日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

A highly selective C-H bond fluorination unlocks conformational reporting in a complex natural product derivative

高选择性的CH键氟化反应可揭示复杂天然产物衍生物的构象信息

Ruskin, Jonah; Dekeyser, Roxanne; Garrison, Nathaniel; Williams, Phoebe; Kramer-Johansen, Maya; Majumdar, Ananya; Dudding, Travis; Huczyński, Adam; Lectka, Thomas

A whole-animal phenotypic drug screen identifies suppressors of atherogenic lipoproteins

全动物表型药物筛选可识别致动脉粥样硬化脂蛋白的抑制剂

Daniel J Kelpsch, Liyun Zhang, James H Thierer, Kobe Koren, Urmi Kumar, Yuki Lin, Monica R Hensley, Mira Sohn, Jun O Liu, Thomas Lectka, Jeff S Mumm, Steven A Farber

The Close Interaction of a C-F Bond with an Amide Carbonyl: Crystallographic and Spectroscopic Characterization

CF键与酰胺羰基的紧密相互作用:晶体学和光谱学表征

Harry, Stefan Andrew; Kazim, Muhammad; Nguyen, Phuong Minh; Zhu, Andrea; Xiang, Michael Richard; Catazaro, Jonathan; Siegler, Maxime; Lectka, Thomas

Hydroxy-directed fluorination of remote unactivated C(sp(3))-H bonds: a new age of diastereoselective radical fluorination

羟基导向的远程未活化C(sp(3))-H键氟化:非对映选择性自由基氟化的新时代

Harry, Stefan Andrew; Xiang, Michael Richard; Holt, Eric; Zhu, Andrea; Ghorbani, Fereshte; Patel, Dhaval; Lectka, Thomas

Structural proof of a [C-F-C](+) fluoronium cation

[CFC](+)氟鎓阳离子的结构证明

Hoffmann, Kurt F; Wiesner, Anja; Müller, Carsten; Steinhauer, Simon; Beckers, Helmut; Kazim, Muhammad; Pitts, Cody Ross; Lectka, Thomas; Riedel, Sebastian

Combining asymmetric catalysis with natural product functionalization through enantioselective alpha-fluorination

将不对称催化与天然产物功能化通过对映选择性α-氟化相结合

Erb, Jeremy; Alden-Danforth, Ethan; Kopf, Nathan; Scerba, Michael T; Lectka, Thomas

Catalytic, asymmetric reactions of ketenes and ketene enolates

烯酮和烯酮烯醇盐的催化不对称反应

Paull, Daniel H; Weatherwax, Anthony; Lectka, Thomas

Diastereoselective Synthesis of trans-beta-Lactams Using a Simple Multifunctional Catalyst

利用简单多功能催化剂实现反式-β-内酰胺的非对映选择性合成

Abraham, Ciby J; Paull, Daniel H; Dogo-Isonagie, Cajetan; Lectka, Thomas

Bifunctional asymmetric catalysis: cooperative Lewis acid/base systems

双功能不对称催化:路易斯酸/碱协同体系

Paull, Daniel H; Abraham, Ciby J; Scerba, Michael T; Alden-Danforth, Ethan; Lectka, Thomas

Asymmetric cycloadditions of o-quinone methides employing chiral ammonium fluoride precatalysts

利用手性氟化铵预催化剂的邻醌甲化物不对称环加成反应

Alden-Danforth, Ethan; Scerba, Michael T; Lectka, Thomas