日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Validation of a functional human AD model with four AD therapeutics utilizing patterned ipsc-derived cortical neurons integrated with microelectrode arrays

利用与微电极阵列集成的模式化 ipsc 衍生皮质神经元,验证具有四种 AD 疗法的功能性人类 AD 模型

Julbert Caneus #, Kaveena Autar #, Nesar Akanda, Marcella Grillo, Christopher J Long, Max Jackson, Sarah Lindquist, Xiufang Guo, Dave Morgan, James J Hickman

Validation of a functional human AD model with four AD therapeutics utilizing patterned iPSC-derived cortical neurons integrated with microelectrode arrays

利用与微电极阵列集成的模式化 iPSC 衍生皮质神经元,验证具有四种 AD 疗法的功能性人类 AD 模型

Julbert Caneus, Kaveena Autar, Nesar Akanda, Marcella Grillo, Chris Long, Max Jackson, Sarah Lindquist, Xiufang Guo, Dave Morgan, James J Hickman

A functional hiPSC-cortical neuron differentiation and maturation model and its application to neurological disorders

功能性hiPSC-皮层神经元分化和成熟模型及其在神经系统疾病中的应用

Autar, Kaveena; Guo, Xiufang; Rumsey, John W; Long, Christopher J; Akanda, Nesar; Jackson, Max; Narasimhan, Narasimhan S; Caneus, Julbert; Morgan, Dave; Hickman, James J

A human induced pluripotent stem cell-derived cortical neuron human-on-a chip system to study Aβ42 and tau-induced pathophysiological effects on long-term potentiation

人类诱导性多能干细胞衍生的皮质神经元人芯片系统,用于研究 Aβ42 和 tau 诱导的长期增强病理生理影响

Julbert Caneus, Nesar Akanda, John W Rumsey, Xiufang Guo, Max Jackson, Christopher J Long, Frank Sommerhage, Sanya Georgieva, Nicholas M Kanaan, David Morgan, James J Hickman

Chromosome Instability and Mosaic Aneuploidy in Neurodegenerative and Neurodevelopmental Disorders

神经退行性疾病和神经发育障碍中的染色体不稳定性和嵌合型非整倍体

Potter, Huntington; Chial, Heidi J; Caneus, Julbert; Elos, Mihret; Elder, Nina; Borysov, Sergiy; Granic, Antoneta

Mitotic defects lead to neuronal aneuploidy and apoptosis in frontotemporal lobar degeneration caused by MAPT mutations

有丝分裂缺陷导致 MAPT 突变引起的额颞叶变性中神经元非整倍体和细胞凋亡

Julbert Caneus, Antoneta Granic, Rosa Rademakers, Dennis W Dickson, Christina M Coughlan, Heidi J Chial, Huntington Potter

Role of Trisomy 21 Mosaicism in Sporadic and Familial Alzheimer's Disease

21三体嵌合体在散发性和家族性阿尔茨海默病中的作用

Potter, Huntington; Granic, Antoneta; Caneus, Julbert

The Clinical Neuropsychiatry of Multiple Sclerosis

多发性硬化症的临床神经精神病学

Hu, Victor H; Harding-Esch, Emma M; Burton, Matthew J; Bailey, Robin L; Kadimpeul, Julbert; Mabey, David C W; MARKOVA, I