日期 影响因子
日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:
–

Effect of different cross sections of polyetheretherketone splinting bars in maxillary All-on-4(®) implant supported interim prosthesis: finite element analysis study

不同截面聚醚醚酮连接杆对上颌All-on-4®种植体支持式临时修复体的影响：有限元分析研究

期刊:BMC Oral Health
影响因子:3.1
doi:10.1186/s12903-025-06542-w
Abdelrahman, Rana Mohammad; Abdelfattah, Ahmed Mostafa; Kothayer, Marwa
发表日期：2025
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Vitamin D3 mitigates myopathy and metabolic dysfunction in rats with metabolic syndrome: the potential role of dipeptidyl peptidase-4.

维生素 D3 可减轻代谢综合征大鼠的肌病和代谢功能障碍：二肽基肽酶-4 的潜在作用

期刊:Naunyn-Schmiedebergs Archives of Pharmacology
影响因子:3.1
doi:10.1007/s00210-024-03439-3
Shoier Nourhan O, Ghareib Salah A, Kothayer Hend, Alsemeh Amira Ebrahim, El-Sayed Shaimaa S
代谢
发表日期：2025
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Synthesis of new multitarget-directed ligands containing thienopyrimidine nucleus for inhibition of 15-lipoxygenase, cyclooxygenases, and pro-inflammatory cytokines

合成含有噻吩并嘧啶核的新型多靶点导向配体，用于抑制15-脂氧合酶、环氧合酶和促炎细胞因子

期刊:European Journal of Medicinal Chemistry
影响因子:5.9
doi:10.1016/j.ejmech.2023.115443
Abdelkhalek, Ahmed S; Kothayer, Hend; Rezq, Samar; Orabi, Khaled Y; Romero, Damian G; El-Sabbagh, Osama I
细胞生物学
免疫/内分泌
发表日期：2023
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Magic shotgun approach to anti-inflammatory pharmacotherapy: Synthesis of novel thienopyrimidine monomers/heterodimer as dual COX-2 and 15-LOX inhibitors endowed with potent antioxidant activity.

抗炎药物治疗的神奇霰弹枪方法：合成新型噻吩并嘧啶单体/异二聚体作为具有强大抗氧化活性的双重 COX-2 和 15-LOX 抑制剂

期刊:European Journal of Medicinal Chemistry
影响因子:5.9
doi:10.1016/j.ejmech.2023.115724
Elsayed Sara, Abdelkhalek Ahmed S, Rezq Samar, Abu Kull Mansour E, Romero Damian G, Kothayer Hend
炎症/感染
炎症
发表日期：2023
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Triple targeting of mutant EGFR(L858R/T790M), COX-2, and 15-LOX: design and synthesis of novel quinazolinone tethered phenyl urea derivatives for anti-inflammatory and anticancer evaluation.

针对突变型 EGFR(L858R/T790M)、COX-2 和 15-LOX 的三重靶向：新型喹唑啉酮连接的苯基脲衍生物的设计和合成及其抗炎和抗癌评价

期刊:Journal of Enzyme Inhibition and Medicinal Chemistry
影响因子:5.4
doi:10.1080/14756366.2023.2199166
Kothayer Hend, Rezq Samar, Abdelkhalek Ahmed S, Romero Damian G, Elbaramawi Samar S
肿瘤
EGFR
肿瘤免疫
发表日期：2023
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Novel 1,2,4-triazine-quinoline hybrids: The privileged scaffolds as potent multi-target inhibitors of LPS-induced inflammatory response via dual COX-2 and 15-LOX inhibition

新型 1,2,4-三嗪-喹啉杂化物：通过双重 COX-2 和 15-LOX 抑制作为 LPS 诱导炎症反应的强效多靶点抑制剂的优势支架

期刊:European Journal of Medicinal Chemistry
影响因子:6
doi:10.1016/j.ejmech.2021.113457
Amany M Ghanim, Samar Rezq, Tarek S Ibrahim, Damian G Romero, Hend Kothayer
信号转导
发表日期：2021
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Design, computational studies, synthesis and in vitro antimicrobial evaluation of benzimidazole based thio-oxadiazole and thio-thiadiazole analogues

苯并咪唑基硫代恶二唑和硫代噻二唑类似物的设计、计算研究、合成及体外抗菌评价

期刊:BMC Chemistry
影响因子:4.3
doi:10.1186/s13065-021-00785-8
Nada A Noureldin, Jennifer Richards, Hend Kothayer, Mohammed M Baraka, Sobhy M Eladl, Mandy Wootton, Claire Simons
发表日期：2021
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RAD6 promotes DNA repair and stem cell signaling in ovarian cancer and is a promising therapeutic target to prevent and treat acquired chemoresistance

RAD6 促进卵巢癌中的 DNA 修复和干细胞信号传导，是预防和治疗获得性化学耐药的有希望的治疗靶点

期刊:Oncogene
影响因子:6.9
doi:10.1038/onc.2017.279
R R Somasagara, S M Spencer, K Tripathi, D W Clark, C Mani, L Madeira da Silva, J Scalici, H Kothayer, A D Westwell, R P Rocconi, K Palle
信号转导
发育与干细胞
肿瘤
卵巢癌
干细胞
ChIP
发表日期：2017
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Gold nanoparticle conjugated Rad6 inhibitor induces cell death in triple negative breast cancer cells by inducing mitochondrial dysfunction and PARP-1 hyperactivation: Synthesis and characterization

金纳米颗粒偶联的Rad6抑制剂通过诱导线粒体功能障碍和PARP-1过度激活来诱导三阴性乳腺癌细胞死亡：合成与表征

期刊:Nanomedicine-Nanotechnology Biology and Medicine
影响因子:4.6
doi:10.1016/j.nano.2015.10.010
Haynes, Brittany; Zhang, Yanhua; Liu, Fangchao; Li, Jing; Petit, Sarah; Kothayer, Hend; Bao, Xun; Westwell, Andrew D; Mao, Guangzhao; Shekhar, Malathy P V
肿瘤
肿瘤免疫
乳腺癌
线粒体
PARP
细胞生物学
发表日期：2016
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Synthesis and in vitro anticancer evaluation of some 4,6-diamino-1,3,5-triazine-2-carbohydrazides as Rad6 ubiquitin conjugating enzyme inhibitors

合成及体外抗癌活性评价一些4,6-二氨基-1,3,5-三嗪-2-甲酰肼类化合物作为Rad6泛素结合酶抑制剂

期刊:Bioorganic & Medicinal Chemistry Letters
影响因子:2.2
doi:10.1016/j.bmcl.2016.02.085
Kothayer, Hend; Spencer, Sebastian M; Tripathi, Kaushlendra; Westwell, Andrew D; Palle, Komaraiah
肿瘤
肿瘤免疫
发表日期：2016
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