus P; Mata, Ignacio F

LRRK2 Kinase Inhibitor PF-06447475 Protects Drosophila melanogaster against Paraquat-Induced Locomotor Impairment, Life Span Reduction, and Oxidative Stress

LRRK2 激酶抑制剂 PF-06447475 保护果蝇免受百草枯引起的运动障碍、寿命缩短和氧化应激

Diana A Quintero-Espinosa, Marlene Jimenez-Del-Rio, Carlos Velez-Pardo

Rotenone Induces a Neuropathological Phenotype in Cholinergic-like Neurons Resembling Parkinson's Disease Dementia (PDD)

鱼藤酮诱导胆碱能样神经元出现类似帕金森病痴呆 (PDD) 的神经病理表型

Daniela Giraldo-Berrio, Miguel Mendivil-Perez, Carlos Velez-Pardo, Marlene Jimenez-Del-Rio

The GBA1 K198E Variant Is Associated with Suppression of Glucocerebrosidase Activity, Autophagy Impairment, Oxidative Stress, Mitochondrial Damage, and Apoptosis in Skin Fibroblasts

GBA1 K198E 变体与抑制葡萄糖脑苷脂酶活性、自噬受损、氧化应激、线粒体损伤和皮肤成纤维细胞凋亡有关

Laura Patricia Perez-Abshana, Miguel Mendivil-Perez, Marlene Jimenez-Del-Rio, Carlos Velez-Pardo

Combination of Tramiprosate, Curcumin, and SP600125 Reduces the Neuropathological Phenotype in Familial Alzheimer Disease PSEN1 I416T Cholinergic-like Neurons

曲米普罗酸盐、姜黄素和 SP600125 的组合可降低家族性阿尔茨海默病 PSEN1 I416T 胆碱能样神经元的神经病理学表型

Nicolas Gomez-Sequeda, Marlene Jimenez-Del-Rio, Carlos Velez-Pardo