日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

The role of quiescent thymic progenitors in TAL/LMO2-induced T-ALL chemotolerance

静止胸腺祖细胞在 TAL/LMO2 诱导的 T-ALL 化学耐受性中的作用

Kevin W O'Connor, Kensei Kishimoto, Irena O Kuzma, Kelsey P Wagner, Jonathan S Selway, Justine E Roderick, Keshab K Karna, Kayleigh M Gallagher, Kai Hu, Haibo Liu, Rui Li, Michael A Brehm, Lihua Julie Zhu, David J Curtis, Cedric S Tremblay, Michelle A Kelliher

ZBP1 activation triggers hematopoietic stem and progenitor cell death resulting in bone marrow failure in mice

ZBP1 激活引发造血干细胞和祖细胞死亡,导致小鼠骨髓衰竭

Justine E Roderick-Richardson #, Sung-Eun Lim #, Sakiko Suzuki, Mohd Hafiz Ahmad, Jonathan Selway, Reem Suleiman, Keshab Karna, Jesse Lehman, Joanne O'Donnell, Lucio H Castilla, Jonathan Maelfait, Jan Rehwinkel, Michelle A Kelliher

RIP kinase 1-dependent endothelial necroptosis underlies systemic inflammatory response syndrome

RIP 激酶 1 依赖性内皮细胞坏死凋亡是全身炎症反应综合征的基础

Matija Zelic, Justine E Roderick, Joanne A O'Donnell, Jesse Lehman, Sung Eun Lim, Harish P Janardhan, Chinmay M Trivedi, Manolis Pasparakis, Michelle A Kelliher

Dendritic Cell RIPK1 Maintains Immune Homeostasis by Preventing Inflammation and Autoimmunity

树突状细胞 RIPK1 通过预防炎症和自身免疫来维持免疫稳态

Joanne A O'Donnell, Jesse Lehman, Justine E Roderick, Dalia Martinez-Marin, Matija Zelic, Ciara Doran, Nicole Hermance, Stephen Lyle, Manolis Pasparakis, Katherine A Fitzgerald, Ann Marshak-Rothstein, Michelle A Kelliher

RUNX1 is required for oncogenic Myb and Myc enhancer activity in T-cell acute lymphoblastic leukemia

RUNX1 是 T 细胞急性淋巴细胞白血病中致癌 Myb 和 Myc 增强子活性所必需的

AHyun Choi, Anuradha Illendula, John A Pulikkan, Justine E Roderick, Jessica Tesell, Jun Yu, Nicole Hermance, Lihua Julie Zhu, Lucio H Castilla, John H Bushweller, Michelle A Kelliher

BET Bromodomain Proteins Function as Master Transcription Elongation Factors Independent of CDK9 Recruitment

BET 溴结构域蛋白作为主转录延伸因子发挥作用,不依赖于 CDK9 募集

Georg E Winter, Andreas Mayer, Dennis L Buckley, Michael A Erb, Justine E Roderick, Sarah Vittori, Jaime M Reyes, Julia di Iulio, Amanda Souza, Christopher J Ott, Justin M Roberts, Rhamy Zeid, Thomas G Scott, Joshiawa Paulk, Kate Lachance, Calla M Olson, Shiva Dastjerdi, Sophie Bauer, Charles Y Lin,

Mdm2 Phosphorylation Regulates Its Stability and Has Contrasting Effects on Oncogene and Radiation-Induced Tumorigenesis

Mdm2 磷酸化调节其稳定性并对致癌基因和辐射诱导的肿瘤发生产生对比影响

Michael I Carr, Justine E Roderick, Hugh S Gannon, Michelle A Kelliher, Stephen N Jones

Phosphorylation of the Mdm2 oncoprotein by the c-Abl tyrosine kinase regulates p53 tumor suppression and the radiosensitivity of mice

c-Abl 酪氨酸激酶对 Mdm2 癌蛋白的磷酸化可调节 p53 肿瘤抑制和小鼠的放射敏感性

Michael I Carr, Justine E Roderick, Hong Zhang, Bruce A Woda, Michelle A Kelliher, Stephen N Jones

RNA G-quadruplexes cause eIF4A-dependent oncogene translation in cancer

RNA G-四链体导致癌症中 eIF4A 依赖性致癌基因翻译

Andrew L Wolfe, Kamini Singh, Yi Zhong, Philipp Drewe, Vinagolu K Rajasekhar, Viraj R Sanghvi, Konstantinos J Mavrakis, Man Jiang, Justine E Roderick, Joni Van der Meulen, Jonathan H Schatz, Christina M Rodrigo, Chunying Zhao, Pieter Rondou, Elisa de Stanchina, Julie Teruya-Feldstein, Michelle A Kel

An epigenetic mechanism of resistance to targeted therapy in T cell acute lymphoblastic leukemia

细胞急性淋巴细胞白血病靶向治疗耐药的表观遗传机制

Birgit Knoechel, Justine E Roderick, Kaylyn E Williamson, Jiang Zhu, Jens G Lohr, Matthew J Cotton, Shawn M Gillespie, Daniel Fernandez, Manching Ku, Hongfang Wang, Federica Piccioni, Serena J Silver, Mohit Jain, Daniel Pearson, Michael J Kluk, Christopher J Ott, Leonard D Shultz, Michael A Brehm, D