日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

REST/NRSF Preserves muscle stem cell identity by repressing alternate cell fate.

REST/NRSF 通过抑制其他细胞命运来保持肌肉干细胞的特性

Sahinyan Korin, Blackburn Darren M, Simon Marie-Michelle, Lazure Felicia, Kwan Tony, Wilson David H, Vahidyeganeh Maryam, Alsadi Nawal, von Maltzahn Julia, Yamada Yasuhiro, Jahani-Asl Arezu, Bourque Guillaume, Rudnicki Michael A, Soleimani Vahab D

CpG methylation changes associated with hyperglycemia in type 1 diabetes occur at angiogenic glomerular and retinal gene loci

1型糖尿病高血糖相关的CpG甲基化改变发生在肾小球和视网膜血管生成基因位点。

Shao, Xiaojian; Le Fur, Sophie; Cheung, Warren; Belot, Marie-Pierre; Perge, Kevin; Bouhours-Nouet, Natacha; Bensignor, Candace; Levaillant, Lucie; Ge, Bing; Kwan, Tony; Lathrop, Mark; Pastinen, Tomi; Bougnères, Pierre

Autism-associated CHD8 controls reactive gliosis and neuroinflammation via remodeling chromatin in astrocytes.

与自闭症相关的 CHD8 通过重塑星形胶质细胞中的染色质来控制反应性胶质增生和神经炎症

Megagiannis Platon, Mei Yuan, Yan Rachel E, Yuan Lin, Wilde Jonathan J, Eckersberg Hailey, Suresh Rahul, Tan Xinzhu, Chen Hong, Farmer W Todd, Cha Kuwook, Le Phuong Uyen, Catoire Helene, Rochefort Daniel, Kwan Tony, Yee Brian A, Dion Patrick, Krishnaswamy Arjun, Cloutier Jean-Francois, Stifani Stefano, Petrecca Kevin, Yeo Gene W, Murai Keith K, Feng Guoping, Rouleau Guy A, Ideker Trey, Sanjana Neville E, Zhou Yang

Transposable elements are associated with the variable response to influenza infection

转座因子与对流感感染的不同反应有关

Chen, Xun; Pacis, Alain; Aracena, Katherine A; Gona, Saideep; Kwan, Tony; Groza, Cristian; Lin, Yen Lung; Sindeaux, Renata; Yotova, Vania; Pramatarova, Albena; Simon, Marie-Michelle; Pastinen, Tomi; Barreiro, Luis B; Bourque, Guillaume

Capturing sex-specific and hypofertility-linked effects of assisted reproductive technologies on the cord blood DNA methylome

捕捉辅助生殖技术对脐带血DNA甲基化组的性别特异性和低生育力相关影响

Rahimi, Sophia; Shao, Xiaojian; Chan, Donovan; Martel, Josée; Bérard, Anick; Fraser, William D; Simon, Marie-Michelle; Kwan, Tony; Bourque, Guillaume; Trasler, Jacquetta

Differentially methylated CpGs in response to growth hormone administration in children with idiopathic short stature.

生长激素治疗对特发性矮小症儿童CpG位点差异甲基化的影响

Shao Xiaojian, Le Stunff Catherine, Cheung Warren, Kwan Tony, Lathrop Mark, Pastinen Tomi, Bougnères Pierre

Personalized and graph genomes reveal missing signal in epigenomic data

个性化基因组和图基因组揭示了表观基因组数据中缺失的信号

Groza, Cristian; Kwan, Tony; Soranzo, Nicole; Pastinen, Tomi; Bourque, Guillaume

Dietary Fiber Protects against Diabetic Nephropathy through Short-Chain Fatty Acid-Mediated Activation of G Protein-Coupled Receptors GPR43 and GPR109A

膳食纤维通过短链脂肪酸介导的G蛋白偶联受体GPR43和GPR109A的激活,发挥对糖尿病肾病的保护作用。

Li, Yan Jun; Chen, Xiaochen; Kwan, Tony K; Loh, Yik Wen; Singer, Julian; Liu, Yunzi; Ma, Jin; Tan, Jian; Macia, Laurence; Mackay, Charles R; Chadban, Steven J; Wu, Huiling

Eosinophil microRNAs Play a Regulatory Role in Allergic Diseases Included in the Atopic March

嗜酸性粒细胞微RNA在特应性进程中的过敏性疾病中发挥调控作用

Bélanger, Émile; Madore, Anne-Marie; Boucher-Lafleur, Anne-Marie; Simon, Marie-Michelle; Kwan, Tony; Pastinen, Tomi; Laprise, Catherine

Customized MethylC-Capture Sequencing to Evaluate Variation in the Human Sperm DNA Methylome Representative of Altered Folate Metabolism

定制化甲基C捕获测序用于评估代表叶酸代谢改变的人类精子DNA甲基化组的变异

Chan, Donovan; Shao, Xiaojian; Dumargne, Marie-Charlotte; Aarabi, Mahmoud; Simon, Marie-Michelle; Kwan, Tony; Bailey, Janice L; Robaire, Bernard; Kimmins, Sarah; San Gabriel, Maria C; Zini, Armand; Librach, Clifford; Moskovtsev, Sergey; Grundberg, Elin; Bourque, Guillaume; Pastinen, Tomi; Trasler, Jacquetta M