The presenilin-1 ΔE9 mutation results in reduced γ-secretase activity, but not total loss of PS1 function, in isogenic human stem cells
在同源人类干细胞中，早老素-1 ΔE9 突变导致 γ-分泌酶活性降低，但并未导致 PS1 功能完全丧失
期刊:Cell Reports
影响因子:7.5
doi:10.1016/j.celrep.2013.10.018
Grace Woodruff, Jessica E Young, Fernando J Martinez, Floyd Buen, Athurva Gore, Jennifer Kinaga, Zhe Li, Shauna H Yuan, Kun Zhang, Lawrence S B Goldstein
