Lee Richard G相关文献与解析，生知库 | 链接生命科学的每一步

Rudler Danielle L, Hughes Laetitia A, King Martin S, Baker Jessica, Lee Richard G, Gandadireja Andrianto P, Sunil Anisha, Fagan Samuel V, Payne Blake, Gray Nicola, McCubbin Tim, Kunji Edmund R S, Rackham Oliver, Filipovska Aleksandra

线粒体

发表日期：2026

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The Lipid Hydrolase ABHD6 is a Therapeutic Target in Metabolic Dysfunction-Associated Steatotic Liver Disease (MASLD)-Related Hepatocellular Carcinoma

脂质水解酶ABHD6是代谢功能障碍相关脂肪肝病（MASLD）相关肝细胞癌的治疗靶点

期刊:

影响因子:

doi:10.1101/2025.07.29.667509

Orabi, Danny; Massey, William J; Fung, Kevin K; Varadharajan, Venkateshwari; Ramachandiran, Iyappan; Banerjee, Rakhee; Silver, Daniel J; Osborn, Lucas J; Brown, Amanda L; Marshall, Stephanie; Ferguson, Daniel; Cao, Shijie; Schugar, Rebecca C; Finney, Chelsea; Neumann, Chase; Burrows, Amy C; Horak, Anthony J; Pathak, Preeti; Helsley, Robert N; Bulfon, Dominik; Zimmermann, Robert; Leung, Yat Hei; Madiraju, S R Murthy; Prentki, Marc; Lee, Richard G; Mullick, Adam E; Zergeeva, Olga; Dasarathy, Srinivasan; Lee, Zhenghong; Allende, Daniela S; Aucejo, Federico; Lathia, Justin D; Brown, J Mark

The nucleotide messenger (p)ppGpp is an anti-inducer of the purine synthesis transcription regulator PurR in Bacillus

核苷酸信使 (p)ppGpp 是芽孢杆菌中嘌呤合成转录调节剂 PurR 的抗诱导剂

期刊:Nucleic Acids Research

影响因子:16.6

doi:10.1093/nar/gkab1281

Brent W Anderson, Maria A Schumacher, Jin Yang, Asan Turdiev, Husan Turdiev, Jeremy W Schroeder, Qixiang He, Vincent T Lee, Richard G Brennan, Jue D Wang

免疫

发表日期：2022

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Stepwise maturation of the peptidyl transferase region of human mitoribosomes.

人类线粒体核糖体肽基转移酶区域的逐步成熟

期刊:Nature Communications

影响因子:15.7

doi:10.1038/s41467-021-23811-8

LenarÄiÄ Tea, Jaskolowski Mateusz, Leibundgut Marc, Scaiola Alain, SchÃ¶nhut Tanja, Saurer Martin, Lee Richard G, Rackham Oliver, Filipovska Aleksandra, Ban Nenad

Hepatocyte-specific suppression of ANGPTL4 improves obesity-associated diabetes and mitigates atherosclerosis in mice

肝细胞特异性抑制ANGPTL4可改善小鼠肥胖相关糖尿病并减轻动脉粥样硬化。

期刊:Journal of Clinical Investigation

影响因子:13.6

doi:10.1172/JCI140989

Singh, Abhishek K; Chaube, Balkrishna; Zhang, Xinbo; Sun, Jonathan; Citrin, Kathryn M; Canfrán-Duque, Alberto; Aryal, Binod; Rotllan, Noemi; Varela, Luis; Lee, Richard G; Horvath, Tamas L; Price, Nathan; Suárez, Yajaira; Fernandez-Hernando, Carlos

Antisense oligonucleotide-mediated inhibition of angiopoietin-like protein 3 increases reverse cholesterol transport in mice.

反义寡核苷酸介导的血管生成素样蛋白 3 抑制作用可增加小鼠体内胆固醇逆向转运

期刊:Journal of Lipid Research

影响因子:4.1

doi:10.1016/j.jlr.2021.100101

Bell Thomas A 3rd, Liu Mingxia, Donner Aaron J, Lee Richard G, Mullick Adam E, Crooke Rosanne M

ApoC-III Glycoforms Are Differentially Cleared by Hepatic TRL (Triglyceride-Rich Lipoprotein) Receptors

ApoC-III 糖型通过肝脏 TRL（富含甘油三酯的脂蛋白）受体进行差异性清除

期刊:Arteriosclerosis Thrombosis and Vascular Biology

影响因子:7.4

doi:10.1161/ATVBAHA.119.312723

Kegulian, Natalie C; Ramms, Bastian; Horton, Steven; Trenchevska, Olgica; Nedelkov, Dobrin; Graham, Mark J; Lee, Richard G; Esko, Jeffrey D; Yassine, Hussein N; Gordts, Philip L S M

