日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Constitutive activation and oncogenicity are mediated by loss of helical structure at the cytosolic boundary of thrombopoietin receptor mutant dimers

血小板生成素受体突变二聚体的胞质边界处螺旋结构的丧失介导了组成性激活和致癌性

Jean-Philippe Defour #, Emilie Leroy #, Sharmila Dass #, Thomas Balligand, Gabriel Levy, Ian C Brett, Nicolas Papadopoulos, Céline Mouton, Lidvine Genet, Christian Pecquet, Judith Staerk, Steven O Smith, Stefan N Constantinescu

Rapid genome editing by CRISPR-Cas9-POLD3 fusion

通过 CRISPR-Cas9-POLD3 融合进行快速基因组编辑

Ganna Reint #, Zhuokun Li #, Kornel Labun, Salla Keskitalo, Inkeri Soppa, Katariina Mamia, Eero Tolo, Monika Szymanska, Leonardo A Meza-Zepeda, Susanne Lorenz, Artur Cieslar-Pobuda, Xian Hu, Diana L Bordin, Judith Staerk, Eivind Valen, Bernhard Schmierer, Markku Varjosalo, Jussi Taipale, Emma Haapan

The kinase PERK and the transcription factor ATF4 play distinct and essential roles in autophagy resulting from tunicamycin-induced ER stress

激酶PERK和转录因子ATF4在衣霉素诱导的内质网应激引起的自噬中发挥着独特而重要的作用。

Morten Luhr ,Maria Lyngaas Torgersen ,Paula Szalai ,Adnan Hashim ,Andreas Brech ,Judith Staerk ,Nikolai Engedal

Targeted Metabolic Profiling of Methionine Cycle Metabolites and Redox Thiol Pools in Mammalian Plasma, Cells and Urine

哺乳动物血浆、细胞和尿液中蛋氨酸循环代谢物和氧化还原硫醇池的靶向代谢分析

Sidney Behringer, Victoria Wingert, Victor Oria, Anke Schumann, Sarah Grünert, Artur Cieslar-Pobuda, Stefan Kölker, Ann-Kathrin Lederer, Donald W Jacobsen, Judith Staerk, Oliver Schilling, Ute Spiekerkoetter, Luciana Hannibal

A drug-inducible transgenic system for direct reprogramming of multiple somatic cell types

用于直接重编程多种体细胞类型的药物诱导转基因系统

Marius Wernig, Christopher J Lengner, Jacob Hanna, Michael A Lodato, Eveline Steine, Ruth Foreman, Judith Staerk, Styliani Markoulaki, Rudolf Jaenisch