日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

SRS143 a semi-synthetic analogue of andrographolide against house dust mite induced allergic asthma

SRS143 是一种半合成的穿心莲内酯类似物,可用于治疗屋尘螨引起的过敏性哮喘

Tan, Chee Yi; Oshiogwe, Okwuofu Emmanuel; Saud, Anoosha; Ng, Hui Suan; Sagineedu, Sreenivasa Rao; Stanslas, Johnson; Lim, Jonathan Chee Woei

Microglial Autophagy and Mitophagy in Ischemic Stroke: From Dual Roles to Therapeutic Modulation

缺血性卒中中的小胶质细胞自噬和线粒体自噬:从双重作用到治疗调控

Wu, Juan; Liu, Jiaxin; Li, Yanwen; Du, Fang; Li, Weijia; Thilakavathy, Karuppiah; Lim, Jonathan Chee Woei; Sun, Zhong; Deng, Juqing

Copper chelation redirects neutrophil function to enhance anti-GD2 antibody therapy in neuroblastoma

铜螯合可改变中性粒细胞功能,从而增强抗GD2抗体在神经母细胞瘤中的疗效

Jourdin R C Rouaen ,Antonietta Salerno ,Tyler Shai-Hee ,Jayne E Murray ,Giulia Castrogiovanni ,Charlotte McHenry ,Toni Rose Jue ,Vu Pham ,Jessica Lilian Bell ,Ensieh Poursani ,Emanuele Valli ,Riccardo Cazzoli ,Naomi Damstra ,Delia J Nelson ,Kofi L P Stevens ,Jonathan Chee ,Iveta Slapetova ,Maria Kasherman ,Renee Whan ,Francis Lin ,Blake J Cochran ,Nicodemus Tedla ,Feyza Colakoglu Veli ,Aysen Yuksel ,Chelsea Mayoh ,Federica Saletta ,Daniele Mercatelli ,Tatyana Chtanova ,Arutha Kulasinghe ,Daniel Catchpoole ,Giuseppe Cirillo ,Maté Biro ,Holger N Lode ,Fabio Luciani ,Michelle Haber ,Juliet C Gray ,Toby N Trahair ,Orazio Vittorio

An Andrographis paniculata Burm. Nees extract standardized for three main Andrographolides prevents house dust mite-induced airway inflammation, remodeling, and hyperreactivity by regulating Th1/Th2 gene expression in mice

穿心莲提取物标准化了三种主要穿心莲内酯,通过调节小鼠 Th1/Th2 基因表达来预防屋尘螨引起的呼吸道炎症、重塑和过度反应

Ibrahim Sulaiman, Emmanuel Oshiogwe Okwuofu, Norhafizah Mohtarrudin, Jonathan Chee Woei Lim, Johnson Stanslas

Targeting Inflammation in Non-Small Cell Lung Cancer through Drug Repurposing

通过药物再利用靶向非小细胞肺癌的炎症反应

Rajasegaran, Thiviyadarshini; How, Chee Wun; Saud, Anoosha; Ali, Azhar; Lim, Jonathan Chee Woei

Interferons limit autoantigen-specific CD8+ T-cell expansion in the non-obese diabetic mouse

干扰素限制非肥胖糖尿病小鼠自身抗原特异性 CD8+ T 细胞扩增

Gaurang Jhala, Balasubramanian Krishnamurthy, Thomas C Brodnicki, Tingting Ge, Satoru Akazawa, Claudia Selck, Prerak M Trivedi, Evan G Pappas, Leanne Mackin, Nicola Principe, Erwan Brémaud, David J De George, Louis Boon, Ian Smyth, Jonathan Chee, Thomas W H Kay, Helen E Thomas

Tumour draining lymph node-generated CD8 T cells play a role in controlling lung metastases after a primary tumour is removed but not when adjuvant immunotherapy is used

肿瘤引流淋巴结产生的 CD8 T 细胞在原发性肿瘤切除后在控制肺转移中发挥作用,但在使用辅助免疫疗法时则不起作用

Vanessa S Fear, Catherine A Forbes, Samuel A Neeve, Scott A Fisher, Jonathan Chee, Jason Waithman, Shao Kang Ma, Richard Lake, Anna K Nowak, Jenette Creaney, Matthew D Brown, Christobel Saunders, Bruce W S Robinson

Glycyrrhizic Acid: A Natural Plant Ingredient as a Drug Candidate to Treat COVID-19

甘草酸:一种天然植物成分,有望成为治疗新冠肺炎的候选药物

Sun, Zhong; He, Guozhong; Huang, Ninghao; Thilakavathy, Karuppiah; Lim, Jonathan Chee Woei; Kumar, S Suresh; Xiong, Chenglong

Characterization of neoantigen-specific T cells in cancer resistant to immune checkpoint therapies

对免疫检查点疗法有抗性的癌症中新抗原特异性 T 细胞的表征

Shamin Li, Yannick Simoni, Summer Zhuang, Austin Gabel, Shaokang Ma, Jonathan Chee, Laura Islas, Anthony Cessna, Jenette Creaney, Robert K Bradley, Alec Redwood, Bruce W Robinson, Evan W Newell

LRG1 Promotes Metastatic Dissemination of Melanoma through Regulating EGFR/STAT3 Signalling

LRG1通过调节EGFR / STAT3信号传导促进黑色素瘤的转移性播散

Yuet Ping Kwan, Melissa Hui Yen Teo, Jonathan Chee Woei Lim, Michelle Siying Tan, Graciella Rosellinny, Walter Wahli, Xiaomeng Wang