日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

The mechanical response of vinculin

黏着斑蛋白的机械反应

Liu, Xuyao; Liu, Jingzhun; Wang, Yinan; Yao, Mingxi; Baker, Karen B; Klapholz, Benjamin; Brown, Nicholas H; Goult, Benjamin T; Yan, Jie

Phagosomal RNA sensing through TLR8 controls susceptibility to tuberculosis

吞噬体RNA通过TLR8进行感知,从而控制对结核病的易感性

Charlotte Maserumule ,Charlotte Passemar ,Olivia S H Oh ,Kriztina Hegyi ,Karen Brown ,Aaron Weimann ,Adam Dinan ,Sonia Davila ,Catherine Klapholz ,Josephine Bryant ,Deepshikha Verma ,Jacob Gadwa ,Shivankari Krishnananthasivam ,Kridakorn Vongtongsalee ,Edward Kendall ,Andres Trelles ,Martin L Hibberd ,Joaquín Sanz ,Jorge Bertol ,Lucia Vázquez-Iniesta ,Kaliappan Andi ,S Siva Kumar ,Diane Ordway ,Rafael Prados-Rosales ,Paul A MacAry ,R Andres Floto

Divergent ontogeny of Tissue Resident Memory and Tissue Resident Exhausted CD8(+) T cells underlies distinct functional potential.

组织驻留记忆 CD8(+) T 细胞和组织驻留耗竭 CD8(+) T 细胞不同的个体发育过程决定了它们不同的功能潜力

Park Simone L, Painter Mark M, Manne Sasikanth, Alcalde Victor, McLaughlin Maura, Sullivan Matthew A, Mathew Divij, Torres Leonel, Huang Yinghui J, Reeg David B, Douek Naomi R, Campos Trenton, Klapholz Max, Cardenas Maria A, Fang Victoria, Ngiow Shin Foong, Kc Wumesh, Goel Rishi R, Baxter Amy E, Wu Jennifer E, Tan Melody, Berry Corbett T, Ellebrecht Christoph T, Huang Alexander C, Papazian Emily, Liu Ying, Rajasekaran Karthik, Brody Robert M, Thaler Erica R, Basu Devraj, Diab Ahmed, Giles Josephine R, Wherry E John

Combined JAK inhibition and PD-1 immunotherapy for non-small cell lung cancer patients

JAK 抑制和 PD-1 免疫治疗联合治疗非小细胞肺癌患者

Divij Mathew #, Melina E Marmarelis #, Caitlin Foley, Joshua M Bauml, Darwin Ye, Reem Ghinnagow, Shin Foong Ngiow, Max Klapholz, Soyeong Jun, Zhaojun Zhang, Robert Zorc, Christiana W Davis, Maximillian Diehn, Josephine R Giles, Alexander C Huang, Wei-Ting Hwang, Nancy R Zhang, Adam J Schoenfeld, Eri

Successful Percutaneous Coronary Stenting in End-Stage Liver Disease Patients Awaiting Liver Transplantation

终末期肝病患者等待肝移植期间经皮冠状动脉支架置入术成功

Raza, Anoshia; Lim, Philip; Shah, Kajol; Sudyn, Alexander; Gerula, Christine; Waller, Alfonso H; Gardin, Julius M; Klapholz, Marc

Migration of Hepatocellular Carcinoma Into the Right Atrium

肝细胞癌向右心房迁移

Siddiqui, Emaad; Solanki, Pallavi; Gerula, Christine; Klapholz, Marc; Waller, Alfonso H

Stat5 opposes the transcription factor Tox and rewires exhausted CD8+ T cells toward durable effector-like states during chronic antigen exposure

Stat5 拮抗转录因子 Tox,并在慢性抗原暴露期间将耗竭的 CD8+ T 细胞重塑为持久的效应样状态。

Jean-Christophe Beltra ,Mohamed S Abdel-Hakeem ,Sasikanth Manne ,Zhen Zhang ,Hua Huang ,Makoto Kurachi ,Leon Su ,Lora Picton ,Shin Foong Ngiow ,Yuki Muroyama ,Valentina Casella ,Yinghui J Huang ,Josephine R Giles ,Divij Mathew ,Jonathan Belman ,Max Klapholz ,Hélène Decaluwe ,Alexander C Huang ,Shelley L Berger ,K Christopher Garcia ,E John Wherry

The interferon-stimulated gene RIPK1 regulates cancer cell intrinsic and extrinsic resistance to immune checkpoint blockade

干扰素刺激基因RIPK1调控癌细胞对免疫检查点阻断的内在和外在抵抗力

Lisa Cucolo ,Qingzhou Chen ,Jingya Qiu ,Yongjun Yu ,Max Klapholz ,Krista A Budinich ,Zhaojun Zhang ,Yue Shao ,Igor E Brodsky ,Martha S Jordan ,D Gary Gilliland ,Nancy R Zhang ,Junwei Shi ,Andy J Minn

Hypoxia induces transgenerational epigenetic inheritance of small RNAs

缺氧诱导小RNA的跨代表观遗传

Simon Yuan Wang, Kathleen Kim, Zach Klapholz O'Brown, Aileen Levan, Anne Elizabeth Dodson, Scott G Kennedy, Chaim Chernoff, Eric Lieberman Greer

Presence of Tim3+ and PD-1+ CD8+ T cells identifies microsatellite stable colorectal carcinomas with immune exhaustion and distinct clinicopathological features

Tim3+ 和 PD-1+ CD8+ T 细胞的存在可识别具有免疫衰竭和独特临床病理特征的微卫星稳定结直肠癌

Max Klapholz #, Michael G Drage #, Amitabh Srivastava, Ana C Anderson