日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Targeted CRISPR regulation of ZNF865 enhances stem cell cartilage deposition, tissue maturation rates, and mechanical properties in engineered intervertebral discs

利用 CRISPR 技术靶向调控 ZNF865 可增强干细胞软骨沉积、组织成熟率和工程化椎间盘的力学性能。

Levis, Hunter; Lewis, Christian; Fainor, Matthew; Lawal, Ameerah; Stockham, Elise; Weston, Jacob; Farhang, Niloofar; Gullbrand, Sarah E; Bowles, Robby D

CRISPRa genome-wide screen identifies novel gene targets for osteogenic cell engineering

CRISPRa 全基因组筛选鉴定出成骨细胞工程的新基因靶点

Weston, Jacob D; Levis, Hunter; Lawrence, Brandon; Somoza, Rodrigo; Bowles, Robby D

ZNF865 (BLST) Regulates Human Cell Senescence and DNA Damage.

ZNF865 (BLST) 调控人类细胞衰老和 DNA 损伤

Lewis Christian, Levis Hunter, Holbrook Jonah, Polaski Jacob T, Jacobsen Timothy D, Gullbrand Sarah E, Diekman Brian, Iatridis James C, Gertz Jason, Lawrence Brandon, Bowles Robby D

Therapeutic CRISPR epigenome editing of inflammatory receptors in the intervertebral disc.

利用 CRISPR 技术对椎间盘中的炎症受体进行表观基因组治疗性编辑

Stover Joshua D, Trone Matthew A R, Weston Jacob, Lewis Christian, Levis Hunter, Farhang Niloofar, Philippi Matthew, Zeidan Michelle, Lawrence Brandon, Bowles Robby D

Therapeutic TNF-alpha Delivery After CRISPR Receptor Modulation in the Intervertebral Disc

利用 CRISPR 受体调控技术在椎间盘中递送治疗性 TNF-α

Stover, Joshua D; Trone, Matthew A R; Weston, Jacob; Lewis, Christian; Levis, Hunter; Philippi, Matthew; Zeidan, Michelle; Lawrence, Brandon; Bowles, Robby D