HLA matching or CRISPR editing of HLA class I/II enables engraftment and effective function of allogeneic human regulatory T cell therapy in a humanized mouse transplantation model
在人源化小鼠移植模型中，HLA配型或HLA I/II类基因的CRISPR编辑可使同种异体人源调节性T细胞疗法实现植入并发挥有效功能。
期刊:Nature Communications
影响因子:14.7
doi:10.1038/s41467-025-64945-3.
Oliver McCallion #,Weijie Du #,Viktor Glaser #,Kate Milward,Sarah Short,Merve Bilici,Amy Cross,Helen Stark,Clemens Franke,Jonas Kath,Mikhail Valkov,Mingxing Yang,Leila Amini,Annette Künkele,Julia K Polansky,Michael Schmueck-Henneresse,Hans-Dieter Volk,Petra Reinke,Dimitrios L Wagner,Joanna Hester,Fadi Issa
