日期 影响因子
日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:
–

Integrating collecting systems in human kidney organoids through fusion of distal nephron to ureteric bud.

通过将远端肾单位与输尿管芽融合，在人类肾脏类器官中整合集合系统

期刊:Cell Stem Cell
影响因子:20.4
doi:10.1016/j.stem.2025.04.008
Shi Min, Crouse Brittney, Sundaram Nambirajan, Pode Shakked Naomi, Thorner Konrad, King Nathaniel M, Dutta Parna, Ester Lioba, Zhang Weitao, Govindarajah Vinothini, Kopan Raphael, Cebrian Cristina, Mayhew Christopher N, Helmrath Michael A, Bonventre Joseph V, McCracken Kyle W
其它
Human
3D/类器官
发表日期：2025
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Defective Notch1 signaling in endothelial cells drives pathogenesis in a mouse model of Adams-Oliver syndrome

内皮细胞中Notch1信号传导缺陷驱动Adams-Oliver综合征小鼠模型的发病机制

期刊:Journal of Clinical Investigation
影响因子:13.6
doi:10.1172/JCI187532
Solano, Alyssa F; Preusse, Kristina; Cain, Brittany; Hotz, Rebecca; Gavini, Parthav; Yuan, Zhenyu; Bowen, Benjamin; Maco, Gabrielle; Neal, Hope; Gagliani, Ellen K; Ahn, Christopher; Lim, Hee-Woong; Southgate, Laura; Kovall, Rhett A; Kopan, Raphael; Gebelein, Brian
Notch
信号转导
内皮细胞
Notch1
细胞生物学
发表日期：2025
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Bridging the gap of late-gestation nephrogenesis using a non-human primate model

利用非人灵长类动物模型弥合妊娠晚期肾脏发育的差距

期刊:
影响因子:
doi:10.1101/2025.08.18.670897
Thakkar, Kairavee; Yarlagadda, Sunitha; Alkhudairy, Lyan; Potter, Andrew; Thorner, Konrad; Chaturvedi, Praneet; McCracken, Kyle W; Salomonis, Nathan; Kopan, Raphael; Schuh, Meredith P
发育与干细胞
发表日期：2025
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Reduced Nephron Endowment in Six2-TGCtg Mice Is Due to Six3 Misexpression by Aberrant Enhancer-Promoter Interactions in the Transgene.

Six2-TGCtg 小鼠肾单位数量减少是由于转基因中异常的增强子-启动子相互作用导致 Six3 错误表达所致

期刊:Journal of the American Society of Nephrology
影响因子:9.4
doi:10.1681/ASN.0000000000000324
Perl Alison J, Liu Han, Hass Matthew, Adhikari Nirpesh, Chaturvedi Praneet, Hu Yueh-Chiang, Jiang Rulang, Liu Yaping, Kopan Raphael
其它
发表日期：2024
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The unique functions of Runx1 in skeletal muscle maintenance and regeneration are facilitated by an ETS interaction domain

Runx1在骨骼肌维持和再生中的独特功能是由其ETS相互作用域介导的。

期刊:Development
影响因子:3.6
doi:10.1242/dev.202556
Yu, Meng; Thorner, Konrad; Parameswaran, Sreeja; Wei, Wei; Yu, Chuyue; Lin, Xinhua; Kopan, Raphael; Hass, Matthew R
发表日期：2024
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Loss of Notch dimerization perturbs intestinal homeostasis by a mechanism involving HDAC activity

Notch 二聚化的丧失通过涉及 HDAC 活性的机制扰乱肠道稳态

期刊:PLoS Genetics
影响因子:
doi:10.1371/journal.pgen.1011486
Quanhui Dai, Kristina Preusse, Danni Yu, Rhett A Kovall, Konrad Thorner, Xinhua Lin, Raphael Kopan
信号转导
Most
Notch
Donkey
IgG
发表日期：2024
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Integrating collecting systems in kidney organoids through fusion of distal nephron to ureteric bud

通过将远端肾元与输尿管芽融合来整合肾脏类器官中的收集系统

期刊:
影响因子:
doi:10.1101/2024.09.19.613645
Min Shi, Brittney Crouse, Nambirajan Sundaram, Naomi Pode Shakked, Lioba Ester, Weitao Zhang, Vinothini Janakiram, Raphael Kopan, Michael A Helmrath, Joseph V Bonventre, Kyle W McCracken
信号转导
发表日期：2024
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RAAS-deficient organoids indicate delayed angiogenesis as a possible cause for autosomal recessive renal tubular dysgenesis

RAAS 缺陷的类器官表明血管生成延迟可能是常染色体隐性肾小管发育不全的原因

期刊:Nature Communications
影响因子:14.7
doi:10.1038/s41467-023-43795-x
Naomi Pode-Shakked, Megan Slack, Nambirajan Sundaram, Ruth Schreiber, Kyle W McCracken, Benjamin Dekel, Michael Helmrath, Raphael Kopan
信号转导
Donkey
发表日期：2023
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Characterizing post-branching nephrogenesis in the neonatal rabbit

新生兔分支后肾发生的特征

期刊:Scientific Reports
影响因子:3.8
doi:10.1038/s41598-023-46624-9
Meredith P Schuh, Sunitha Yarlagadda, Lyan Alkhudairy, Kristina Preusse, Raphael Kopan
信号转导
FCM
IF
WB
Rabbit
WT1
发表日期：2023
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Reduced nephron endowment in the common Six2-TGC (tg) mouse line is due to Six3 misexpression by aberrant enhancer-promoter interactions in the transgene

常见的 Six2-TGC (tg) 小鼠品系肾单位数量减少是由于转基因中异常的增强子-启动子相互作用导致 Six3 表达异常所致。

期刊:
影响因子:
doi:10.1101/2023.10.06.561202
Perl, Alison J; Liu, Han; Hass, Matthew; Adhikari, Nirpesh; Chaturvedi, Praneet; Hu, Yueh-Chiang; Jiang, Rulang; Liu, Yaping; Kopan, Raphael
发表日期：2023
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