信号转导

发表日期：2019

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Hybrid Mouse Diversity Panel Identifies Genetic Architecture Associated with the Acute Antisense Oligonucleotide-Mediated Inflammatory Response to a 2'-O-Methoxyethyl Antisense Oligonucleotide

杂交小鼠多样性分析鉴定出与2'-O-甲氧基乙基反义寡核苷酸介导的急性炎症反应相关的遗传结构

期刊:Nucleic Acid Therapeutics

影响因子:4.7

doi:10.1089/nat.2019.0797

Pirie, Elaine; Cauntay, Patrick; Fu, Wuxia; Ray, Shayoni; Pan, Calvin; Lusis, Aldonis J; Hsiao, Jill; Burel, Sebastien A; Narayanan, Padma; Crooke, Rosanne M; Lee, Richard G

Δ-5 Fatty Acid Desaturase FADS1 Impacts Metabolic Disease by Balancing Proinflammatory and Proresolving Lipid Mediators

Δ-5脂肪酸去饱和酶FADS1通过平衡促炎和促消退脂质介质影响代谢性疾病

期刊:Arteriosclerosis Thrombosis and Vascular Biology

影响因子:7.4

doi:10.1161/ATVBAHA.117.309660

Gromovsky, Anthony D; Schugar, Rebecca C; Brown, Amanda L; Helsley, Robert N; Burrows, Amy C; Ferguson, Daniel; Zhang, Renliang; Sansbury, Brian E; Lee, Richard G; Morton, Richard E; Allende, Daniela S; Parks, John S; Spite, Matthew; Brown, J Mark

代谢

发表日期：2018

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Therapeutic silencing of FSP27 reduces the progression of atherosclerosis in Ldlr(-/-) mice

治疗性沉默FSP27可减缓Ldlr(-/-)小鼠动脉粥样硬化的进展。

期刊:Atherosclerosis

影响因子:5.7

doi:10.1016/j.atherosclerosis.2018.05.045

Rajamoorthi, Ananthi; Lee, Richard G; Baldán, Ángel

Specific SLC25 carriers regulate mitochondrial protein synthesis.

特定的SLC25载体调节线粒体蛋白质合成。

The Lipid Hydrolase ABHD6 is a Therapeutic Target in Metabolic Dysfunction-Associated Steatotic Liver Disease (MASLD)-Related Hepatocellular Carcinoma

脂质水解酶ABHD6是代谢功能障碍相关脂肪肝病（MASLD）相关肝细胞癌的治疗靶点

The nucleotide messenger (p)ppGpp is an anti-inducer of the purine synthesis transcription regulator PurR in Bacillus

核苷酸信使 (p)ppGpp 是芽孢杆菌中嘌呤合成转录调节剂 PurR 的抗诱导剂

Stepwise maturation of the peptidyl transferase region of human mitoribosomes.

人类线粒体核糖体肽基转移酶区域的逐步成熟

Hepatocyte-specific suppression of ANGPTL4 improves obesity-associated diabetes and mitigates atherosclerosis in mice

肝细胞特异性抑制ANGPTL4可改善小鼠肥胖相关糖尿病并减轻动脉粥样硬化。

Antisense oligonucleotide-mediated inhibition of angiopoietin-like protein 3 increases reverse cholesterol transport in mice.

反义寡核苷酸介导的血管生成素样蛋白 3 抑制作用可增加小鼠体内胆固醇逆向转运

ApoC-III Glycoforms Are Differentially Cleared by Hepatic TRL (Triglyceride-Rich Lipoprotein) Receptors

ApoC-III 糖型通过肝脏 TRL（富含甘油三酯的脂蛋白）受体进行差异性清除

Hybrid Mouse Diversity Panel Identifies Genetic Architecture Associated with the Acute Antisense Oligonucleotide-Mediated Inflammatory Response to a 2'-O-Methoxyethyl Antisense Oligonucleotide

杂交小鼠多样性分析鉴定出与2'-O-甲氧基乙基反义寡核苷酸介导的急性炎症反应相关的遗传结构

Δ-5 Fatty Acid Desaturase FADS1 Impacts Metabolic Disease by Balancing Proinflammatory and Proresolving Lipid Mediators

Δ-5脂肪酸去饱和酶FADS1通过平衡促炎和促消退脂质介质影响代谢性疾病

Therapeutic silencing of FSP27 reduces the progression of atherosclerosis in Ldlr(-/-) mice

治疗性沉默FSP27可减缓Ldlr(-/-)小鼠动脉粥样硬化的进展。