日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

KRASG12R-Mutant Pancreatic Cancer Features Limited ERK/MAPK Transcriptional Activity and a Distinctive Tumor Microenvironment

KRASG12R突变型胰腺癌具有ERK/MAPK转录活性受限和独特的肿瘤微环境。

Burge, Rachel A; Le Roux, Ozgun; Popow, Olesja; Spadafora, Victoria K; Rajesh, Christabelle; Adair, Sara J; Bialousow, Lucas; Murphy, Cailey; Saberi, Samaneh; Vaena, Silvia G; Taquey, Margaret C; Allen, Sarah; Han, Lu; Helke, Kristi L; Sharma, Sudarshana; Ostrowski, Michael C; Guttridge, Denis C; Dincman, Toros A; Bauer, Todd W; Kashatus, David F; McFall, Thomas; Haigis, Kevin M; Hollingsworth, Michael A; Counter, Christopher M; Der, Channing J; Hobbs, G Aaron

De novo design of protein binders that target DELE1 to inhibit the mitochondrial stress response

从头设计靶向 DELE1 的蛋白质结合剂,以抑制线粒体应激反应

Yang, Rui; Zheng, Kaiyuan; Metts, McGuire; Wang, Yiluo; Yin, Danyan; Li, Kevin P; Prazmowska, Agnieszka A; Kashatus, David F; Kuhlman, Brian; Yang, Jie

PTEN Oxidation Promotes Constitutive PI3K Signaling and Inducible Macropinocytosis in Pancreatic Cancer

PTEN氧化促进胰腺癌中组成型PI3K信号传导和诱导型巨胞饮作用

Burge, Rachel A; Bialousow, Lucas; Linke, Amanda J; Coalson, Hannah S; Adair, Sara J; Sundararaj, Kamala; Smith, Merissa; Bumbleburg, Cameron; Bauer, Todd W; Kashatus, David F; Hobbs, G Aaron

NRF2 regulates lipid droplet dynamics to prevent lipotoxicity.

NRF2 调节脂滴动态以防止脂毒性

Prevost Christopher T, Gansereit William B, Kashatus David F

Spatial regulation of mitochondrial membrane potential by α5β1 integrin engagement in collective cell migration.

α5β1整合素参与细胞集体迁移,从而对线粒体膜电位进行空间调控

Pacheco Gustavo G, Dzamba Bette J, Endo Wakako, Edwards Benjamin C, Khan Minah, Comlekoglu Tien, Shook David R, Quasey Keri, Bjerke Maureen A, Hirsh Glen D, Kashatus David F, DeSimone Douglas W

HSP70-mediated mitochondrial dynamics and autophagy represent a novel vulnerability in pancreatic cancer

HSP70介导的线粒体动力学和自噬代表了胰腺癌的一种新的脆弱性

Ferretti, Giulia D S; Quaas, Colleen E; Bertolini, Irene; Zuccotti, Alessandro; Saatci, Ozge; Kashatus, Jennifer A; Sharmin, Salma; Lu, David Y; Poli, Adi Narayana Reddy; Quesnelle, Abigail F; Rodriguez-Blanco, Jezabel; de Cubas, Aguirre A; Hobbs, G Aaron; Liu, Qin; O'Bryan, John P; Salvino, Joseph M; Kashatus, David F; Sahin, Ozgur; Barnoud, Thibaut

Mitochondrial dynamics in cancer stem cells

癌症干细胞中的线粒体动力学

Sessions, Dane T; Kashatus, David F

miR-206 family is important for mitochondrial and muscle function, but not essential for myogenesis in vitro

miR-206 家族对线粒体和肌肉功能很重要,但对体外肌肉生成并非必不可少

Roza K Przanowska, Ewelina Sobierajska, Zhangli Su, Kate Jensen, Piotr Przanowski, Sarbajeet Nagdas, Jennifer A Kashatus, David F Kashatus, Sanchita Bhatnagar, John R Lukens, Anindya Dutta

Mito Hacker: a set of tools to enable high-throughput analysis of mitochondrial network morphology

Mito Hacker:一套用于高通量分析线粒体网络形态的工具

Rohani, Ali; Kashatus, Jennifer A; Sessions, Dane T; Sharmin, Salma; Kashatus, David F

RalA and RalB relocalization to depolarized mitochondria depends on clathrin-mediated endocytosis and facilitates TBK1 activation

RalA 和 RalB 向去极化线粒体的重新定位依赖于网格蛋白介导的内吞作用,并促进 TBK1 的激活。

Sarah R Pollock ,Austin R Schinlever ,Ali Rohani ,Jennifer A Kashatus ,David F Kashatus