日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Obesity increases genomic instability at DNA repeat-mediated endogenous mutation hotspots

肥胖会增加 DNA 重复介导的内源性突变热点处的基因组不稳定性

Pallavi Kompella, Guliang Wang, Russell E Durrett, Yanhao Lai, Celeste Marin, Yuan Liu, Samy L Habib, John DiGiovanni, Karen M Vasquez

Phase 1 clinical trial evaluating safety, bioavailability, and gut microbiome with a combination of curcumin and ursolic acid in lipid enhanced capsules

期临床试验评估脂质增强胶囊中姜黄素和熊果酸的组合的安全性、生物利用度和肠道微生物群

Michael A Liss, Furkan Dursun, G Lavender Hackman, Mohamed I Gadallah, Achinto Saha, Chelsea A Friedman, Atul S Rathore, Preeti Chandra, James R White, Stefano Tiziani, John DiGiovanni

Cysteine depletion sensitizes prostate cancer cells to agents that enhance DNA damage and to immune checkpoint inhibition

半胱氨酸耗竭使前列腺癌细胞对增强 DNA 损伤的药物和免疫检查点抑制敏感

Achinto Saha #, Shengyuan Zhao #, Austin Kindall, Carly Wilder, Chelsea A Friedman, Rachel Clark, George Georgiou, Everett Stone, Dawit Kidane, John DiGiovanni

Enzymatic depletion of l-Met using an engineered human enzyme as a novel therapeutic strategy for melanoma

使用工程化人类酶来消耗 l-Met 作为黑色素瘤的新治疗策略

Carly S Wilder, Jennifer Chiou, Anna Battenhouse, Achinto Saha, Zhao Chen, Eunice Kim, Mohamed I Gadallah, Stefano Tiziani, George Georgiou, Everett Stone, John DiGiovanni

Automated AI Detection Tool for Ankle Fractures Using X-Rays and Smart Devices

利用X光和智能设备自动检测踝关节骨折的AI工具

Samargandi, Ramy; Le Nail, Louis-Romée; de Pinieux, Gonzague; Tallegas, Matthias; Miquelestorena-Standley, Elodie; Nassour, Nour; Acitores, Jose M; Jang, Caleb; Ranganathan, Noopur; Wolf, John; Kwon, John; DiGiovanni, Christopher W; Ashkani-Esfahani, Soheil

Association between Socioeconomic Status and Increased Postoperative Emergency Department Utilization following Ankle Fracture Surgery

社会经济地位与踝关节骨折手术后急诊就诊率增加之间的关联

Parvan, Kobra; Zamanzadeh, Vahid; Lakdizaji, Sima; Mousavi Shabestari, Mitra; Ogawa, Takahisa; Kwon, John; DiGiovanni, Christopher W; Guss, Daniel

Non-canonical role of Hippo tumor suppressor serine/threonine kinase 3 STK3 in prostate cancer

Hippo 肿瘤抑制因子丝氨酸/苏氨酸激酶 3 STK3 在前列腺癌中的非典型作用

Amelia U Schirmer, Lucy M Driver, Megan T Zhao, Carrow I Wells, Julie E Pickett, Sean N O'Bryne, Benjamin J Eduful, Xuan Yang, Lauren Howard, Sungyong You, Gayathri R Devi, John DiGiovanni, Stephen J Freedland, Jen-Tsan Chi, David H Drewry, Everardo Macias

CXCR4 and CXCR7 signaling promotes tumor progression and obesity-associated epithelial-mesenchymal transition in prostate cancer cells

CXCR4 和 CXCR7 信号促进前列腺癌细胞的肿瘤进展和肥胖相关的上皮-间质转化

Songyeon Ahn, Achinto Saha, Rachel Clark, Mikhail G Kolonin, John DiGiovanni

Inhibition of Fibroblast Growth Factor Receptor Attenuates UVB-Induced Skin Carcinogenesis

抑制成纤维细胞生长因子受体可减弱 UVB 诱发的皮肤致癌作用

Megha A Thakur, Alok R Khandelwal, Xin Gu, Okkyung Rho, Steve Carbajal, Rima A Kandula, John DiGiovanni, Cherie-Ann O Nathan

Metabolomics-based phenotypic screens for evaluation of drug synergy via direct-infusion mass spectrometry

基于代谢组学的表型筛选,通过直接输注质谱法评估药物协同作用

Xiyuan Lu, G Lavender Hackman, Achinto Saha, Atul Singh Rathore, Meghan Collins, Chelsea Friedman, S Stephen Yi, Fumio Matsuda, John DiGiovanni, Alessia Lodi, Stefano Tiziani