Precision genome editing and in-cell measurements of oxidative DNA damage repair enable functional and mechanistic characterization of cancer-associated MUTYH variants.
精确的基因组编辑和细胞内氧化DNA损伤修复测量能够对癌症相关的MUTYH变体进行功能和机制表征
期刊:Nucleic Acids Research
影响因子:13.1
doi:10.1093/nar/gkaf037
Vasquez Carlos A, Osgood Nicola R B, Zepeda Marcanthony U, Sandel Dominika K, Cowan Quinn T, Peiris Malalage N, Donoghue Daniel J, Komor Alexis C