MSK1 promotes colorectal cancer metastasis by increasing Snail protein stability through USP5-mediated Snail deubiquitination.
MSK1 通过 USP5 介导的 Snail 去泛素化增加 Snail 蛋白的稳定性,从而促进结直肠癌转移
期刊:Experimental and Molecular Medicine
影响因子:12.9
doi:10.1038/s12276-025-01433-0
Hong Keun-Seok, Ryu Ki-Jun, Kim Hyemin, Kim Minju, Park Seung-Ho, Kim Taeyoung, Yang Jung Wook, Hwangbo Cheol, Kim Kwang Dong, Park Young-Jun, Yoo Jiyun