日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Genetic, transcriptomic, histological, and biochemical analysis of progressive supranuclear palsy implicates glial activation and novel risk genes

进行性核上性麻痹的遗传学、转录组学、组织学和生化分析表明神经胶质细胞活化和新的风险基因

Kurt Farrell, Jack Humphrey, Timothy Chang, Yi Zhao, Yuk Yee Leung, Pavel P Kuksa, Vishakha Patil, Wan-Ping Lee, Amanda B Kuzma, Otto Valladares, Laura B Cantwell, Hui Wang, Ashvin Ravi, Claudia De Sanctis, Natalia Han, Thomas D Christie, Robina Afzal, Shrishtee Kandoi, Kristen Whitney, Margaret M K

Spatial proteomics of hippocampal subfield-specific pathology in Alzheimer's disease and primary age-related tauopathy

阿尔茨海默病和原发性年龄相关性 tau 蛋白病的海马亚区特异性病理的空间蛋白质组学

Jamie M Walker, Miranda E Orr, Timothy C Orr, Emma L Thorn, Thomas D Christie, Raquel T Yokoda, Meenakshi Vij, Alexander J Ehrenberg, Gabriel A Marx, Andrew T McKenzie, Justin Kauffman, Enna Selmanovic, Thomas Wisniewski, Eleanor Drummond, Charles L White 3rd, John F Crary, Kurt Farrell, Tiffany F K

Molecular profiling of human substantia nigra identifies diverse neuron types associated with vulnerability in Parkinson's disease

人类黑质的分子分析确定了与帕金森病易感性相关的多种神经元类型

Qian Wang, Minghui Wang, Insup Choi, Lily Sarrafha, Marianna Liang, Lap Ho, Kurt Farrell, Kristin G Beaumont, Robert Sebra, Claudia De Sanctis, John F Crary, Tim Ahfeldt, Joel Blanchard, Drew Neavin, Joseph Powell, David A Davis, Xiaoyan Sun, Bin Zhang, Zhenyu Yue

Single-cell transcriptomic and neuropathologic analysis reveals dysregulation of the integrated stress response in progressive supranuclear palsy

单细胞转录组学和神经病理学分析揭示进行性核上性麻痹中综合应激反应失调

Kristen Whitney, Won-Min Song, Abhijeet Sharma, Diana K Dangoor, Kurt Farrell, Margaret M Krassner, Hadley W Ressler, Thomas D Christie, Shrishtee Kandoi, Ruth H Walker, Melissa J Nirenberg, Steven J Frucht, Giulietta M Riboldi, Bin Zhang, Ana C Pereira, John F Crary4

The relationship between hippocampal amyloid beta burden and spatial distribution of neurofibrillary degeneration

海马淀粉样β蛋白负荷与神经原纤维变性空间分布的关系

Jamie M Walker, William Goette, Kurt Farrell, Megan A Iida, Esma Karlovich; PART Working Group; Charles L White 3rd, John F Crary, Timothy E Richardson

Toward a generalizable machine learning workflow for neurodegenerative disease staging with focus on neurofibrillary tangles

面向神经退行性疾病分期的通用机器学习工作流程,重点关注神经原纤维缠结

Juan C Vizcarra, Thomas M Pearce, Brittany N Dugger, Michael J Keiser, Marla Gearing, John F Crary, Evan J Kiely, Meaghan Morris, Bartholomew White, Jonathan D Glass, Kurt Farrell, David A Gutman

Dysregulated coordination of MAPT exon 2 and exon 10 splicing underlies different tau pathologies in PSP and AD

MAPT 外显子 2 和外显子 10 剪接的失调协调是 PSP 和 AD 中不同 tau 病理的基础

Kathryn R Bowles, Derian A Pugh, Laura-Maria Oja, Benjamin M Jadow, Kurt Farrell, Kristen Whitney, Abhijeet Sharma, Jonathan D Cherry, Towfique Raj, Ana C Pereira, John F Crary, Alison M Goate

Neuroimmune proteins can differentiate between tauopathies

神经免疫蛋白可以区分 tauopathies

Jonathan D Cherry, Zach H Baucom, Kaleb G Eppich, Daniel Kirsch, Erin R Dixon, Yorghos Tripodis, Kevin F Bieniek, Kurt Farrell, Kristen Whitney, Madeline Uretsky, John F Crary, Dennis Dickson, Ann C McKee

Genome-wide association study and functional validation implicates JADE1 in tauopathy

全基因组关联研究和功能验证表明 JADE1 与 tau 蛋白病有关

Kurt Farrell, SoongHo Kim, Natalia Han, Megan A Iida, Elias M Gonzalez, Marcos Otero-Garcia, Jamie M Walker, Timothy E Richardson, Alan E Renton, Shea J Andrews, Brian Fulton-Howard, Jack Humphrey, Ricardo A Vialle, Kathryn R Bowles, Katia de Paiva Lopes, Kristen Whitney, Diana K Dangoor, Hadley Wal

Differential Vulnerability of Hippocampal Subfields in Primary Age-Related Tauopathy and Chronic Traumatic Encephalopathy

原发性年龄相关性 Tau 蛋白病和慢性创伤性脑病中海马亚区的不同脆弱性

Kurt Farrell, Megan A Iida, Jonathan D Cherry, Alicia Casella, Thor D Stein, Kevin F Bieniek, Jamie M Walker, Timothy E Richardson, Charles L White, Victor E Alvarez, Bertrand R Huber, Dennis W Dickson, Ricardo Insausti, Kristen Dams-O'Connor; Part Working Group; Ann C McKee, John F Crary